Zobrazeno 1 - 10
of 23
pro vyhledávání: '"Tie‐Jian Jiang"'
Publikováno v:
Frontiers in Cell and Developmental Biology, Vol 8 (2020)
Osteogenesis and senescence of BMSCs play great roles in age-related bone loss. However, the causes of these dysfunctions remain unclear. In this study, we identified a differentially expressed ASPH gene in middle-aged and elderly aged groups which w
Externí odkaz:
https://doaj.org/article/e9774d0736de401395ccd3ccee286711
Autor:
Mi Yang, Chang-Jun Li, Xi Sun, Qi Guo, Ye Xiao, Tian Su, Man-Li Tu, Hui Peng, Qiong Lu, Qing Liu, Hong-Bo He, Tie-Jian Jiang, Min-Xiang Lei, Mei Wan, Xu Cao, Xiang-Hang Luo
Publikováno v:
Nature Communications, Vol 8, Iss 1, Pp 1-11 (2017)
H-type endothelium, defined by the high expression of CD31 and endomucin, is found in the bone where it promotes angiogenesis and osteogensis. Here Yanget al. show that the miR-497∼195 cluster regulates the generation and maintenance of the H-type
Externí odkaz:
https://doaj.org/article/49210989904743bb805bd34eb5fb257a
Autor:
Ya Liu, Yi‐Fan Guo, Hui Peng, Hai‐yan Zhou, Tian Su, Mi Yang, Qi Guo, Xiao Ye, Yan Huang, Tie‐Jian Jiang
Publikováno v:
Cell proliferationREFERENCES.
Hypothalamic dysfunction leads to glucose metabolic imbalance; however, the mechanisms still need clarification. Our current study was to explore the role of hypothalamic Hnscr in glucose metabolism.Using Hnscr knockout or htNSC-specific Hnscr overex
Publikováno v:
Cell Proliferation. 55
DNA N6-methyladenine (N6-mA) demethylase Alkbh1 participates in regulating osteogenic differentiation of mesenchymal stem cell (MSCs) and vascular calcification. However, the role of Alkbh1 in bone metabolism remains unclear.Bone marrow mesenchymal s
Publikováno v:
Molecular Medicine Reports
Osteogenic differentiation of bone marrow mesenchymal stem cells (BMSCs) is regulated by a variety of intracellular regulatory factors including osterix, runt‑related transcription factor 2 (RUNX2), bone morphogenetic proteins and transforming grow
Autor:
Hui Peng, Biao Hu, Ling-Qi Xie, Tian Su, Chang-Jun Li, Ya Liu, Mi Yang, Ye Xiao, Xu Feng, Rui Zhou, Qi Guo, Hai-Yan Zhou, Yan Huang, Tie-Jian Jiang, Xiang-Hang Luo
Publikováno v:
Cell Metabolism. 34:1168-1182.e6
Exercise can prevent osteoporosis and improve immune function, but the mechanism remains unclear. Here, we show that exercise promotes reticulocalbin-2 secretion from the bone marrow macrophages to initiate bone marrow fat lipolysis. Given the crucia
Publikováno v:
Frontiers in Cell and Developmental Biology, Vol 8 (2020)
Osteogenesis and senescence of BMSCs play great roles in age-related bone loss. However, the causes of these dysfunctions remain unclear. In this study, we identified a differentially expressed ASPH gene in middle-aged and elderly aged groups which w
Autor:
Xin-ping Sha, Sha Fu, Jingdong Ma, Chun-hu Zhang, Li-zhi Xiao, Zhao-xin Qian, Yi Ouyang, Tao Tang, Yang Song, Sha-Ling Li, Xiaoyu Fu, Zeng Xiong, Yan Huang, Min Li, Xue-gong Fan, Deming Tan, Jiang-hai Chen, Pinhua Pan, Tie-jian Jiang, Yixiang Zheng, Hui-bao Long
BackgroundThe severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) has progressed to a pandemic associated with substantial morbidity and mortality. The WHO and the United States Center for Disease Control and Prevention (CDC) have issued int
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::36363681f5ad1dd15ac58222e551becd
https://doi.org/10.1101/2020.04.03.20051763
https://doi.org/10.1101/2020.04.03.20051763
Autor:
Mi, Yang, Qi, Guo, Hui, Peng, Yu-Zhong, Xiao, Ye, Xiao, Yan, Huang, Chang-Jun, Li, Tian, Su, Yun-Lin, Zhang, Min-Xiang, Lei, Hui-Ling, Chen, Tie-Jian, Jiang, Xiang-Hang, Luo
Publikováno v:
The Journal of Experimental Medicine
The authors report a mutation in the long noncoding RNA Reg1cp that induces osteogenesis via vascular induction in humans. This mutation affects angiogenesis by blocking Klf3’s repressing activity. The Klf3 antagonist Ophiopogonin D could promote C
Autor:
Hui Peng, Hong-Bo He, Tian Su, Man Li Tu, Tie Jian Jiang, Qi Guo, Mei Wan, Mi Yang, Xiang Hang Luo, Qiong Lu, Qing Liu, Ye Xiao, Changjun Li, Xi Sun, Xu Cao, Min Xiang Lei
Publikováno v:
Nature Communications, Vol 8, Iss 1, Pp 1-11 (2017)
Nature Communications
Nature Communications
A specific bone vessel subtype, strongly positive for CD31 and endomucin (CD31hiEmcnhi), is identified as coupling angiogenesis and osteogenesis. The abundance of type CD31hiEmcnhi vessels decrease during ageing. Here we show that expression of the m