Zobrazeno 1 - 10
of 23
pro vyhledávání: '"Ticilimumab"'
Autor:
Paolo A. Ascierto, Serigne Lo, Carlo Tondini, Richard D. Carvajal, Karijn P M Suijkerbuijk, Kerry L. Reynolds, Jessica S.W. Borgers, Jeremy Lupu, Christian U. Blank, Séverine Roy, Christian Posch, Michael Erdmann, Mario Mandalà, Ines Pires da Silva, Matteo S. Carlino, Maria Grazia Vitale, Tim Cooksley, F. Stephen Hodi, Megan H. Trager, Carola Berking, Leyre Zubiri, Laura Pala, Sharon Nahm, Dirk Schadendorf, Paola Queirolo, Alon Vaisman, Neha Papneja, Paul Lorigan, Joanna Mangana, Aljosja Rogiers, Alexander M. Menzies, Thiago Pimentel Muniz, Caroline Robert, Ryan J. Sullivan, John B. A. G. Haanen, Marcus O. Butler, Reinhard Dummer, Peter Bowling, Wilson H. Miller, Osama E. Rahma, Arielle Elkrief, Samuel D. Saibil, Chiara Tentori, Joseph M. Grimes, Michael Manos, Lisa Zimmer, Georgina V. Long, April A.N. Rose, Axel Hauschild
Publikováno v:
Journal for Immunotherapy of Cancer
Journal for ImmunoTherapy of Cancer
Rogiers, A, Da Silva, I P, Tentori, C, Tondini, C A, Grimes, J M, Trager, M H, Nahm, S, Zubiri, L, Manos, M, Bowling, P, Elkrief, A, Papneja, N, Vitale, M G, Rose, A A N, Borgers, J S W, Roy, S, Mangana, J, Pimentel Muniz, T, Cooksley, T, Lupu, J, Vaisman, A, Saibil, S D, Butler, M O, Menzies, A M, Carlino, M S, Erdmann, M, Berking, C, Zimmer, L, Schadendorf, D, Pala, L, Queirolo, P, Posch, C, Hauschild, A, Dummer, R, Haanen, J, Blank, C U, Robert, C, Sullivan, R J, Ascierto, P A, Miller, W H, Stephen Hodi, F, Suijkerbuijk, K P M, Reynolds, K L, Rahma, O E, Lorigan, P C, Carvajal, R D, Lo, S, Mandala, M & Long, G V 2021, ' Clinical impact of COVID-19 on patients with cancer treated with immune checkpoint inhibition ', Journal for ImmunoTherapy of Cancer, vol. 9, no. 1, e001931 . https://doi.org/10.1136/jitc-2020-001931
Journal for ImmunoTherapy of Cancer, Vol 9, Iss 1 (2021)
Journal for ImmunoTherapy of Cancer
Rogiers, A, Da Silva, I P, Tentori, C, Tondini, C A, Grimes, J M, Trager, M H, Nahm, S, Zubiri, L, Manos, M, Bowling, P, Elkrief, A, Papneja, N, Vitale, M G, Rose, A A N, Borgers, J S W, Roy, S, Mangana, J, Pimentel Muniz, T, Cooksley, T, Lupu, J, Vaisman, A, Saibil, S D, Butler, M O, Menzies, A M, Carlino, M S, Erdmann, M, Berking, C, Zimmer, L, Schadendorf, D, Pala, L, Queirolo, P, Posch, C, Hauschild, A, Dummer, R, Haanen, J, Blank, C U, Robert, C, Sullivan, R J, Ascierto, P A, Miller, W H, Stephen Hodi, F, Suijkerbuijk, K P M, Reynolds, K L, Rahma, O E, Lorigan, P C, Carvajal, R D, Lo, S, Mandala, M & Long, G V 2021, ' Clinical impact of COVID-19 on patients with cancer treated with immune checkpoint inhibition ', Journal for ImmunoTherapy of Cancer, vol. 9, no. 1, e001931 . https://doi.org/10.1136/jitc-2020-001931
Journal for ImmunoTherapy of Cancer, Vol 9, Iss 1 (2021)
BackgroundPatients with cancer who are infected with severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) are more likely to develop severe illness and die compared with those without cancer. The impact of immune checkpoint inhibition (ICI) o
Autor:
Angelica Petrillo, Shelize Khakoo, Nicola Fusco, Massimiliano Salati, Fausto Petrelli, Michele Ghidini, Gianluca Tomasello, Dario Trapani
Publikováno v:
Current drug targets. 22(9)
Immunotherapy has revolutionized the treatment landscape in a number of solid tumors. In colorectal cancer, evidence suggests that microsatellite high (MSI-H) tumors are the most responsive to immune checkpoint blockade due to increased neo-antigen l
Autor:
Edoardo G. Giannini, Andrea Aglitti, Mauro Borzio, Martina Gambato, Maria Guarino, Massimo Iavarone, Quirino Lai, Giovanni Battista Levi Sandri, Fabio Melandro, Filomena Morisco, Francesca Romana Ponziani, Maria Rendina, Francesco Paolo Russo, Rodolfo Sacco, Mauro Viganò, Alessandro Vitale, Franco Trevisani, on behalf of the Associazione Italiana per lo Studio del Fegato (AISF) HCC Special Interest Group
Publikováno v:
Cancers, Vol 11, Iss 11, p 1689 (2019)
Cancers
Cancers
Despite progress in our understanding of the biology of hepatocellular carcinoma (HCC), this tumour remains difficult-to-cure for several reasons, starting from the particular disease environment where it arises—advanced chronic liver disease—to
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5fc7b2e0dd99b8333b4e79f88ccadf75
http://hdl.handle.net/11588/767977
http://hdl.handle.net/11588/767977
Publikováno v:
Seminars in Oncology. 37:460-467
Available medical treatments have limited impact on the survival of patients with advanced cancer; therefore, new therapeutic strategies able to generate more effective host's immune responses against neoplastic cells are being actively pursued. Amon
Autor:
Alexander M.M. Eggermont
Publikováno v:
Annals of Oncology, 21, 339-344. Elsevier Ltd.
After decades of phase III trials failing to demonstrate an impact on survival of various drugs in metastatic melanoma there are finally significant advances in systemic therapies for melanoma emerging. Novel ways to modulate the immune system by mon
Publikováno v:
Hematology-Oncology Clinics of North America, 23(3), 547-+. W.B. Saunders
About 20% of all primary melanomas will spread. The likelihood of metastatic behavior correlates with prognostic factors such as tumor thickness, mitotic index, presence of ulceration, lymphocyte infiltration, age, gender, and anatomic site. Immunoth
Publikováno v:
Pigment Cell & Melanoma Research, 22(2), 156-165. Wiley-Blackwell Publishing Ltd
The following meeting highlights are from the Perspectives in Melanoma XII conference, held in Scheveningen/The Hague, the Netherlands, on October 2-4, 2008. Selected reviews are included but further discussions of these and other presentations are p
Autor:
Changping Li, Viviana Bozon, Luis H. Camacho, Bang Ning Lee, Jesus Gomez-Navarro, Charla A. Parker, James M. Reuben, Ingrid M. Hernandez, Carolina Gutierrez, Gabriel Lopez-Berestein
Publikováno v:
Cancer. 106:2437-2444
BACKGROUND T-regulatory (TR) cells expressing cytotoxic T lymphocyte-associated antigen-4 (CTLA-4) maintain peripheral immune tolerance and negatively affect host immune responses against cancer. The immunobiologic effects of ticilimumab, a human mon
Autor:
Jesus Gomez-Navarro, Elisabeth Seja, Brigitte Englahner, Roberto Renteria, Maribel Ontiveros, Begoña Comin-Anduix, John A. Glaspy, James S. Economou, Deborah L. Reardon, Antoni Ribas, Antonio Gualberto
Publikováno v:
Clinical Cancer Research. 12:107-116
Purpose: Define an immunologic response using the tetramer and enzyme-linked immunospot (ELISPOT) assays. Experimental Design: Ten healthy subjects and 21 patients with melanoma (all HLA-A*0201) donated a total of 121 blood samples to determine the l
Autor:
Yvonne Saenger, John M. Kirkwood, Sara Harcharik, Jay Magidson, Karl Wassmann, Yichun Fu, Bobby Chi-Hung Liaw, Ellen H de Moll, Philip Friedlander, David E. Fisher, William Oh
Publikováno v:
Clinical cancer research : an official journal of the American Association for Cancer Research. 20(12)
Purpose: Tremelimumab (ticilimumab, Pfizer), is a monoclonal antibody (mAb) targeting cytotoxic T lymphocyte–associated antigen-4 (CTLA-4). Ipilimumab (Yervoy, BMS), another anti-CTLA-4 antibody, is approved by the U.S. Federal Drug Administration