Zobrazeno 1 - 10
of 11
pro vyhledávání: '"Tibor I. Matula"'
Publikováno v:
Drug Information Journal. 28:159-162
This paper describes the current state of toxicokinetics in Canada from a regulator’s viewpoint. The Canadian Health Protection Branch supports the use of toxicokinetics and believes that an integrated approach which combines toxicokinetic evaluati
Autor:
Kenneth L. Hastings, James L. Weaver, Naohisa Tsutsui, Peter Ulrich, Hirofumi Kusunoki, Jan Willem van der Laan, Henk Van Loveren, S. Spanhaak, Jean-Marc Vidal, Jennifer Sims, Stephen K. Durham, Tibor I. Matula, Jun-ichi Sawada, Thomas T. Kawabata, Kazuichi Nakamura, Osamu Fueki, Shigeru Hisada
Publikováno v:
Journal of Immunotoxicology, 2, 171-180. Informa Healthcare
An anonymous survey of pharmaceutical industry practices for immunotoxicology evaluation was conducted. This was in support of the development of the guideline on the preclinical evaluation of unintended modulation of the immune system for the Intern
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::befea13b40dab8c6e3455a49f275cedd
https://cris.maastrichtuniversity.nl/en/publications/8b0cf2f9-c658-4c82-a3ff-896df9ca72c9
https://cris.maastrichtuniversity.nl/en/publications/8b0cf2f9-c658-4c82-a3ff-896df9ca72c9
Publikováno v:
Molecular biotechnology. 6(3)
The isolation of intact RNA from rat pancreas is compromised by autolysis and by the presence of endogenous ribonucleases. In order to ameliorate recovery we systematically investigated available RNA extraction methods and paid particular attention t
Publikováno v:
Mutation Research/Genetic Toxicology. 79:203-212
About 300 compounds have been reported in the literature as constituents of pulp-mill effluent. Previously, in our screening program, 10 resin acids identified in effluent were examined for potential mutagenicity in the Salmonella/mammalian-microsome
Publikováno v:
Canadian Journal of Genetics and Cytology. 22:35-40
A chemical reaction occurs when trichloroacetic acid (TCA) is dissolved in dimethyl sulphoxide (DMSO), with the production of a short-lived mutagenic derivative which was detected using the Salmonella/mammalian-microsome plate overlay assay. Other in
Publikováno v:
Journal of Bacteriology. 94:1764-1777
When cells of a marine pseudomonad were washed and suspended in 0.5 m sucrose, they retained their rod shape, but thin sections, when examined in an electron microscope, revealed that the outer layer of the cell wall had separated a considerable dist
Autor:
Robert A. MacLeod, Tibor I. Matula
Publikováno v:
Canadian Journal of Microbiology. 8:883-896
Five marine bacteria examined were found to differ considerably in lytic susceptibility. Some lysed completely below 0.15 M NaCl while suspensions of others contained some whole cells at 0.025 M NaCl. In general NaCl and LiCl were more effective than
Autor:
Tibor I. Matula, Robert A. MacLeod
Publikováno v:
Journal of Bacteriology. 100:403-410
When cells of a marine pseudomonad washed free of medium components with 0.05 m MgSO 4 were suspended in solutions containing 200-m m concentrations of various salts, there was an immediate increase in optical density (OD), followed by a slow decreas
Autor:
Tibor I. Matula, Robert A. MacLeod
Publikováno v:
Journal of Bacteriology. 100:411-416
When cells of Pseudomonas aeruginosa were suspended in solutions containing increasing concentrations of NaCl, the optical density (OD) of the suspensions measured within 30 sec was found to increase in proportion to the increase in salt concentratio
Publikováno v:
Journal of Bacteriology. 92:63-71
Drapeau, Gabriel R., (McGill University, Montreal, Quebec, Canada), Tibor I. Matula, and Robert A. MacLeod . Nutrition and metabolism of marine bacteria. XV. Relation of Na + -activated transport to the Na + requirement of a marine pseudomonad for gr