Zobrazeno 1 - 10
of 42
pro vyhledávání: '"Tibor, Vántus"'
Autor:
Attila Varga, Minh Tu Nguyen, Kinga Pénzes, Bence Bátai, Pál Gyulavári, Bianka Gurbi, József Murányi, Péter Csermely, Miklós Csala, Tibor Vántus, Csaba Sőti
Publikováno v:
Cells, Vol 12, Iss 2, p 212 (2023)
Prostate cancer metastasis is a significant cause of mortality in men. PKD3 facilitates tumor growth and metastasis, however, its regulation is largely unclear. The Hsp90 chaperone stabilizes an array of signaling client proteins, thus is an enabler
Externí odkaz:
https://doaj.org/article/a25c4d7aca6d4c5f82f3e3ec898a3af3
Autor:
Attila Varga, Pál Gyulavári, Zoltán Greff, Krisztina Futosi, Tamás Németh, Laura Simon-Szabó, Krisztina Kerekes, Csaba Szántai-Kis, Diána Brauswetter, Márton Kokas, Gábor Borbély, Anna Erdei, Attila Mócsai, György Kéri, Tibor Vántus
Publikováno v:
PLoS ONE, Vol 10, Iss 12, p e0144792 (2015)
Externí odkaz:
https://doaj.org/article/55ac64e255ec4adb9ce3d6c16ecbc5c2
Autor:
Attila Varga, Pál Gyulavári, Zoltán Greff, Krisztina Futosi, Tamás Németh, Laura Simon-Szabó, Krisztina Kerekes, Csaba Szántai-Kis, Diána Brauswetter, Márton Kokas, Gábor Borbély, Anna Erdei, Attila Mócsai, György Kéri, Tibor Vántus
Publikováno v:
PLoS ONE, Vol 10, Iss 4, p e0124234 (2015)
Emerging evidence suggests that the vascular endothelial growth factor receptor 2 (VEGFR2) and protein kinase D1 (PKD1) signaling axis plays a critical role in normal and pathological angiogenesis and inflammation related processes. Despite all effor
Externí odkaz:
https://doaj.org/article/e59f67d585014cf3805d900a5d2cab4d
Autor:
Györgyi Bökönyi, Attila Varga, Krisztina Ludányi, György Kéri, Tibor Vántus, Pál Gyulavári, Domonkos Pap, József Murányi, Henriette Tanai, Gábor Mező
Publikováno v:
Journal of Peptide Science. 22:552-560
Targeted tumour therapy is the focus of recent cancer research. Gonadotropin-releasing hormone (GnRH) analogues are able to deliver anticancer agents selectively into tumour cells, which highly express GnRH receptors. However, the effectiveness of di
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::02c3cc3cd3279c98b8c542d8612a7cb3
https://doi.org/10.1002/psc.2904
https://doi.org/10.1002/psc.2904
Autor:
Péter Bánhegyi, Zoltán Greff, Axel Ullrich, Tibor Vántus, László Őrfi, József Mandl, György Kéri, Laura Simon-Szabó, Csaba Szántai-Kis, Sándor Boros, Márton Kokas, Lilian Zsákai, Miklós Csala, Gábor Bánhegyi, István Vályi-Nagy
Publikováno v:
Bioorganic & Medicinal Chemistry Letters. 26:424-428
Activation of various interacting stress kinases, particularly the c-Jun N-terminal kinases (JNK), and a concomitant phosphorylation of insulin receptor substrate 1 (IRS-1) at serine 307 play a central role both in insulin resistance and in β-cell d
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9e6a1a75d264d9775c6078b36286ed7b
https://doi.org/10.1016/j.bmcl.2015.11.099
https://doi.org/10.1016/j.bmcl.2015.11.099
Publikováno v:
Journal of Visualized Experiments.
GnRH analogues are effective targeting moieties and able to deliver anticancer agents selectively into malignant tumor cells which highly express GnRH receptors. However, the quantitative analysis of GnRH analogues' cellular uptake and the investigat
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8b9ae4513ea8d20344f6c22dff9e4437
https://doi.org/10.3791/55529
https://doi.org/10.3791/55529
Autor:
Laszlo Orfi, Axel Ullrich, Bálint Szokol, Ferenc Baska, Pál Gyulavári, Tibor Vántus, Zoltán Greff, Robert Torka, Csaba Szántai-Kis, Zoltan Örfi, István Peták, Ibolya Kurko, Kinga Pénzes, György Kéri
Publikováno v:
ACS Medicinal Chemistry Letters. 5:298-303
Activating mutations in the epidermal growth factor receptor (EGFR) have been identified in a subset of non-small cell lung cancer (NSCLC), which is one of the leading cancer types worldwide. Application of EGFR tyrosine kinase inhibitors leads to ac
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7dfdf065c9480b7975be5941c38a6996
https://doi.org/10.1021/ml4003309
https://doi.org/10.1021/ml4003309
Publikováno v:
Annals of Oncology. 30:v806
Background Prostate cancer is the second leading cause of cancer related deaths in men worldwide. Heat Shock Protein 90 (Hsp90) is expressed in tumour cells at high levels – 3-5% of total proteins – and regulates the function of oncogenes and oth
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::8b9a26bbb774a49dbd33890d102480d5
https://doi.org/10.1093/annonc/mdz269.030
https://doi.org/10.1093/annonc/mdz269.030
Autor:
József, Murányi, Pál, Gyulavári, Attila, Varga, Györgyi, Bökönyi, Henriette, Tanai, Tibor, Vántus, Domonkos, Pap, Krisztina, Ludányi, Gábor, Mező, György, Kéri
Publikováno v:
Journal of peptide science : an official publication of the European Peptide Society. 22(8)
Targeted tumour therapy is the focus of recent cancer research. Gonadotropin-releasing hormone (GnRH) analogues are able to deliver anticancer agents selectively into tumour cells, which highly express GnRH receptors. However, the effectiveness of di
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::39db1591348b6d8f7dd694b9d66cb9ed
https://pubmed.ncbi.nlm.nih.gov/27443981
https://pubmed.ncbi.nlm.nih.gov/27443981
Autor:
Tibor Vántus, T. Lorand, Attila Varga, M. Idei, Attila Agócs, Anikó Horváth, József Mandl, Gy. Kéri, Monika Huszar
Publikováno v:
Current Medicinal Chemistry. 17:321-333
Compound lipophilicity connected to ADME(T)(a) has great importance in drug development and it has to be evaluated by the generally used drug developmental process. In addition to the importance of lipophilicity in ADMET, recently it has been reporte
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3ae6e1c4bc599b4cd0f8f47ef7bbeefe
https://doi.org/10.2174/092986710790192703
https://doi.org/10.2174/092986710790192703