Zobrazeno 1 - 7
of 7
pro vyhledávání: '"Tiarne van de Walle"'
Publikováno v:
Frontiers in Immunology, Vol 14 (2023)
Tertiary lymphoid structures (TLS) are lymph node-like aggregates that can form in association with chronic inflammation or cancer. Mature TLS are organized into B and T cell zones, and are not encapsulated but include all cell types necessary for el
Externí odkaz:
https://doaj.org/article/bd5ff71ca3964590bb3ec6357e6c95ad
Autor:
Luuk van Hooren, Alessandra Vaccaro, Mohanraj Ramachandran, Konstantinos Vazaios, Sylwia Libard, Tiarne van de Walle, Maria Georganaki, Hua Huang, Ilkka Pietilä, Joey Lau, Maria H. Ulvmar, Mikael C. I. Karlsson, Maria Zetterling, Sara M. Mangsbo, Asgeir S. Jakola, Thomas Olsson Bontell, Anja Smits, Magnus Essand, Anna Dimberg
Publikováno v:
Nature Communications, Vol 12, Iss 1, Pp 1-14 (2021)
Agonistic CD40 antibodies (αCD40) have broad immunostimulatory properties, however their efficacy in glioma remains unclear. Here the authors show that αCD40 promotes the formation of tertiary lymphoid structures but does not improve survival and i
Externí odkaz:
https://doaj.org/article/960c23767579410eb75556847b8c9b3f
Autor:
Tiarne van de Walle, Alessandra Vaccaro, Mohanraj Ramachandran, Ilkka Pietilä, Magnus Essand, Anna Dimberg
Publikováno v:
Frontiers in Immunology, Vol 12 (2021)
Glioblastoma is the most common and aggressive brain tumor, which is uniformly lethal due to its extreme invasiveness and the absence of curative therapies. Immune checkpoint inhibitors have not yet proven efficacious for glioblastoma patients, due i
Externí odkaz:
https://doaj.org/article/a4c01f1f7ad04ec987069b0c873b458a
Autor:
Mohanraj Ramachandran, Alessandra Vaccaro, Tiarne van de Walle, Maria Georganaki, Roberta Lugano, Kalyani Vemuri, Despoina Kourougkiaouri, Konstantinos Vazaios, Marie Hedlund, Georgia Tsaridou, Lene Uhrbom, Ilkka Pietilä, Miika Martikainen, Luuk van Hooren, Thomas Olsson Bontell, Asgeir S. Jakola, Di Yu, Bengt Westermark, Magnus Essand, Anna Dimberg
Publikováno v:
Cancer Cell.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::8fac666d92e89c1d9cb950afcd918920
https://doi.org/10.1016/j.ccell.2023.04.010
https://doi.org/10.1016/j.ccell.2023.04.010
Autor:
Anna Dimberg, Bàrbara Laviña, Maria Georganaki, Lei Liu Conze, Hua Huang, Luuk van Hooren, Kalyani Vemuri, Tiarne van de Walle, Liqun He, Lei Zhang, Roberta Lugano, Mohanraj Ramachandran, Peetra U. Magnusson, Fredrik Pontén, Christer Betsholtz, Michael Bergqvist, Elisabetta Dejana, Anja Smits
Publikováno v:
Neuro Oncol
Background Tumor vessels in glioma are molecularly and functionally abnormal, contributing to treatment resistance. Proteins differentially expressed in glioma vessels can change vessel phenotype and be targeted for therapy. ELTD1 (Adgrl4) is an orph
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::810ec56d98bdf9c70cf044019567adcd
https://pubmed.ncbi.nlm.nih.gov/35015881
https://pubmed.ncbi.nlm.nih.gov/35015881
Autor:
Anna Dimberg, Konstantinos Vazaios, Thomas Olsson Bontell, Hua Huang, Mikael C. I. Karlsson, Alessandra Vaccaro, Maria Georganaki, Tiarne van de Walle, Maria Zetterling, Asgeir Store Jakola, Magnus Essand, Sylwia Libard, Anja Smits, Sara M. Mangsbo, Mohanraj Ramachandran, Joey Lau, Luuk van Hooren, Maria H. Ulvmar, Ilkka Pietilä
Publikováno v:
Nature Communications
Nature Communications, Vol 12, Iss 1, Pp 1-14 (2021)
Nature Communications, Vol 12, Iss 1, Pp 1-14 (2021)
Gliomas are brain tumors characterized by an immunosuppressive microenvironment. Immunostimulatory agonistic CD40 antibodies (αCD40) are in clinical development for solid tumors, but are yet to be evaluated for glioma. Here, we demonstrate that syst
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a2c7bcaca1373ab46811cd5db7910491
http://europepmc.org/articles/PMC8257767
http://europepmc.org/articles/PMC8257767
Autor:
Anna Dimberg, Joey Lau, Maria H. Ulvmar, Asgeir Store Jakola, Anja Smits, Sylwia Libard, Hua Huang, Maria Zetterling, Konstantinos Vazaios, Luuk van Hooren, Mikael C. I. Karlsson, Maria Georganaki, Thomas Olsson Bontell, Alessandra Vaccaro, Magnus Essand, Tiarne van de Walle, Ilkka Pietilä, Sara M. Mangsbo, Mohanraj Ramachandran
Gliomas are brain tumors characterized by immunosuppression. Immunostimulatory agonistic CD40 antibodies (αCD40) are in clinical development for solid tumors but are yet to be evaluated for glioma. Here, systemic delivery of αCD40 led to cytotoxic
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::4ad36635cfc018cb12848f32123cc163
https://doi.org/10.1101/2021.01.05.425377
https://doi.org/10.1101/2021.01.05.425377
