Tight Junction Protein Claudin-7 Is Essential for Intestinal Epithelial Stem Cell Self-Renewal and DifferentiationSummary

Autor: Tiaosi Xing, Lesley Jasmine Benderman, Stephiya Sabu, Joel Parker, Jeffrey Yang, Qun Lu, Lei Ding, Yan-Hua Chen

Publikováno v: Cellular and Molecular Gastroenterology and Hepatology, Vol 9, Iss 4, Pp 641-659 (2020)

Background & Aims: Claudin-7 (Cldn7) is a tight junction (TJ) membrane protein located at the apical TJ and basolateral side of intestinal epithelial cells. Deletion of Cldn7 by gene targeting leads to the inflammatory bowel disease–like phenotype

Externí odkaz: https://doaj.org/article/e4aea25258894877a5f2e51c5bc54774

The substantia nigra modulates proximal colon tone and motility in a vagally-dependent manner in the rat

Autor: Tiaosi Xing, Giorgia Nanni, Cameron Burkholde, Kirsteen Browning, R. Alberto Travagli

Publikováno v: Physiology. 38

Previous studies have shown that a monosynaptic pathway connects the substantia nigra pars compacta (SNpc) to neurons of the dorsal motor nucleus of the vagus (DMV). This monosynaptic pathway modulates the vagal control of gastric motility. The prese

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::36d93c589b8435f7aa50f1a6a8479a45
https://doi.org/10.1152/physiol.2023.38.s1.5733721

The nigro-vagal modulation of the proximal colon is compromised in a model of environmental Parkinson's Disease

Autor: Tiaosi Xing, Giorgia Nanni, Cameron Burkholde, Kirsteen Browning, R. Alberto Travagli

Publikováno v: Physiology. 38

Parkinson’s Disease (PD) is a prevalent neurodegenerative disease characterized by progressive loss of dopaminergic neurons in the substantia nigra pars compacta (SNpc), which results in tremor, rigidity and bradykinesia. Up to 80% of the PD patien

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::155b0d5f719439e992623f1d84e0a637
https://doi.org/10.1152/physiol.2023.38.s1.5733401

Association between gene polymorphism of GRK5 and breast cancer risk in Chinese population

Autor: Binbin, Wu, Tiaosi, Xing, Huixin, Li, Waner, He, Bojian, Li

Publikováno v: Journal of B.U.ON. : official journal of the Balkan Union of Oncology. 26(3)

Potential influences of GRK5 polymorphism on cancer risks have been reported. This study aimed to explore the distribution of GRK5 genotypes and alleles in Chinese breast cancer (BCa) patients, and to analyze the association between GRK5 and BCa risk

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmid________::e1da044d3d1af50fc77bf705fe114cb5
https://pubmed.ncbi.nlm.nih.gov/34268929

Tight Junction Protein Claudin-7 Is Essential for Intestinal Epithelial Stem Cell Self-Renewal and Differentiation

Autor: Qun Lu, Lei Ding, Yan-Hua Chen, Lesley Jasmine Benderman, Joel S. Parker, Tiaosi Xing, Stephiya Sabu, Jeffrey Yang

Publikováno v: Cellular and Molecular Gastroenterology and Hepatology, Vol 9, Iss 4, Pp 641-659 (2020)
Cellular and Molecular Gastroenterology and Hepatology

Background & Aims Claudin-7 (Cldn7) is a tight junction (TJ) membrane protein located at the apical TJ and basolateral side of intestinal epithelial cells. Deletion of Cldn7 by gene targeting leads to the inflammatory bowel disease–like phenotype i

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b09406cc28198905364c0398869c795e