Zobrazeno 1 - 10
of 15
pro vyhledávání: '"Tianzhen Han"'
Publikováno v:
Mathematics, Vol 11, Iss 14, p 3162 (2023)
Federated learning has become increasingly important for modern machine learning, especially for data privacy sensitive scenarios. Existing federated learning mainly adopts a central server-based network topology, however, the training process of whi
Externí odkaz:
https://doaj.org/article/61464af40b5d437a893bb041e3f79221
Autor:
Mukundan Attur, Xin Duan, Lei Cai, Tianzhen Han, Weili Zhang, Eric D. Tycksen, Jonathan Samuels, Robert H. Brophy, Steven B. Abramson, Muhammad Farooq Rai
Publikováno v:
Arthritis Research & Therapy, Vol 23, Iss 1, Pp 1-14 (2021)
Abstract Background Elevated levels of periostin (Postn) in the cartilage and bone are associated with osteoarthritis (OA). However, it remains unknown whether Postn loss-of-function can delay or prevent the development of OA. In this study, we sough
Externí odkaz:
https://doaj.org/article/539326da7b6e4804afcdfd7eb108f332
Membrane-type 1 Matrix Metalloproteinase Modulates Tissue Homeostasis by a Non-proteolytic Mechanism
Autor:
Mukundan Attur, Cuijie Lu, Xiaodong Zhang, Tianzhen Han, Cassidy Alexandre, Cristina Valacca, Shuai Zheng, Sarina Meikle, Branka Brukner Dabovic, Evelyne Tassone, Qing Yang, Victoria Kolupaeva, Shoshana Yakar, Steven Abramson, Paolo Mignatti
Publikováno v:
iScience, Vol 23, Iss 12, Pp 101789- (2020)
Summary: Membrane-type 1 matrix metalloproteinase (MT1-MMP, MMP-14), a transmembrane proteinase with a short cytoplasmic tail, is a major effector of extracellular matrix remodeling. Genetic silencing of MT1-MMP in mouse (Mmp14−/−) and man causes
Externí odkaz:
https://doaj.org/article/c75bb8befb1a45eeb5542b86036af6fd
Publikováno v:
PLoS ONE, Vol 15, Iss 4, p e0231501 (2020)
Osteoarthritis (OA) is characterized by progressive loss of articular cartilage accompanied by the new bone formation and, often, a synovial proliferation that culminates in pain, loss of joint function, and disability. However, the cellular and mole
Externí odkaz:
https://doaj.org/article/d80471055d814a9689afcd5235349ec1
Autor:
Tianwu Yang, Junfei Zhou, Xue Liang, Tianzhen Han, Chen Zhao, Yu Liu, Jiaxin Li, Xuemei Ji, Nannan Kang
Publikováno v:
Cell Death and Disease, Vol 11, Iss 11, Pp 1-13 (2020)
Cell Death & Disease
Cell Death & Disease
Bevacizumab in neoadjuvant therapy provides a new hope of improved survival for patients with triple-negative breast cancer (TNBC) by targeting vascular endothelial growth factor in combination with chemotherapy, but curative effect is limited by bev
Autor:
Weili Zhang, Muhammad Farooq Rai, Xin Duan, Tianzhen Han, Mukundan Attur, Lei Cai, Robert H. Brophy, Steven B. Abramson, Eric Tycksen, Jonathan Samuels
Publikováno v:
Arthritis Research & Therapy
Arthritis Research & Therapy, Vol 23, Iss 1, Pp 1-14 (2021)
Arthritis Research & Therapy, Vol 23, Iss 1, Pp 1-14 (2021)
Background Elevated levels of periostin (Postn) in the cartilage and bone are associated with osteoarthritis (OA). However, it remains unknown whether Postn loss-of-function can delay or prevent the development of OA. In this study, we sought to bett
Membrane-type 1 Matrix Metalloproteinase Modulates Tissue Homeostasis by a Non-proteolytic Mechanism
Autor:
Cuijie Lu, Steven B. Abramson, Evelyne Tassone, Sarina Meikle, Paolo Mignatti, Cassidy Alexandre, Qing X. Yang, Tianzhen Han, Victoria Kolupaeva, Cristina Valacca, Branka Dabovic, Shoshana Yakar, Shuai Zheng, Xiaodong Zhang, Mukundan Attur
Publikováno v:
iScience
iScience, Vol 23, Iss 12, Pp 101789-(2020)
iScience, Vol 23, Iss 12, Pp 101789-(2020)
Summary Membrane-type 1 matrix metalloproteinase (MT1-MMP, MMP-14), a transmembrane proteinase with a short cytoplasmic tail, is a major effector of extracellular matrix remodeling. Genetic silencing of MT1-MMP in mouse (Mmp14−/−) and man causes
Publikováno v:
PLoS ONE, Vol 15, Iss 4, p e0231501 (2020)
PLoS ONE
PLoS ONE
Osteoarthritis (OA) is characterized by progressive loss of articular cartilage accompanied by the new bone formation and, often, a synovial proliferation that culminates in pain, loss of joint function, and disability. However, the cellular and mole
Autor:
Xiaodong Zhang, Tianzhen Han, Victoria Kolupaeva, Evelyne Tassone, Qing X. Yang, Cuijie Lu, Cristina Valacca, Branka Dabovic, Mukundan Attur, Paolo Mignatti, Cassidy Alexandre, Shuai Zheng, Sarina Meikle, Shoshana Yakar, Steven B. Abramson
Publikováno v:
SSRN Electronic Journal.
SUMMARYMembrane-type 1 matrix metalloproteinase (MT1-MMP, MMP-14), a transmembrane proteinase with a short cytoplasmic tail, is a major effector of extracellular matrix (ECM) remodeling. Genetic silencing of MT1-MMP in mouse (Mmp14−/−) and man ca
Autor:
Lei Cai, S.B. Abramson, Weili Zhang, Mukundan Attur, Muhammad Farooq Rai, Tianzhen Han, Jonathan Samuels, Xin Duan, R.H. Brophy
Publikováno v:
Osteoarthritis and Cartilage. 29:S99-S100