Výsledky vyhledávání - "Tianyang Ren"

Goserelin/PLGA solid dispersion used to prepare long-acting microspheres with reduced initial release and reduced fluctuation of drug serum concentration in vivo

Autor: Tianyang Ren, Jin Chen, Pan Qi, Peifu Xiao, Puxiu Wang

Publikováno v: International journal of pharmaceutics. 615

To prepare Goserelin (GOS) loaded long-acting microspheres with reduced initial release and prolonged drug release time of GOS, GOS/PLGA solid dispersion (by hot-melt extrusion, HME) was dissolved/dispersed in dichloromethane (DCM) to prepare microsp

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::907e9fcc8e52aab7d3ca13d8c6490d90
https://pubmed.ncbi.nlm.nih.gov/35041918

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Bioadhesive poly(methyl vinyl ether-co-maleic anhydride)-TPGS copolymer modified PLGA/lipid hybrid nanoparticles for improving intestinal absorption of cabazitaxel

Autor: Ruixue Bai, Xuehua Zheng, Tianyang Ren, Lingyan Jian, Yuehui Yang

Publikováno v: International Journal of Pharmaceutics. 611:121301

A bioadhesive nanocarrier, PTNP, was constructed by utilizing a novel poly(methyl vinyl ether-co-maleic anhydride)- D-α-Tocopheryl polyethylene glycol succinate (PVMMA-TPGS) copolymer in the PLGA/lipid hybrid nanoparticles (PLGA NPs) for improving o

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c84e796c7ae347cb0f2db890c0cf861c
https://doi.org/10.1016/j.ijpharm.2021.121301

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Strategies for improving the payload of small molecular drugs in polymeric micelles

Autor: Xiaolin Liu, Bin Tian, Xiaoguang Tao, Pengqian Tian, Ling Zhang, Dandan Yu, Xing Tang, Tianyang Ren, Jianbo Song, Yanhui Chao, Jingxin Gou, Yu Zhang, Wei Xiao

Publikováno v: Journal of Controlled Release. 261:352-366

In the past few years, substantial efforts have been made in the design and preparation of polymeric micelles as novel drug delivery vehicles. Typically, polymeric micelles possess a spherical core-shell structure, with a hydrophobic core and a hydro

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8b2c19b3fede051064afc52e416900ff
https://doi.org/10.1016/j.jconrel.2017.01.047

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Modified PLGA–PEG–PLGA thermosensitive hydrogels with suitable thermosensitivity and properties for use in a drug delivery system

Autor: Jingxin Gou, Haibing He, Xing Tang, Xuezhi Zhuo, Tianyang Ren, Wei Chu, Puxiu Wang, Tian Yin, Yu Zhang

Publikováno v: Journal of Materials Chemistry B. 5:1551-1565

PLGA-PEG-PLGA (PPP) triblock copolymer is the most widely studied thermosensitive hydrogel owing to its non-toxic, biocompatible, biodegradable, and thermosensitive properties. PPP thermosensitive hydrogels are being investigated as in situ gels beca

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::732854b093e43c7c2dbc717851b052a9
https://doi.org/10.1039/c6tb02158a

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