Zobrazeno 1 - 10
of 28
pro vyhledávání: '"Tianyan Chi"'
Autor:
Wenjing Song, Yang Yao, Heling Zhang, Xin Hao, Liping Zhou, Zhixiao Song, Tiantian Wei, Tianyan Chi, Peng Liu, Xuefei Ji, Libo Zou
Publikováno v:
Molecules, Vol 28, Iss 1, p 390 (2023)
Diabetes mellitus (DM) is a major risk factor for stroke and exacerbates white-matter damage in focal cerebral ischemia. Our previous study showed that the sigma-1 receptor agonist PRE084 ameliorates bilateral common-carotid-artery occlusion-induced
Externí odkaz:
https://doaj.org/article/5e99738512874bba973f19dd4d6a605b
Autor:
Peng Liu, Guoliang Chen, Xuefei Ji, Tianyan Chi, Zheng Zhonghui, Libo Zou, Xuefei Bao, Xiaoli Guo, Xiaojuan Wang, Danyang Liu
Publikováno v:
ACS Chemical Neuroscience. 12:3985-3993
In Alzheimer's disease (AD), damaged Aβ clearance contributes to elevated levels of Aβ that cause a series of cytotoxic cascade reactions. Thus, targeting Aβ clearance has now been considered a valid therapeutic approach for AD. Cellular uptake an
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::eebca8bee6ac5d37b918b471ce8bc117
https://doi.org/10.1021/acschemneuro.1c00209
https://doi.org/10.1021/acschemneuro.1c00209
Autor:
Xiaojuan, Wang, Yongqiang, Xue, Yang, Yao, Yang, Li, Xuefei, Ji, Tianyan, Chi, Peng, Liu, Libo, Zou
Publikováno v:
Neurochemistry International. 154:105298
Disrupted mitochondrial fission/fusion balance is consistently involved in neurodegenerative diseases, including Alzheimer's disease. PTEN-induced putative kinase 1 (PINK1), a mitochondrial kinase, has been reported to prevent mitochondrial injury, o
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4b7c3aa2e3723433ff07a50ada14e9e9
https://doi.org/10.1016/j.neuint.2022.105298
https://doi.org/10.1016/j.neuint.2022.105298
Publikováno v:
The journal of physiological sciences : JPS. 70(1)
Tolfenamic acid, a nonsteroidal anti-inflammatory drug, alleviated learning and memory deficits and decreased the expression of specificity protein 1 (SP1)-mediated cyclin-dependent kinase-5 (CDK5), a major protein kinase that regulates hyperphosphor
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::00a0acddde222878c2c79a7e7d8171ae
https://pubmed.ncbi.nlm.nih.gov/32517647
https://pubmed.ncbi.nlm.nih.gov/32517647
Autor:
Shaojie Wang, Ke Ying, Peng Liu, Tianyan Chi, Zhonggui He, Huimin Wang, Libo Zou, Xiaoyu Zhou, Zheng Liu, Xuefei Ji
Publikováno v:
Oxidative Medicine and Cellular Longevity, Vol 2020 (2020)
Oxidative Medicine and Cellular Longevity
Oxidative Medicine and Cellular Longevity
Diabetic nephropathy (DN) is a chronic diabetic microvascular complication. Hyperactivity of the polyol pathway is involved in the pathogenesis of DN. Aldose reductase (AR), the rate-limiting enzyme of the polyol pathway, is expected to be an effecti
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3f658229b5514844862f61e11a342469
https://doaj.org/article/94e30cea61f64f1287ae78b26c72d576
https://doaj.org/article/94e30cea61f64f1287ae78b26c72d576
Publikováno v:
Neurochemical Research. 43:1938-1946
Tolfenamic acid (TA), a nonsteroidal anti-inflammatory drug, shows neuroprotective effects and alleviates cognitive deficits in transgenic mouse models of Alzheimer's disease. However, whether TA can prevent the biochemical alterations induced by int
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ffa1d3b95e48bf6eca3aa86111fe4875
https://doi.org/10.1007/s11064-018-2615-7
https://doi.org/10.1007/s11064-018-2615-7
Publikováno v:
European Journal of Pharmacology. 820:18-30
Xanthoceraside, a novel triterpenoid saponin extracted from the husks of Xanthoceras sorbifolia Bunge, has neuroprotective effects in vivo and anti-inflammatory properties in vitro. However, the exact mechanism of xanthoceraside on anti-amyloid beta
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::d6442fbd1f70ddc7cb85d8dd78e52ca9
https://doi.org/10.1016/j.ejphar.2017.11.045
https://doi.org/10.1016/j.ejphar.2017.11.045
Autor:
Lei Yang, Libo Zou, Xiaoli Guo, Peng Liu, Tianyan Chi, Danyang Liu, Lin Zhu, Xuemei Zhao, Xuefei Ji
Publikováno v:
Psychopharmacology. 235:337-349
Alzheimer’s disease (AD) is characterized by memory loss and synaptic damage. Previous studies suggested that xanthoceraside decreases glutamate-induced PC12 cell death, ameliorates memory deficits, and increases the number of dendritic spines in A
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c62cf265c560ad5e0ce1487ca2ce9e0c
https://doi.org/10.1007/s00213-017-4775-6
https://doi.org/10.1007/s00213-017-4775-6
Publikováno v:
Journal of the Neurological Sciences. 376:166-175
Sigma-1 receptor (σ1r) activation could attenuate the learning and memory deficits in the AD model, ischemia model and others. In our previous study, the activation of σ1r increased the expression of brain-derived neurotrophic factor (BDNF), possib
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4fc087d37cd1e9e0cc3cef7424056454
https://doi.org/10.1016/j.jns.2017.03.027
https://doi.org/10.1016/j.jns.2017.03.027
Publikováno v:
Phytomedicine. 25:15-24
X. sorbifolia is a widely cultivated ecologicalcrop in the north of China which is used to produce biodiesel fuel. It also possesses special medicinal value and has attracted keen interests of researchers to explore its bioactivity.To extract the tot
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::777399560f2e0daa8a7f19952dbe19e7
https://doi.org/10.1016/j.phymed.2016.12.009
https://doi.org/10.1016/j.phymed.2016.12.009