Zobrazeno 1 - 9
of 9
pro vyhledávání: '"Tiantong Ou"'
Autor:
Tiantong Ou, Wenlong Yang, Wenjia Li, Yijing Lu, Zheng Dong, Hongming Zhu, Xiaolei Sun, Zhen Dong, Xinyu Weng, Suchi Chang, Hua Li, Yufan Li, Zhiwei Qiu, Kai Hu, Aijun Sun, Junbo Ge
Publikováno v:
Clinical and Translational Medicine, Vol 10, Iss 5, Pp n/a-n/a (2020)
Abstract Background Mesenchymal stem cells (MSCs) have therapeutic potential for multiple ischemic diseases. However, in vitro expansion of MSCs before clinical application leads to metabolic reprogramming from glycolysis to oxidative phosphorylation
Externí odkaz:
https://doaj.org/article/4670363919264368a6c97bc376313f73
Autor:
Lulu Shen, Yan Yang, Tiantong Ou, Chia-Chi C. Key, Sarah H. Tong, Russel C. Sequeira, Jonathan M. Nelson, Yan Nie, Zhan Wang, Elena Boudyguina, Swapnil V. Shewale, Xuewei Zhu
Publikováno v:
Journal of Lipid Research, Vol 58, Iss 9, Pp 1808-1821 (2017)
Dietary PUFAs reduce atherosclerosis and macrophage inflammation, but how nucleotide-binding oligomerization domain leucine-rich repeat-containing receptor protein (NLRP3) inflammasome activation and autophagy influence PUFA-mediated atheroprotection
Externí odkaz:
https://doaj.org/article/133f49da41464e73a54b24cfb467138e
Autor:
Suchi Chang, Jian Wu, Jifu Jin, Huairui Shi, Rifeng Gao, Xiao Li, Daile Jia, Xiaolei Sun, Tiantong Ou, Ji’e Yang, Aijun Sun, Junbo Ge
Publikováno v:
Oxidative Medicine and Cellular Longevity. 2022:1-15
Pulmonary hypertension (PH) is caused by chronic hypoxia that induces the migration and proliferation of pulmonary arterial smooth muscle cells (PASMCs), eventually resulting in right heart failure. PH has been related to aberrant autophagy; however,
Autor:
Manal Zabalawi, Russel C. Sequeira, Yan Nie, Xuewei Zhu, Elena Boudyguina, Tiantong Ou, Jennifer H. Madenspacher, Qingxia Zhao, Zhan Wang, Jonathan M. Nelson, Michael B. Fessler
Publikováno v:
Atherosclerosis
Background and aims Dietary long-chain (≥20 carbons) n-3 polyunsaturated fatty acids (PUFAs) reduce atherosclerosis and enhance macrophage autophagy activation. How macrophage autophagy impacts atherosclerotic progression, particularly when compari
Autor:
Junbo Ge, Wenlong Yang, Shuning Zhang, Yunzeng Zou, Hao Jiang, Juying Qian, Jianbing Zhu, Daile Jia, Zhiyong Qi, Tiantong Ou, Aijun Sun
Publikováno v:
Journal of Molecular and Cellular Cardiology. 134:119-130
Trimethylamine N-oxide (TMAO), a gut microbe-derived metabolite of dietary choline and other trimethylamine-containing nutrients, has been associated with poor prognosis in coronary heart disease. However, the role and underlying mechanisms of TMAO i
Autor:
Wenlong Yang, Zhiwei Qiu, Kai Hu, Yufan Li, Zhen Dong, Hongming Zhu, Aijun Sun, Xinyu Weng, Zheng Dong, Junbo Ge, Suchi Chang, Yijing Lu, Wenjia Li, Hua Li, Tiantong Ou, Xiaolei Sun
Publikováno v:
Clinical and Translational Medicine
Clinical and Translational Medicine, Vol 10, Iss 5, Pp n/a-n/a (2020)
Clinical and Translational Medicine, Vol 10, Iss 5, Pp n/a-n/a (2020)
Background Mesenchymal stem cells (MSCs) have therapeutic potential for multiple ischemic diseases. However, in vitro expansion of MSCs before clinical application leads to metabolic reprogramming from glycolysis to oxidative phosphorylation, drastic
Autor:
Shaofeng Guan, Wei-Yi Fang, Jianwei Ma, Wenzheng Han, Ping Yang, Ruo-Gu Li, Shuping Wang, Xu-Min Hou, Min Zhang, Zhicheng Pan, Xin-Kai Qu, Hua Liu, Tiantong Ou
Publikováno v:
Molecular and Cellular Biochemistry. 437:45-53
Endothelial inflammation and monocyte plays an essential role in the initiation and progression of atherosclerosis. Ghrelin is beneficial for atherosclerosis progression. However, the detailed and precise molecular mechanisms of how ghrelin regulates
Autor:
Zhiyong Qi, Junbo Ge, Hao Jiang, Juying Qian, Tiantong Ou, Daile Jia, Shuning Zhang, Wenlong Yang, Yunzeng Zou, Aijun Sun
Publikováno v:
Cell Proliferation
Objective Adipose‐derived mesenchymal stem cells (ADSCs) offer great promise as cell therapy for ischaemic diseases. Due to their poor survival in the ischaemic environment, the therapeutic efficacy of ADSCs is still relatively low. Interleukin‐1
Autor:
Min Zhang, Shaofeng Guan, Xin-Kai Qu, Ruo-Gu Li, Tiantong Ou, Xu-Min Hou, Wenzheng Han, Jinjie Dai, Wenxia Wang
Publikováno v:
Natural Product Research. 30:1240-1247
An integration of virtual screening and kinase assay was reported to identify AMPK kinase inhibitors from various natural medicines.The activation of AMP-activated protein kinase (AMPK) signalling pathway plays a central role in the pathologic progre