Zobrazeno 1 - 10
of 98
pro vyhledávání: '"Tiantai, Zhang"'
Publikováno v:
Acta Pharmaceutica Sinica B, Vol 13, Iss 10, Pp 4185-4201 (2023)
Monocytes are key effectors in autoimmunity-related diseases in the central nervous system (CNS) due to the critical roles of these cells in the production of proinflammatory cytokines, differentiation of T-helper (Th) cells, and antigen presentation
Externí odkaz:
https://doaj.org/article/f2d2564b1d84477dbba54b4abba92457
Autor:
Gaona Shi, Yu Zhou, Wenshuai Liu, Chengjuan Chen, Yazi Wei, Xinlong Yan, Lei Wu, Weiwei Wang, Lan Sun, Tiantai Zhang
Publikováno v:
Acta Pharmaceutica Sinica B, Vol 13, Iss 6, Pp 2778-2794 (2023)
Tolerogenic dendritic cells (tolDCs) facilitate the suppression of autoimmune responses by differentiating regulatory T cells (Treg). The dysfunction of immunotolerance results in the development of autoimmune diseases, such as rheumatoid arthritis (
Externí odkaz:
https://doaj.org/article/29fdddd46e6440ee884d46b379a326f3
Publikováno v:
Acta Pharmaceutica Sinica B, Vol 10, Iss 10, Pp 1954-1965 (2020)
Three new C20-diterpenoid alkaloids with a sulfonic acid unit, named aconicarmisulfonines B and C (1 and 2) and chuanfusulfonine A (3), respectively, were isolated from the Aconitum carmichaelii lateral roots (“fu zi” in Chinese). Structures of 1
Externí odkaz:
https://doaj.org/article/273cffdca2a34bd5963c92e3d1bec313
Autor:
Shuai Shao, Huan Xia, Min Hu, Chengjuan Chen, Junmin Fu, Gaona Shi, Qinglan Guo, Yu Zhou, Wenjie Wang, Jiangong Shi, Tiantai Zhang
Publikováno v:
Journal of Neuroinflammation, Vol 17, Iss 1, Pp 1-11 (2020)
Abstract Background Isotalatizidine is a representative C19-diterpenoid alkaloid extracted from the lateral roots of Aconitum carmichaelii, which has been widely used to treat various diseases on account of its analgesic, anti-inflammatory, anti-rheu
Externí odkaz:
https://doaj.org/article/2796c883d6434012a29172576a513aae
Autor:
Xiang Wang, Gaona Shi, Rao Wei, Meng Li, Qingyang Zhang, Tiantai Zhang, Chuan-Feng Chen, Hai-Yu Hu
Publikováno v:
Chemical Science; 5/7/2024, Vol. 15 Issue 17, p6421-6431, 11p
Autor:
Min Hu, Chengbo Xu, Chao Yang, Hongli Zuo, Chengjuan Chen, Dan Zhang, Gaona Shi, Wenjie Wang, Jiangong Shi, Tiantai Zhang
Publikováno v:
Journal of Experimental & Clinical Cancer Research, Vol 38, Iss 1, Pp 1-12 (2019)
Abstract Background The JAK2-STAT signaling pathway plays a critical role in myeloproliferative neoplasms (MPN). An activating mutation in JAK2 (V617F) is present in ~ 95% of polycythemia vera, essential thrombocythemia, and primary myelofibrosis cas
Externí odkaz:
https://doaj.org/article/392e6ca4521848d291b94432d3c713e2
Publikováno v:
Therapeutic Advances in Medical Oncology, Vol 13 (2021)
Background: Dendritic cells (DCs) are antigen-presenting cells that play a pivotal role in adaptive cell-mediated immunity by priming and activating T cells against specific tumour and pathogenic antigens. Methotrexate (MTX), a folate derivative, fun
Externí odkaz:
https://doaj.org/article/ebd509183ad54ec5bc144479e05b19ba
Publikováno v:
Evidence-Based Complementary and Alternative Medicine. 2023:1-10
Xuelian, as a traditional Chinese ethnodrug, plays an important role in anti-inflammation, immunoregulation, promoting blood circulation, and other physiological functions. It has been prepared into different traditional Chinese medicine preparations
Autor:
Qinglan Guo, Huan Xia, Xianhua Meng, Gaona Shi, Chengbo Xu, Chenggen Zhu, Tiantai Zhang, Jiangong Shi
Publikováno v:
Acta Pharmaceutica Sinica B, Vol 8, Iss 3, Pp 409-419 (2018)
Eight new C19-diterpenoid alkaloid arabinosides, named aconicarmichosides E–L (1–8), were isolated from an aqueous extract of the lateral roots of Aconitum carmichaelii (Fu Zi). Their structures were determined by spectroscopic and chemical metho
Externí odkaz:
https://doaj.org/article/217a9a9789a84828b1249e962cd5faee
Publikováno v:
Chinese Chemical Letters. 33:5047-5050