Zobrazeno 1 - 10
of 211
pro vyhledávání: '"Tianru, Jin"'
Autor:
Juan Pang, Fitore Raka, Alya Abbas Heirali, Weijuan Shao, Dinghui Liu, Jianqiu Gu, Jia Nuo Feng, Chieko Mineo, Philip W. Shaul, Xiaoxian Qian, Bryan Coburn, Khosrow Adeli, Wenhua Ling, Tianru Jin
Publikováno v:
Nature Communications, Vol 14, Iss 1, Pp 1-18 (2023)
Abstract Two common features of dietary polyphenols have hampered our mechanistic understanding of their beneficial effects for decades: targeting multiple organs and extremely low bioavailability. We show here that resveratrol intervention (REV-I) i
Externí odkaz:
https://doaj.org/article/7768586838704f1f9466b8b884b7e232
Publikováno v:
Indian Journal of Ophthalmology, Vol 71, Iss 8, Pp 2967-2971 (2023)
Purpose: To evaluate whether the toric intra-ocular lens (IOL) power calculation based on total corneal astigmatism (TCA) in eyes with high posterior corneal astigmatism (PCA) could result in a systematic over-correction or under-correction after ope
Externí odkaz:
https://doaj.org/article/516e5bc6187c465eb203b74d7371617f
Publikováno v:
Indian Journal of Ophthalmology, Vol 71, Iss 2, Pp 541-546 (2023)
Purpose: To evaluate a method using measured values of total corneal refractive power (TCRP) for a manufacturer's online calculator by comparing it with the Barrett toric calculator (BTC) and Kane toric calculator (KTC) combined with simulated kerato
Externí odkaz:
https://doaj.org/article/1a34e9a8e73c4a76b1d4d0a8440d2b1c
Publikováno v:
Acta Pharmaceutica Sinica B, Vol 12, Iss 11, Pp 4040-4055 (2022)
Since 2005, GLP-1 receptor (GLP-1R) agonists (GLP-1RAs) have been developed as therapeutic agents for type 2 diabetes (T2D). GLP-1R is not only expressed in pancreatic islets but also other organs, especially the lung. However, controversy on extra-p
Externí odkaz:
https://doaj.org/article/28d296c401754620b0fad65b1fcbbc17
Publikováno v:
Acta Pharmaceutica Sinica B, Vol 13, Iss 4, Pp 1786-1788 (2023)
Externí odkaz:
https://doaj.org/article/b2169093a5a74133bc1355af94ac9a71
Publikováno v:
Physiological Reports, Vol 11, Iss 5, Pp n/a-n/a (2023)
Abstract Metabolic functions of GLP‐1 and its analogues have been extensively investigated. In addition to acting as an incretin and reducing body weight, we and others have suggested the existence of GLP‐1/fibroblast growth factor 21 (FGF21) axi
Externí odkaz:
https://doaj.org/article/e5f075302aaf4baab111b0a93f831b10
Autor:
Weijuan Shao, Tianru Jin
Publikováno v:
Chronic Diseases and Translational Medicine, Vol 8, Iss 1, Pp 19-25 (2022)
Abstract Fibroblast growth factor 21 (FGF21) is a fasting or stress inducible metabolic hormone produced mainly in the liver. It plays important roles in regulating both glucose and lipid homeostasis via interacting with a heterodimeric receptor comp
Externí odkaz:
https://doaj.org/article/27e3ef2d2bfa4ae4bb0e6fbc8665bac5
Autor:
Xin Dai, Ruyi Liao, Chaoqun Liu, Si Liu, Haiyan Huang, Jianjun Liu, Tianru Jin, Honghui Guo, Zhihua Zheng, Min Xia, Wenhua Ling, Yunjun Xiao
Publikováno v:
Redox Biology, Vol 45, Iss , Pp 102033- (2021)
S-adenosylhomocysteine (SAH) is hydrolyzed by SAH hydrolase (SAHH) to homocysteine and adenosine. Increased plasma SAH levels were associated with disturbed renal function in patients with diabetes. However, the role and mechanism of SAHH in diabetic
Externí odkaz:
https://doaj.org/article/1b03154480da4db0b3b157ae577b9896
Autor:
Junling Liu, Kun Yang, Jin Yang, Wenhua Xiao, Yunyi Le, Fei Yu, Liangbiao Gu, Shan Lang, Qing Tian, Tianru Jin, Rui Wei, Tianpei Hong
Publikováno v:
EBioMedicine, Vol 41, Iss , Pp 73-84 (2019)
Background: Glucagon-like peptide-1 (GLP-1) and its based agents improve glycemic control. Although their attenuating effect on hepatic glucose output has drawn our attention for decades, the potential mechanisms remain unclear. Methods: Cytokine arr
Externí odkaz:
https://doaj.org/article/deb5287b2ca74252900c25803e37dc43
Publikováno v:
Journal of Molecular Endocrinology. 69:343-356
Although canonical Wnt signaling pathway activation was shown to negatively regulate adipogenesis, recent investigations suggest that Wnt pathway effectors TCF7L2 and β-catenin (β-cat) in adipose tissues are also involved in energy homeostasis duri