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Akademický článek

Mesenchymal stromal cell treatment attenuates repetitive mild traumatic brain injury-induced persistent cognitive deficits via suppressing ferroptosis

Autor: Dong Wang, Shishuang Zhang, Xintong Ge, Zhenyu Yin, Meimei Li, Mengtian Guo, Tianpeng Hu, Zhaoli Han, Xiaodong Kong, Dai Li, Jing Zhao, Lu Wang, Qiang Liu, Fanglian Chen, Ping Lei

Publikováno v: Journal of Neuroinflammation, Vol 19, Iss 1, Pp 1-19 (2022)

Abstract The incidence of repetitive mild traumatic brain injury (rmTBI), one of the main risk factors for predicting neurodegenerative disorders, is increasing; however, its underlying mechanism remains unclear. As suggested by several studies, ferr

Externí odkaz: https://doaj.org/article/c7fbf3aa73124603aebc9300b6ed6d56

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Akademický článek

Research advances in the study of sleep disorders, circadian rhythm disturbances and Alzheimer’s disease

Autor: Xiangyang Xiong, Tianpeng Hu, Zhenyu Yin, Yaodan Zhang, Fanglian Chen, Ping Lei

Publikováno v: Frontiers in Aging Neuroscience, Vol 14 (2022)

Although there are still no satisfactory answers to the question of why we need to sleep, a better understanding of its function will help to improve societal attitudes toward sleep. Sleep disorders are very common in neurodegenerative diseases and a

Externí odkaz: https://doaj.org/article/963c585f185d44e39964cf47003a3624

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Akademický článek

Intranasal Delivery of Gene-Edited Microglial Exosomes Improves Neurological Outcomes after Intracerebral Hemorrhage by Regulating Neuroinflammation

Autor: Mengtian Guo, Xintong Ge, Conglin Wang, Zhenyu Yin, Zexi Jia, Tianpeng Hu, Meimei Li, Dong Wang, Zhaoli Han, Lu Wang, Xiangyang Xiong, Fanglian Chen, Ping Lei

Publikováno v: Brain Sciences, Vol 13, Iss 4, p 639 (2023)

Neural inflammatory response is a crucial pathological change in intracerebral hemorrhage (ICH) which accelerates the formation of perihematomal edema and aggravates neural cell death. Although surgical and drug treatments for ICH have advanced rapid

Externí odkaz: https://doaj.org/article/72d0cacc946c4acc9487941b1ca7abd3

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Akademický článek

Modafinil Reduces Neuronal Pyroptosis and Cognitive Decline After Sleep Deprivation

Autor: Xiangyang Xiong, Yan Zuo, Lu Cheng, Zhenyu Yin, Tianpeng Hu, Mengtian Guo, Zhaoli Han, Xintong Ge, Wenzhu Li, Yan Wang, Dong Wang, Conglin Wang, Lan Zhang, Yaodan Zhang, Qiang Liu, Fanglian Chen, Ping Lei

Publikováno v: Frontiers in Neuroscience, Vol 16 (2022)

Sleep deprivation (SD) induces systemic inflammation that promotes neuronal pyroptosis. The purpose of this study was to investigate the effect of an antioxidant modafinil on neuronal pyroptosis and cognitive decline following SD. Using a mouse model

Externí odkaz: https://doaj.org/article/309d55d452664c4dafc61f1a05d64ee4

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Akademický článek

Inhibition of Exosome Release Alleviates Cognitive Impairment After Repetitive Mild Traumatic Brain Injury

Autor: Tianpeng Hu, Zhaoli Han, Xiangyang Xiong, Meimei Li, Mengtian Guo, Zhenyu Yin, Dong Wang, Lu Cheng, Dai Li, Shishuang Zhang, Lu Wang, Jing Zhao, Qiang Liu, Fanglian Chen, Ping Lei

Publikováno v: Frontiers in Cellular Neuroscience, Vol 16 (2022)

BackgroundRepetitive mild traumatic brain injury (rmTBI) is closely associated with chronic traumatic encephalopathy (CTE). Neuroinflammation and neuropathological protein accumulation are key links to CTE progression. Exosomes play important roles i

Externí odkaz: https://doaj.org/article/c9e6c5ef0baf44b48b50653e3b52a273

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Akademický článek

Health Risks Associated with Polycyclic Aromatic Hydrocarbons (PAHs) in Dustfall Collected from Universities in Wuhan, China

Autor: Ying Liu, Yao Mao, Jun Xu, Wenmin Chen, Tianpeng Hu, Chengyan Xu, Weijie Liu, Chengkai Qu, Wei Chen, Jiaquan Zhang, Xinli Xing, Shihua Qi

Publikováno v: Atmosphere, Vol 13, Iss 10, p 1707 (2022)

Atmospheric dustfall samples from the libraries and dormitories of 14 universities in Wuhan, China, were collected and analyzed for 16 priority polycyclic aromatic hydrocarbons (PAHs). The results showed that the levels of Σ16PAHs in the dustfall fr

Externí odkaz: https://doaj.org/article/9af7988062364cec92974afec21281fc

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Akademický článek

Sleep Quality of Patients with Differentiated Thyroid Cancer.

Publikováno v: PLoS ONE, Vol 10, Iss 6, p e0130634 (2015)

We aimed to measure prevalence of sleep disturbance in patients with differentiated thyroid cancer (DTC) by calculating Pittsburgh Sleep Quality Index (PSQI), and compare these data with patients with benign thyroid nodules or normal participants.Thr

Externí odkaz: https://doaj.org/article/6f1446e3092c4b528c35b4f19f13aba7

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