Zobrazeno 1 - 10
of 28
pro vyhledávání: '"Tianming Lü"'
Autor:
Shiqi Yuan, Huan Li, Canhong Yang, Wenyi Xie, Yuanyuan Wang, Jiafa Zhang, Zibo cai, Zhenlin Mao, Weibing Xie, Tianming Lü
Publikováno v:
Biomedicine & Pharmacotherapy, Vol 126, Iss , Pp 110102- (2020)
Monocytes play a crucial role in Alzheimer's disease (AD), and docosahexaenoic acid (DHA) has a neuroprotective effect for many neurodegenerative diseases. However, mechanisms that regulate monocyte and Aβ protein interaction in AD and the effects o
Externí odkaz:
https://doaj.org/article/cb5d18c17c36418b92d17efeba56ae01
Autor:
Jun Li, Qiang Zhang, Hao Yang, Wenli Lu, Yulong Fu, Yingcai Xiong, Xuan Wang, Tianming Lu, Yanlin Xin, Zejuan Xie, Weichao Chen, Guoqiang Wang, Yuanyuan Guo, Ruogu Qi
Publikováno v:
Acta Pharmaceutica Sinica B, Vol 14, Iss 7, Pp 3251-3265 (2024)
Selective activation of Pt(IV) prodrugs within tumors has emerged as a promising strategy in tumor treatment. Although progress has been made with photo- and ultrasound-activated Pt(IV) prodrugs, concerns remain over the non-specific activation of ph
Externí odkaz:
https://doaj.org/article/83997a39c44b49ab992d1914722dd2a8
Autor:
Yunzhu Yang, Jiafa Zhang, Canhong Yang, Bo Dong, Yanhong Fu, Yuanyuan Wang, Ming Gong, Tao Liu, Pingming Qiu, Weibing Xie, Tianming Lü
Publikováno v:
Brain Research. 1801:148206
The neuroinflammatory hypothesis of Alzheimer's disease (AD) posits that amyloid-beta (Aβ) phagocytosis along with subsequent lysosomal damage and NLRP3 inflammasome activation plays important roles in Aβ-induced microglia activation and microglia-
Autor:
Ruogu Qi, Shanshan Wang, Jiayi Yu, Tianming Lu, Zhiqiang Bi, Weibo Liu, Yuanyuan Guo, Yong Bian, Jianliang Shen, Xuesong Zhang, Wenhao Hu
Publikováno v:
Engineering, Vol 36, Iss , Pp 178-192 (2024)
Multiple myeloma (MM) is the second most prevalent hematological malignancy. Current MM treatment strategies are hampered by systemic toxicity and suboptimal therapeutic efficacy. This study addressed these limitations through the development of a po
Externí odkaz:
https://doaj.org/article/13a6ddea0c2c4f81b45d1ccb5fbb0539
Autor:
Tianming Lu, Lirun Zhou, Zheng Chu, Yang Song, Qixin Wang, Minghong Zhao, Chuanhao Dai, Lin Chen, Guangqing Cheng, Jigang Wang, Qiuyan Guo
Publikováno v:
Chinese Medicine, Vol 19, Iss 1, Pp 1-14 (2024)
Abstract Objective To determine the pharmacodynamic mechanism underlying Cordyceps sinensis relief in a murine model of non-small cell lung cancer (NSCLC). Methods We created a murine model of NSCLC and studied the potential molecular mechanism by wh
Externí odkaz:
https://doaj.org/article/8efdef8686cf4f37ad1ebdb6886e65ce
Autor:
Tianming Lu, Zixian Liu, Ruoning Qian, Yitian Zhou, Jun Li, Qiang Zhang, Hao Yang, Wenli Lu, Yanlin Xin, Zejuan Xie, Lesan Yan, Shanshan Wang, Ruogu Qi, Zhengguang Zhang
Publikováno v:
Materials Today Bio, Vol 29, Iss , Pp 101270- (2024)
Sorafenib (SF), a multi-targeted tyrosine kinase inhibitor, serves as a primary therapeutic modality for advanced liver cancer. Nonetheless, its clinical efficacy is hindered by various obstacles, such as limited bioavailability and inadequate accumu
Externí odkaz:
https://doaj.org/article/9ca1bc3259a74ed3991cbac7f70af336
Publikováno v:
Journal of healthcare engineering. 2022
Protein misfolding and/or aggregation are common pathological features associated with a number of neurodegenerative diseases, including Alzheimer’s disease (AD) and Parkinson disease (PD). Abnormal protein aggregation may be caused by misfolding o
Publikováno v:
International Journal of Electrical Power & Energy Systems, Vol 158, Iss , Pp 109911- (2024)
The correct identification of partial discharges (PDs) is instrumental for the maintenance plan in gas-insulated systems (GIS). However, onsite PD measurements are difficult, especially in HVDC systems, where partial discharges can be confused with i
Externí odkaz:
https://doaj.org/article/a49e8b2cdfc049f3a401f40885776691
Autor:
Wei-Bing Xie, Enping Huang, Tianming Lü, Jiashun Liao, Ruimei Zhou, Dunpeng Cai, Shi-You Chen, Qin Tian
Publikováno v:
The FASEB Journal. 35
Renal interstitial fibrosis (RIF) is a pathological process that fibrotic components are excessively deposited in the renal interstitial space due to kidney injury, resulting in impaired renal function and chronic kidney disease. The molecular mechan
Autor:
Shuyu Zheng, Yanlin Xin, Jiamin Lin, Zejuan Xie, Keyu Cheng, Shanshan Wang, Wenli Lu, Hao Yang, Tianming Lu, Jun Li, Ruogu Qi, Yuanyuan Guo
Publikováno v:
Journal of Pharmaceutical Analysis, Vol 14, Iss 1, Pp 152-155 (2024)
Externí odkaz:
https://doaj.org/article/565eba4159814c05a616f943ae1b1858