Zobrazeno 1 - 10
of 36
pro vyhledávání: '"Tianling Hu"'
Publikováno v:
Frontiers in Pharmacology, Vol 14 (2023)
Introduction: Adverse drug reactions (ADR) are directly related to public health and become the focus of public and media attention. At present, a large number of ADR events have been reported on the Internet, but the mining and utilization of such i
Externí odkaz:
https://doaj.org/article/b7d0ffcf251b4090ad3b8fe659444244
Autor:
Shoumin Zhu, Marwah Al-Mathkour, Longlong Cao, Shayan Khalafi, Zheng Chen, Julio Poveda, Dunfa Peng, Heng Lu, Mohammed Soutto, Tianling Hu, Oliver G. McDonald, Alexander Zaika, Wael El-Rifai
Publikováno v:
Cell Reports, Vol 42, Iss 1, Pp 112005- (2023)
Summary: Infection with Helicobacter pylori (H. pylori) is the main risk factor for gastric cancer, a leading cause of cancer-related death worldwide. The oncogenic functions of cyclin-dependent kinase 1 (CDK1) are not fully understood in gastric tum
Externí odkaz:
https://doaj.org/article/692c8711cb8640889db364be69705399
Autor:
Farah Ballout, Heng Lu, Zheng Chen, Tianling Hu, Lei Chen, Mary Kay Washington, Wael El-Rifai, Dunfa Peng
Publikováno v:
Antioxidants, Vol 11, Iss 10, p 1859 (2022)
Esophageal adenocarcinoma (EAC), the predominant type of esophageal cancer in the United States, develops through Barrett’s esophagus (BE)-dysplasia-carcinoma cascade. Gastroesophageal reflux disease, where acidic bile salts refluxate into the esop
Externí odkaz:
https://doaj.org/article/f10132b013984b8c921edbc89ac1a501
Autor:
Marwah M. Al-Mathkour, Shoumin Zhu, Longlong Cao, Shayan Khalafi, Zheng Chen, Julio Poveda, Dunfa Peng, Heng Lu, Mohammed Soutto, Tianling Hu, Oliver McDonalnd, Alexander Zaika, Wael El-Rifai
Publikováno v:
Cancer Research. 83:5972-5972
Background: Cell cycle dysregulation is a hallmark of cancer, resulting in unregulated cell proliferation and, eventually, tumor development. Cyclin-dependent kinase 1 (CDK1) is a cell cycle regulatory protein that is involved in cell cycle maintenan
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::016185a4feff3a7528c4654efff5162a
https://doi.org/10.1158/1538-7445.am2023-5972
https://doi.org/10.1158/1538-7445.am2023-5972
Autor:
Heng Lu, Ahmed Gomaa, Lihong Wang-Bishop, Farah Ballout, Tianling Hu, Oliver McDonald, Mary Kay Washington, Alan S. Livingstone, Timothy C. Wang, Dunfa Peng, Wael El-Rifai, Zheng Chen
Publikováno v:
Cancers; Volume 14; Issue 6; Pages: 1401
Unfolded protein response (UPR) protects malignant cells from endoplasmic reticulum stress-induced apoptosis. We report that Aurora kinase A (AURKA) promotes cancer cell survival by activating UPR in esophageal adenocarcinoma (EAC). A strong positive
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e2943d630f3b4d8aafac928bd4fa9b39
Autor:
Heng Lu, Tianling Hu, Alexander Zaika, Zheng Chen, Dunfa Peng, Wael El-Rifai, Zhangjian Zhou, Shoumin Zhu
Publikováno v:
Cancer Lett
Gastroesophageal reflux disease (GERD) is the main risk factor for Barrett's tumorigenesis. In this study, we investigated the role of NRF2 in response to exposure to acidic bile salts (ABS), in conditions that mimic GERD, using Barrett's esophagus c
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::791d455d7b46db869abd8e8fa3c40c85
https://doi.org/10.1016/j.canlet.2019.05.031
https://doi.org/10.1016/j.canlet.2019.05.031
Publikováno v:
Cancer Research. 82:5407-5407
Background: The incidence rate of the esophageal adenocarcinoma (EAC) has increased rapidly among men during the past four decades in the USA and western countries while the 5 year survival rate is still below 20%. Traditional chemotherapy is still t
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::e18508a8ba2d85a200156f1763c9be9f
https://doi.org/10.1158/1538-7445.am2022-5407
https://doi.org/10.1158/1538-7445.am2022-5407
Publikováno v:
Cancers
Simple Summary Esophageal adenocarcinoma has become a major clinical challenge in the western world due to its rapid increasing incidence and poor overall prognosis. Understanding the molecular events of its tumorigenesis is the key to better diagnos
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::30b6bc2a29ab36e0861a80328c9ef1a9
https://pubmed.ncbi.nlm.nih.gov/32927604
https://pubmed.ncbi.nlm.nih.gov/32927604
Publikováno v:
Cancers
Volume 12
Issue 9
Cancers, Vol 12, Iss 2573, p 2573 (2020)
Volume 12
Issue 9
Cancers, Vol 12, Iss 2573, p 2573 (2020)
The incidence of esophageal adenocarcinoma (EAC) has been rising dramatically in the past few decades in the United States and Western world. The N-myc downregulated gene 4 (NDRG4) belongs to the human NDRG family. In this study, we aimed to identify
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::66c23f61748c0e15c60cf1824d27861a
https://doi.org/10.3390/cancers12092573
https://doi.org/10.3390/cancers12092573
Publikováno v:
Cancer Research. 80:1938-1938
Background: The incidence of esophageal adenocarcinoma (EAC) has rising rapidly in the US and western countries during past three decades. However, it remains very lethal disease with an overall five-year survival rate less than 20%, due to later sta
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::a6c7b0b1d4b960d46da136838db4cb8c
https://doi.org/10.1158/1538-7445.am2020-1938
https://doi.org/10.1158/1538-7445.am2020-1938