Zobrazeno 1 - 10
of 26
pro vyhledávání: '"Tianling Chen"'
Autor:
Mayur Narkhede, Nancy L. Bartlett, Sami Ibrahimi, Leslie Popplewell, Anna Seto, Jamie Bates, Yeonju Lee, Vaishnavi Ganti, Ling Han, Tianling Chen, Manish R. Patel
Publikováno v:
eJHaem, Vol 4, Iss 2, Pp 370-380 (2023)
Abstract Signal regulatory protein alpha (SIRPα) is the receptor for cluster of differentiation (CD)47, a potent “don't eat me” signal for macrophages. Disruption of CD47‐SIRPα signaling in the presence of prophagocytic signals can lead to en
Externí odkaz:
https://doaj.org/article/8470c6427c364eb6b41fe36383a68d9f
Autor:
Michael Gordon, Anthony W Tolcher, James Strauss, Marianna Zavodovskaya, Anna Seto, Tianling Chen, Susanna Stinson, Kathleen M Mahoney, Chia-Hsiang Hsueh, Shuyan Zhai, Thomas Tarnowski, Juliane M Jürgensmeier, Ahmed A Othman
Publikováno v:
Journal for ImmunoTherapy of Cancer, Vol 11, Iss 2 (2023)
Background Cluster of differentiation (CD)73-adenosine and transforming growth factor (TGF)-β pathways are involved in abrogated antitumor immune responses and can lead to protumor conditions. This Phase 1 study (NCT03954704) evaluated the safety, p
Externí odkaz:
https://doaj.org/article/5b53ab91d2af465c92d22787a41dbfa2
Autor:
Wendie Zhou, Lili Yu, Yuying Fan, Baisheng Shi, Xiaohui Wang, Tianling Chen, Haixia Yu, Jie Liu, Xizhen Wang, Caihong Liu, Huijia Zheng
Publikováno v:
PLoS ONE, Vol 17, Iss 5, p e0268599 (2022)
AimThe study aimed to investigate the effect of early mobilization combined with early nutrition (EMN) on intensive care unit-acquired weakness (ICU-AW) in intensive care unit (ICU) settings compared with early mobilization (EM) or routine care.Metho
Externí odkaz:
https://doaj.org/article/34b59ebf5efc4a0f83408fe018ed948f
Autor:
Michael Gordon, Anthony Tolcher, James Strauss, Rick Sorensen, Marianna Zavodovskaya, Ping Cheng Yi, Audrey Goddard, Matthew Peach, Kathleen Mahoney, Xiaoyun Yang, Kai-Wen Lin, Biao Li, Anna Seto, Tianling Chen, Juliane Jürgensmeier
Publikováno v:
Journal for ImmunoTherapy of Cancer, Vol 9, Iss Suppl 2 (2021)
Externí odkaz:
https://doaj.org/article/347886e0b29943a29b63e012d170d625
Autor:
Jeffrey E. Lancet, Gail J. Roboz, Larry D. Cripe, Glenn C. Michelson, Judith A. Fox, Richard D. Leavitt, Tianling Chen, Rachael Hawtin, Adam R. Craig, Farhad Ravandi, Michael B. Maris, Robert K. Stuart, Judith E. Karp
Publikováno v:
Haematologica, Vol 100, Iss 2 (2015)
Vosaroxin is a first-in-class anticancer quinolone derivative that intercalates DNA and inhibits topoisomerase II. This study assessed the safety and tolerability of vosaroxin plus cytarabine in patients with relapsed/refractory acute myeloid leukemi
Externí odkaz:
https://doaj.org/article/93594ff6a8384901885ba68dd0e85326
Autor:
Zhongyi Liu, Tianling Chen, Jinpeng Li, Bin Liu, Yuxia Zhang, Yan Liu, Xiaoge Niu, Misbha Rafiq Khan
Publikováno v:
CrystEngComm. 23:3185-3195
Using asymmetric 2-chloro-4-ferrocenylbenzoic acid, six new complexes formulated as {[Mn(OOCClH3C6Fc)2(H2O)3]·(CH3OH)}n (1), {[Ni(OOCClH3C6Fc)2(H2O)3](CH3OH)}n (2), [Co(OOCClH3C6Fc)2(H2O)3]n (3), [Co(η2-OOCClH3C6Fc)(fcz)]2·CH3OH (4) [Hfcz = a-(2,4
Autor:
Anthony W Tolcher, Michael Gordon, Kathleen M Mahoney, Anna Seto, Marianna Zavodovskaya, Chia-Hsiang Hsueh, Shuyan Zhai, Thomas Tarnowski, Juliane M Jürgensmeier, Susanna Stinson, Ahmed A Othman, Tianling Chen, James Strauss
Publikováno v:
Journal for ImmunoTherapy of Cancer. 11:e005267
BackgroundCluster of differentiation (CD)73-adenosine and transforming growth factor (TGF)-β pathways are involved in abrogated antitumor immune responses and can lead to protumor conditions. This Phase 1 study (NCT03954704) evaluated the safety, ph
Autor:
Kathleen M. Mahoney, Audrey Goddard, Matthew Peach, Marianna Zavodovskaya, Michael S. Gordon, Rick Sorensen, James Strauss, Kai-Wen Lin, Xiaoyun Yang, Tianling Chen, Juliane Jürgensmeier, Anna Seto, Anthony W. Tolcher, Ping Cheng Yi, Biao Li
Publikováno v:
Journal for ImmunoTherapy of Cancer, Vol 9, Iss Suppl 2 (2021)
BackgroundGS-1423 is a first-in-class bifunctional molecule comprised of an anti-CD73 antibody fused to the extracellular domain of TGFβ receptor II (TGFβRII). GS-1423 is designed to inhibit CD73-mediated adenosine production and neutralize active
Publikováno v:
Adipocyte, Vol 12, Iss 1 (2023)
ABSTRACTThe healing of skin wounds is a highly coordinated multi-step process that occurs after trauma including surgical incisions, thermal burns, and chronic ulcers. In this study, the authors investigated lncRNA FOXD2-AS1 function in adipose mesen
Externí odkaz:
https://doaj.org/article/2b2b31181a3545a6be60a2430693cf71
Autor:
Glenn Michelson, Larry D. Cripe, Gail J. Roboz, Judith E. Karp, Farhad Ravandi, Jeffrey E. Lancet, Richard D. Leavitt, Rachael E. Hawtin, Tianling Chen, Adam R. Craig, Robert K. Stuart, Michael B. Maris, Judith A. Fox
Publikováno v:
Haematologica. 100:231-237
Vosaroxin is a first-in-class anticancer quinolone derivative that intercalates DNA and inhibits topoisomerase II. This study assessed the safety and tolerability of vosaroxin plus cytarabine in patients with relapsed/refractory acute myeloid leukemi