Zobrazeno 1 - 6
of 6
pro vyhledávání: '"Tianli Xie"'
Publikováno v:
Frontiers in Medicine, Vol 10 (2023)
BackgroundBispectral index (BIS), an index used to monitor the depth of anesthesia, can be interfered with by the electromyogram (EMG) signal. The 95% spectral edge frequency (SEF95) also can reflect the sedation depth. Remimazolam in monitored anest
Externí odkaz:
https://doaj.org/article/1aed8c47b52b4fcd8f46a3575c0f72d3
Publikováno v:
IEEE Transactions on Neural Systems and Rehabilitation Engineering, Vol 30, Pp 2077-2087 (2022)
Investigating neural mechanisms of anesthesia process and developing efficient anesthetized state detection methods are especially on high demand for clinical consciousness monitoring. Traditional anesthesia monitoring methods are not involved with t
Externí odkaz:
https://doaj.org/article/aca2d281cf4e4ed287781186b708d203
Publikováno v:
2021 43rd Annual International Conference of the IEEE Engineering in Medicine & Biology Society (EMBC).
Increasingly, studies have shown that changes in brain network topology accompany loss of consciousness such that the functional connectivity of the prefrontal-parietal network differs significantly in anesthetized and awake states. In this work, ane
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a0f3408e9936b6515d47a307afda3b5e
https://doi.org/10.1109/embc46164.2021.9631095
https://doi.org/10.1109/embc46164.2021.9631095
Autor:
Jie, Yu, Xin, Chai, Jinping, Pang, Zhe, Wang, Hong, Zhao, Tianli, Xie, Lei, Xu, Rong, Sheng, Dan, Li, Su, Zeng, Tingjun, Hou, Yu, Kang
Publikováno v:
European Journal of Medicinal Chemistry. 242:114646
DNA methyltransferases (DNMTs) are important epigenetic regulatory enzymes involved in gene expression corresponding to many diseases including cancer. As one of the major enzymatically active mammalian DNMTs, DNMT3A has been regarded as an attractiv
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::782c13be3444f80a6cc63bc94d6c8746
https://doi.org/10.1016/j.ejmech.2022.114646
https://doi.org/10.1016/j.ejmech.2022.114646
Autor:
Shan Chang, Tingjun Hou, Ercheng Wang, Weitao Fu, Zhe Wang, Tianli Xie, Feng Zhu, Jie Yu, Lei Xu, Yu Kang, Su Zeng
Publikováno v:
Physical Chemistry Chemical Physics. 21:12931-12947
DNA methyltransferases (DNMTs), responsible for the regulation of DNA methylation, have been regarded as promising drug targets for cancer therapy. However, high structural conservation of the catalytic domains of DNMTs poses a big challenge to desig
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::312b0718ddbde41824bb49a5ccdbd5d3
https://doi.org/10.1039/c9cp02024a
https://doi.org/10.1039/c9cp02024a
Publikováno v:
Drug discovery today. 24(12)
DNA methyltransferases (DNMTs) are a conserved family of cytosine methylases with crucial roles in epigenetic regulation. They have been considered as promising therapeutic targets for the epigenetic treatment of cancer. Therefore, DNMT inhibitors (D
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0ac1b37c501a11e16762fe216e67ba9a
https://pubmed.ncbi.nlm.nih.gov/31494187
https://pubmed.ncbi.nlm.nih.gov/31494187