Zobrazeno 1 - 10
of 19
pro vyhledávání: '"Tianlei, Sun"'
Autor:
Fanfan Xie, Wenjie Guo, Xingguo Wang, Kaixiang Zhou, Shanshan Guo, Yang Liu, Tianlei Sun, Shengjing Li, Zhiyang Xu, Qing Yuan, Huanqin Zhang, Xiwen Gu, Jinliang Xing, Shujuan Liu
Publikováno v:
Clinical and Translational Medicine, Vol 14, Iss 1, Pp n/a-n/a (2024)
Abstract Background Epithelial ovarian cancer (EOC) heavily relies on oxidative phosphorylation (OXPHOS) and exhibits distinct mitochondrial metabolic reprogramming. Up to now, the evolutionary pattern of somatic mitochondrial DNA (mtDNA) mutations i
Externí odkaz:
https://doaj.org/article/9c00821e9a6d405780258f0884d43413
Autor:
Wenting Li, Lingyun Wang, Tianlei Sun, Hao Tang, Brian Bui, Derong Cao, Ruibing Wang, Wei Chen
Publikováno v:
Communications Biology, Vol 4, Iss 1, Pp 1-11 (2021)
Li et al develop PPAB-PyS nanoparticles that simultaneously allows intracellular imaging and ratiometric detection of the intracellular polyamine. With an additional potential to consume polyamines via an irreversible chemical reaction, the authors t
Externí odkaz:
https://doaj.org/article/5474ef861536426291baad744c91fe77
Autor:
Lingyun Wang, Derong Cao, Wei Chen, Tianlei Sun, Ruibing Wang, Wenting Li, Brian Bui, Hao Tang
Publikováno v:
Communications Biology, Vol 4, Iss 1, Pp 1-11 (2021)
Communications Biology
Communications Biology
Polyamine detection and depletion have been extensively investigated for cancer prevention and treatment. However, the therapeutic efficacy is far from satisfactory, mainly due to a polyamine compensation mechanism from the systemic circulation in th
Publikováno v:
Nanoscale. 13:9570-9576
Glucose starvation has emerged as a therapeutic strategy to inhibit tumor growth by regulating glucose metabolism. However, the rapid proliferation of cancer cells could induce the hypoxic tumor microenvironment (TME) which limits the therapeutic eff
Amelioration of ulcerative colitis via inflammatory regulation by macrophage-biomimetic nanomedicine
Autor:
Cheng Gao, Jianwen Wei, Cheryl H. T. Kwong, Ludan Yue, Ruibing Wang, Jianxiang Zhang, Richard D. Ye, Tianlei Sun
Publikováno v:
Theranostics. 10:10106-10119
Ulcerative colitis (UC) is featured with relapsing inflammation in the colon, where macrophages are recruited and polarized locally into M1 type to drive further inflammation. Pharmacotherapy of UC has exhibited limited efficacy, mostly due to the po
Publikováno v:
ACS applied bio materials. 3(1)
Orally administered colon-targeted formulations of drugs are of great importance in managing diseases in the colon. However, it is often challenging to maintain the integrity of such formulations during delivery, particularly in the gastric environme
Publikováno v:
PLoS ONE, Vol 9, Iss 1, p e87221 (2014)
The medicinal plants of Huang-qi (Radix Astragali) and Sheng-ma (Cimicifuga foetida) demonstrate significantly better antioxidant effects when used in combination than when used alone. However, the bioactive components and interactional mechanism und
Externí odkaz:
https://doaj.org/article/78c9bf9a77754e79beaa6091953bcfa4
Publikováno v:
ACS Applied Materials & Interfaces. 11:3280-3289
Stretchable conductive polymer films are required to survive not only large tensile strain but also stay functional after the reduction in applied strain. In the deformation process, the elastomer substrate that is typically employed plays a critical
Publikováno v:
Organic Field-Effect Transistors XVII.
Viscoelastic polymer semiconductors have the potential to be effective components in stretchable electronics. These malleable materials provide a simple and effective approach to realize stretchable field effect transistors and sensors.[1] For succes
Publikováno v:
Journal of Power Sources. 297:442-448
A novel manganese dioxide (MnO 2 ) nanosheet network grown on nickel/polyvinylidene fluoride (Ni/PVDF) coaxial fiber membrane is successfully fabricated by a three-step route: the polyvinylidene fluoride fiber membrane is prepared by electrospinning