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pro vyhledávání: '"Tianjiong Yao"'
Autor:
Scott K. Silverman, Tianjiong Yao, Jack J. Przybyla, Benjamin M. Brandsen, Peter Yeh, Hannah J. Nilsson, Austin M. Woodard
Publikováno v:
Org Biomol Chem
DNAzymes were previously identified by in vitro selection for a variety of chemical reactions, including several biologically relevant peptide modifications. However, finding DNAzymes for peptide lysine acylation is a substantial challenge. By using
Autor:
Gregory C. Patton, Masha M. Rosenberg, Lizbeth Hedstrom, Alfred G. Redfield, Mary F. Roberts, Tianjiong Yao
Publikováno v:
Biochemistry
The remarkable power and specificity of enzyme catalysis rely on the dynamic alignment of the enzyme, substrates, and cofactors, yet the role of dynamics has usually been approached from the perspective of the protein. We have been using an underappr
Autor:
Tianjiong Yao, Jack Przybyla, Peter Yeh, Austin Woodard, Hannah Nilsson, Benjamin Brandsen, Scott Silverman
DNAzymes were previously identified by in vitro selection for a variety of chemical reactions, including several biologically relevant peptide modifications. However, finding DNAzymes for peptide lysine acylation is a substantial challenge. By using
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b26da0a351dd53870a947ba8123cee00
https://doi.org/10.26434/chemrxiv.13010318
https://doi.org/10.26434/chemrxiv.13010318
Publikováno v:
The FASEB Journal. 29
The overall reaction of guanosine monophosphate reductase (GMPR) converts GMP to IMP by using NADPH as a cofactor and it includes two sub-steps: (1) a deamination step that releases ammonia from GMP and forms the intermediate E-XMP*; (2) a hydride tr