Zobrazeno 1 - 10
of 355
pro vyhledávání: '"Tianhua Zhou"'
Autor:
Yongxia Chang, Hao Jin, Yun Cui, Feng Yang, Kanghua Chen, Wenjun Kuang, Chunxiao Huo, Zhangqi Xu, Ya Li, Aifu Lin, Bo Yang, Wei Liu, Shanshan Xie, Tianhua Zhou
Publikováno v:
Clinical and Translational Medicine, Vol 14, Iss 8, Pp n/a-n/a (2024)
Abstract Background RNA pseudouridylation is a critical post‐transcriptional modification that influences gene expression and impacts various biological functions. Despite its significance, the role of mRNA pseudouridylation in cancer remains poorl
Externí odkaz:
https://doaj.org/article/070c9d235c5b41bb853a21dbedd5e796
Autor:
Zhian Chen, Tianhua Zhou, Huan Luo, Zhen Wang, Qiang Wang, Rongmao Shi, Zian Li, Rongqing Pang, Hongbo Tan
Publikováno v:
Journal of Nanobiotechnology, Vol 22, Iss 1, Pp 1-20 (2024)
Abstract The current first-line treatment for repairing cartilage defects in clinical practice is the creation of microfractures (MF) to stimulate the release of mesenchymal stem cells (MSCs); however, this method has many limitations. Recent studies
Externí odkaz:
https://doaj.org/article/05aaf9f00a754d34b6ec5c36b83fae08
Publikováno v:
Journal of Orthopaedic Surgery and Research, Vol 18, Iss 1, Pp 1-12 (2023)
Abstract Background Osteochondral injury is a common sports injury, and hyaline cartilage does not regenerate spontaneously when injured. However, there is currently no gold standard for treating osteochondral defects. Osteochondral autograft transpl
Externí odkaz:
https://doaj.org/article/282f29fcb6c944acaffc8aa0236ff7b1
Autor:
Yipeng Zhang, Liying Wang, Zi-Dan Wang, Quan Zhou, Xuefei Zhou, Tianhua Zhou, Yi-Xin Guan, Xiangrui Liu
Publikováno v:
Journal of Nanobiotechnology, Vol 21, Iss 1, Pp 1-15 (2023)
Abstract Colon-targeted oral drug delivery systems (CDDSs) are desirable for the treatment of ulcerative colitis (UC), which is a disease with high relapse and remission rates associated with immune system inflammation and dysregulation localized wit
Externí odkaz:
https://doaj.org/article/6875cd13264e473c8c5395433e8e5006
Autor:
Shuang Li, Dongyang Guo, Qiang Sun, Lu Zhang, Yun Cui, Min Liu, Xixi Ma, Yiman Liu, Wenyu Cui, Leimin Sun, Lisong Teng, Liangjing Wang, Aifu Lin, Wei Liu, Wei Zhuo, Tianhua Zhou
Publikováno v:
Experimental and Molecular Medicine, Vol 55, Iss 2, Pp 457-469 (2023)
Gastric cancer: Gene shutdown helps spread to the liver Reduced activity of a key cell control gene mediates an interaction between gastric cancer cells and immune system cells called macrophages that allows the cancer to spread to the liver. Cancer
Externí odkaz:
https://doaj.org/article/83ff6f2437924bac978009348b9cfc0e
Publikováno v:
Acta Pharmaceutica Sinica B, Vol 13, Iss 1, Pp 327-343 (2023)
Extended circulation of anticancer nanodrugs in blood stream is essential for their clinical applications. However, administered nanoparticles are rapidly sequestered and cleared by cells of the mononuclear phagocyte system (MPS). In this study, we d
Externí odkaz:
https://doaj.org/article/08a0a8a3f3ac4c599cac15390909ad94
Autor:
Chengyu Shi, Ying Wang, Minjie Wu, Yu Chen, Fangzhou Liu, Zheyuan Shen, Yiran Wang, Shaofang Xie, Yingying Shen, Lingjie Sang, Zhen Zhang, Zerui Gao, Luojia Yang, Lei Qu, Zuozhen Yang, Xinyu He, Yu Guo, Chenghao Pan, Jinxin Che, Huaiqiang Ju, Jian Liu, Zhijian Cai, Qingfeng Yan, Luyang Yu, Liangjing Wang, Xiaowu Dong, Pinglong Xu, Jianzhong Shao, Yang Liu, Xu Li, Wenqi Wang, Ruhong Zhou, Tianhua Zhou, Aifu Lin
Publikováno v:
Nature Communications, Vol 13, Iss 1, Pp 1-18 (2022)
Cancer cells exploit immune checkpoint pathways, such as PD-1/PD-L1, to evade elimination by the immune system. Here, the authors demonstrate that TMUB1 regulates post-translational modifications of PD-L1 and that targeting the TMUB1/PD-L1 interactio
Externí odkaz:
https://doaj.org/article/5c9afa68434c4156b9404910dc8406e1
Autor:
Liang Chen, Yucong Wang, Jiamei Lin, Zhenxing Song, Qinwei Wang, Wenfang Zhao, Yan Wang, Xiaoyu Xiu, Yuqi Deng, Xiuzhi Li, Qiqi Li, Xiaolin Wang, Jingxin Li, Xu Liu, Kunpeng Liu, Jincong Zhou, Kuan Li, Yuchan Liu, Shanhui Liao, Qin Deng, Chao Xu, Qianwen Sun, Shengzhou Wu, Kaiming Zhang, Min-Xin Guan, Tianhua Zhou, Fei Sun, Xiujun Cai, Chuan Huang, Ge Shan
Publikováno v:
Nature Communications, Vol 13, Iss 1, Pp 1-18 (2022)
This study identifies the evolutionarily conserved Exportin 4 as an essential regulator in the nuclear export of circRNAs. Defective circRNA export results in R-loop formation and DNA damage in cells, as well as testis and neurological defects in mic
Externí odkaz:
https://doaj.org/article/bcca5f3009f14c1daba6d2c1908d957c
Autor:
Wenguang Tu, Yanqin Yang, Chunping Chen, Tianhua Zhou, Tianhao Li, Haojing Wang, Shuyang Wu, Yong Zhou, Dermot O’Hare, Zhigang Zou, Rong Xu
Publikováno v:
Small Structures, Vol 4, Iss 6, Pp n/a-n/a (2023)
Developing heterogeneous catalysts with identifiable catalytic sites provides opportunities to explore their structure–activity relationship. Covalent organic framework (COF) represents an emerging class of porous materials that have exhibited grea
Externí odkaz:
https://doaj.org/article/e21097108e7e41e09697db1898b5d6d7
Autor:
Wei Zhuo, Meng Sun, Kun Wang, Lu Zhang, Kai Li, Danyang Yi, Mengjie Li, Qiang Sun, Xixi Ma, Wei Liu, Lisong Teng, Chengqi Yi, Tianhua Zhou
Publikováno v:
Cell Discovery, Vol 8, Iss 1, Pp 1-17 (2022)
Abstract PCIF1 (phosphorylated CTD interacting factor 1) is the first reported RNA N6,2′-O-dimethyladenosine (m6Am) methyltransferase. However, the pathological significance of PCIF1 and m6Am modification remains unknown. Here we find that both PCI
Externí odkaz:
https://doaj.org/article/b54b203878e64d8fa6e37ceb682e4642