Zobrazeno 1 - 10
of 19
pro vyhledávání: '"Tianhua Lei"'
Autor:
Maribel Martinez, Wei Yu, Heather L. Menden, Tianhua Lei, Paula Monaghan-Nichols, Venkatesh Sampath
Publikováno v:
Frontiers in Pediatrics, Vol 11 (2023)
BackgroundNecrotizing enterocolitis (NEC) is a devastating disease in premature infants, and 50% of infants with surgical NEC develop neurodevelopmental defects. The mechanisms by which NEC-induced cytokine release and activation of inflammatory cell
Externí odkaz:
https://doaj.org/article/3ea3e78240fd4dc9968a1c57eebac9cc
Autor:
Yisong Qian, Ziwei Wang, Hongru Lin, Tianhua Lei, Zhou Zhou, Weilu Huang, Xuehan Wu, Li Zuo, Jie Wu, Yu Liu, Ling-Fang Wang, Xiao-Hui Guan, Ke-Yu Deng, Mingui Fu, Hong-Bo Xin
Publikováno v:
Signal Transduction and Targeted Therapy, Vol 7, Iss 1, Pp 1-12 (2022)
Abstract Endothelial activation plays an essential role in the pathogenesis of sepsis-induced acute lung injury, however, the detailed regulatory mechanisms remain largely unknown. Here, we reported that TRIM47, an E3 ubiquitin ligase of the triparti
Externí odkaz:
https://doaj.org/article/00d141d1317a485091f43f3ebbeaa8b3
Autor:
Martinez, Maribel, Wei Yu, Menden, Heather L., Tianhua Lei, Monaghan-Nichols, Paula, Sampath, Venkatesh
Publikováno v:
Frontiers in Pediatrics; 2023, p1-10, 10p
Autor:
Mingui Fu, Yisong Qian, Parth Patel, Paula Monaghan-Nichols, Chi H Lee, Tianhua Lei, Jianming Qiu, Hongbo Xin
Publikováno v:
Journal of Virology
bioRxiv
bioRxiv
Emerging evidence suggests that endothelial activation plays a central role in the pathogenesis of acute respiratory distress syndrome (ARDS) and multiorgan failure in patients with coronavirus disease 2019 (COVID-19). However, the molecular mechanis
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c1ad60dbffb5434946d912074fcd6a19
https://doi.org/10.1128/jvi.01396-21
https://doi.org/10.1128/jvi.01396-21
Autor:
Yisong Qian, Ziwei Wang, Hongru Lin, Tianhua Lei, Zhou Zhou, Weilu Huang, Xuehan Wu, Li Zuo, Jie Wu, Yu Liu, Ling-Fang Wang, Xiao-Hui Guan, Ke-Yu Deng, Mingui Fu, Hong-Bo Xin
Publikováno v:
Signal transduction and targeted therapy. 7(1)
Endothelial activation plays an essential role in the pathogenesis of sepsis-induced acute lung injury, however, the detailed regulatory mechanisms remain largely unknown. Here, we reported that TRIM47, an E3 ubiquitin ligase of the tripartite motif-
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2f74019975ec0e12a9fb416c5e813f5e
https://pubmed.ncbi.nlm.nih.gov/35513381
https://pubmed.ncbi.nlm.nih.gov/35513381
Autor:
Li Zuo, Ke-Yu Deng, Ling-Fang Wang, Zhou Zhou, Xiao-Hui Guan, Tianhua Lei, Xuehan Wu, Yu Liu, Hongru Lin, Weilu Huang, Hongbo Xin, Jie Wu, Mingui Fu, Yisong Qian, Ziwei Wang
Endothelial activation plays an essential role in the pathology of sepsis-induced acute lung injury, but the detailed regulatory mechanisms remain largely unknown. Here, we demonstrated that TRIM47, an ubiquitin E3 ligase of tripartite protein family
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::c5e9730d7e12ea2fa57ee74878b5b5b5
https://doi.org/10.1101/2021.09.15.460553
https://doi.org/10.1101/2021.09.15.460553
Autor:
Hongbo Xin, Fang Guo, Zhi-Sheng Jiang, Yong Li, Mingui Fu, Tianhua Lei, Paula Monaghan-Nichols, Shitao Li, Xuan Huang
Publikováno v:
Journal of Molecular Cell Biology
Although the adhesion molecules-mediated leukocyte adherence and infiltration into tissues is an important step of inflammation, the post-translational regulation of these proteins on the endothelial cells is poorly understood. Here, we report that T
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::78ab32744bb7d386aeaf90131226a5c3
http://europepmc.org/articles/PMC7181722
http://europepmc.org/articles/PMC7181722
Direct Activation of Endothelial Cells by SARS-CoV-2 Nucleocapsid Protein Is Blocked by Simvastatin.
Autor:
Yisong Qian1,2, Tianhua Lei1, Patel, Parth S.1, Lee, Chi H.3, Monaghan-Nichols, Paula1, Hong-Bo Xin2, Jianming Qiu4, Mingui Fu1 fum@umkc.edu
Publikováno v:
Journal of Virology. Dec2021, Vol. 95 Issue 23, p1-14. 14p.
Autor:
Anil Kumar, Yong Li, Fatma Saaoud, Tianhua Lei, Xiao-Qiang Yu, Christopher J. Papasian, Hui He, Xuan Huang, Daping Fan, Ari Melnick, Mingui Fu, Shengping Huang
Publikováno v:
Signal Transduction and Targeted Therapy
Although systemic inflammatory responses attributable to infection may lead to significant lung injury, the precise molecular mechanisms leading to lung damage are poorly understood and therapeutic options remain limited. Here, we show that myeloid m
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::29c2c8f3ebae56df7df2b78512fb5214
https://doi.org/10.1038/sigtrans.2017.66
https://doi.org/10.1038/sigtrans.2017.66
Autor:
Katherine F. Roby, Shaon Borosha, Tianhua Lei, Anamika Ratri, Wei Cui, Jay L. Vivian, Michael J. Soares, Kaiyu Kubota, Prabhakar Singh, Khursheed Iqbal, M.A. Karim Rumi, Damayanti Chakraborty, Michael W. Wolfe, Xiao Zhao, Pramod Dhakal
Publikováno v:
Endocrinology. 158(7)
Estrogens are essential hormones for the regulation of fertility. Cellular responses to estrogens are mediated by estrogen receptor α (ESR1) and estrogen receptor β (ESR2). In mouse and rat models, disruption of Esr1 causes infertility in both male
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9e23f9ed8bb59916054fb16c49dd9b59
https://pubmed.ncbi.nlm.nih.gov/28520870
https://pubmed.ncbi.nlm.nih.gov/28520870