Zobrazeno 1 - 10
of 131
pro vyhledávání: '"Tianhu Li"'
Publikováno v:
Biosensors, Vol 13, Iss 9, p 875 (2023)
DNA ligases are essential enzymes involved in DNA replication and repair processes in all organisms. These enzymes seal DNA breaks by catalyzing the formation of phosphodiester bonds between juxtaposed 5′ phosphate and 3′ hydroxyl termini in doub
Externí odkaz:
https://doaj.org/article/354f7f2a38dc45e99988fffa585bc666
Publikováno v:
Journal of Nanobiotechnology, Vol 19, Iss 1, Pp 1-14 (2021)
Abstract Most activity-based molecular probes are designed to target enzymes that catalyze the breaking of chemical bonds and the conversion of a unimolecular substrate into bimolecular products. However, DNA topoisomerases are a class of enzymes tha
Externí odkaz:
https://doaj.org/article/5b6187f821af420d8a499c8293faa5cf
Publikováno v:
Data in Brief, Vol 17, Iss , Pp 709-715 (2018)
The data presented in this article are related to the research article entitled ''Quantitative determination of linking number differences between circular polynucleosomes and histone H1-bound circular polynucleosomes'' Zhang et al. (in press) [1]. D
Externí odkaz:
https://doaj.org/article/c2815724e19345ef9ecf6671d617cc85
Publikováno v:
Bioinformatics
Motivation Drug repositioning is an attractive alternative to de novo drug discovery due to reduced time and costs to bring drugs to market. Computational repositioning methods, particularly non-black-box methods that can account for and predict a dr
Publikováno v:
Nano Letters. 21:1384-1391
We report here a novel class of cation transporters with extreme simplicity, opening a whole new dimension of scientific research for finding small molecule-based cation transporters for therapeutic applications. Comprising three modular components (
Autor:
Ruijuan Ye, Feng Chen, Tianxiang Wang, Hao Zhang, Jie Shen, Huaqiang Zeng, Ning Li, Tianhu Li, Teck-Peng Loh, Yi Yan Yang
Publikováno v:
Journal of the American Chemical Society. 142:21082-21090
Searching for membrane-active synthetic analogues that are structurally simple yet functionally comparable to natural channel proteins has been of central research interest in the past four decades, yet custom design of the ion transport selectivity
Autor:
Tianhu, Li, sha,Luoguangyi, Yang
Publikováno v:
In Energy Procedia 2012 16 Part A:477-482
Publikováno v:
Chemical Communications. 56:1211-1214
A minor alteration in structure of a previously reported synthetic K+ channel via replacing the electron-withdrawing group with an electron-donating group leads to enhancement in activity by 160% and in selectivity by >50%. As a result, the new K+ ch
Publikováno v:
Nano letters. 21(3)
We report here a novel class of cation transporters with extreme simplicity, opening a whole new dimension of scientific research for finding small molecule-based cation transporters for therapeutic applications. Comprising three modular components (
Autor:
Ning, Li, Feng, Chen, Jie, Shen, Hao, Zhang, Tianxiang, Wang, Ruijuan, Ye, Tianhu, Li, Teck Peng, Loh, Yi Yan, Yang, Huaqiang, Zeng
Publikováno v:
Journal of the American Chemical Society. 142(50)
Searching for membrane-active synthetic analogues that are structurally simple yet functionally comparable to natural channel proteins has been of central research interest in the past four decades, yet custom design of the ion transport selectivity