Zobrazeno 1 - 10
of 14
pro vyhledávání: '"Tianhe Xiao"'
Autor:
Xiao Niu, Zhiqiang Li, Jing Wang, Fanchong Jian, Yuanling Yu, Weiliang Song, Ayijiang Yisimayi, Shuo Du, Zhiying Zhang, Qianran Wang, Ran An, Yao Wang, Peng Wang, Haiyan Sun, Lingling Yu, Sijie Yang, Tianhe Xiao, Qingqing Gu, Fei Shao, Youchun Wang, Junyu Xiao, Yunlong Cao
Publikováno v:
Emerging Microbes and Infections, Vol 13, Iss 1 (2024)
A multitude of functional mutations continue to emerge on the N-terminal domain (NTD) of the spike protein in SARS-CoV-2 Omicron subvariants. Understanding the immunogenicity of Omicron NTD and the properties of antibodies elicited by it is crucial f
Externí odkaz:
https://doaj.org/article/8e6927d6bbab41f59fa63f324f3ab0ce
Autor:
Changzhi Zhao, Hailong Liu, Tianhe Xiao, Zichang Wang, Xiongwei Nie, Xinyun Li, Ping Qian, Liuxing Qin, Xiaosong Han, Jinfu Zhang, Jinxue Ruan, Mengjin Zhu, Yi-Liang Miao, Bo Zuo, Kui Yang, Shengsong Xie, Shuhong Zhao
Publikováno v:
Nature Communications, Vol 11, Iss 1, Pp 1-15 (2020)
Here the authors report the construction of a genome-scale porcine CRISPR/Cas9 library, called PigGeCKO, for screening and analyses of host resistance genes and factors associated with Japanese encephalitis virus replication.
Externí odkaz:
https://doaj.org/article/c8d5432caf5247bdb69440141b17ee99
Autor:
Ayijiang Yisimayi, Weiliang Song, jing wang, Fanchong Jian, Yuanling Yu, Xiaosu Chen, Yanli Xu, Sijie Yang, Xiao Niu, Tianhe Xiao, Jing Wang, Ran An, Na Zhang, Yao Wang, Peng Wang, Lijuan Zhao, Haiyan Sun, Lingling Yu, Qingqing Gu, Fei Shao, Ronghua Jin, Zhongyang Shen, Xiaoliang Xie, Youchun Wang, Yunlong Cao
The continuous emergence of highly immune evasive SARS-CoV-2 variants, like XBB.1.51,2and XBB.1.163,4, highlights the need to update COVID-19 vaccine compositions. However, immune imprinting induced by wildtype (WT)-based vaccination would compromise
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::bce3152bb2b65b6ea778e9c63f430625
https://doi.org/10.21203/rs.3.rs-2887287/v1
https://doi.org/10.21203/rs.3.rs-2887287/v1
Autor:
Yunlong Cao, Fanchong Jian, Zhiying Zhang, Ayijiang Yisimayi, Xiaohua Hao, Linlin Bao, Fei Yuan, Yuanling Yu, Shuo Du, Jing Wang, Tianhe Xiao, Weiliang Song, Ying Zhang, Pulan Liu, Ran An, Peng Wang, Yao Wang, Sijie Yang, Xiao Niu, Yuhang Zhang, Qingqing Gu, Fei Shao, Yaling Hu, Weidong Yin, Aihua Zheng, Youchun Wang, Chuan Qin, Ronghua Jin, Junyu Xiao, Xiaoliang Sunney Xie
Publikováno v:
Cell reports. 41(12)
SARS-CoV-2 Omicron sublineages have escaped most RBD-targeting therapeutic neutralizing antibodies (NAbs), which proves the previous NAb drug screening strategies deficient against the fast-evolving SARS-CoV-2. Better broad NAb drug candidate selecti
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ca4a276ea9bd797d9ba121c69b06c0c2
https://pubmed.ncbi.nlm.nih.gov/36493787
https://pubmed.ncbi.nlm.nih.gov/36493787
Autor:
Yunlong Cao, Fanchong Jian, Jing Wang, Yuanling Yu, Weiliang Song, Ayijiang Yisimayi, Ran An, Xiaosu Chen, Na Zhang, Yao Wang, Peng Wang, Lijuan Zhao, Haiyan Sun, Lingling Yu, Sijie Yang, Xiao Niu, Tianhe Xiao, Qingqing Gu, Fei Shao, Xiaohua Hao, Yanli Xu, Ronghua Jin, Zhongyang Shen, Youchun Wang, Xiaoliang Sunney Xie
Continuous evolution of Omicron has led to a rapid and simultaneous emergence of numerous variants that display growth advantages over BA. 5. Despite their divergent evolutionary courses, mutations on their receptor-binding domain (RBD) converge on s
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::22867875784c4423d4c7b6f34dc25b4b
https://doi.org/10.1101/2022.09.15.507787
https://doi.org/10.1101/2022.09.15.507787
Autor:
Yunlong Cao, Weiliang Song, Lei Wang, Pan Liu, Can Yue, Fanchong Jian, Yuanling Yu, Ayijiang Yisimayi, Peng Wang, Yao Wang, Qianhui Zhu, Jie Deng, Wangjun Fu, Lingling Yu, Na Zhang, Jing Wang, Tianhe Xiao, Ran An, Lu Liu, Sijie Yang, Xiao Niu, Qingqing Gu, Fei Shao, Xiaohua Hao, Ronghua Jin, Youchun Wang, Xiaoliang Sunney Xie, Xiangxi Wang
Recently emerged SARS-CoV-2 Omicron subvariant, BA.2.75, displayed a local growth advantage over BA.2.38, BA.2.76 and BA.5 in India. The underlying mechanism of BA.2.75’s enhanced infectivity, especially compared to BA.5, remains unclear. Here, we
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::755530382ac16801f12224fa3e076522
https://doi.org/10.1101/2022.07.18.500332
https://doi.org/10.1101/2022.07.18.500332
Autor:
Yongzheng Li, Jiajing Wu, Xiaoyu Xu, Ran An, Xiaoliang Sunney Xie, Rui Shi, Na-Na Zhang, Chuanping Gao, Liyang Song, Yingmin Ma, Ayijiang Yisimayi, Xuemei Li, Yali Bai, Y Cao, Youchun Wang, Tianhe Xiao, Shuo Du, Yangyang Wei, Yifei Zhang, Wenping Ma, Xiang Li, Junyu Xiao, Weiliang Song, Cheng-Feng Qin, Bin Su, Shuo Liu, Jing Wang, Zhiying Zhang, Xiaofeng Li, Tianjiao Yuan, Ronghua Jin, Yingmei Feng, Yang Dou, Yonghong Zhang, Bai Lu, Weijin Huang, Xianghua Guo
Publikováno v:
Cell Research
SARS-CoV-2 variants could induce immune escape by mutations on the receptor-binding domain (RBD) and N-terminal domain (NTD). Here we report the humoral immune response to circulating SARS-CoV-2 variants, such as 501Y.V2 (B.1.351), of the plasma and
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0cc6da328c967b8d310b738c681960ad
https://doi.org/10.1038/s41422-021-00514-9
https://doi.org/10.1038/s41422-021-00514-9
Autor:
Yunlong Cao, Ayijiang Yisimayi, Fanchong Jian, Weiliang Song, Tianhe Xiao, Lei Wang, Shuo Du, Jing Wang, Qianqian Li, Xiaosu Chen, Yuanling Yu, Peng Wang, Zhiying Zhang, Pulan Liu, Ran An, Xiaohua Hao, Yao Wang, Rui Feng, Haiyan Sun, Lijuan Zhao, Wen Zhang, Dong Zhao, Jiang Zheng, Lingling Yu, Can Li, Na Zhang, Rui Wang, Xiao Niu, Sijie Yang, Xuetao Song, Yangyang Chai, Ye Hu, Yansong Shi, Linlin Zheng, Zhiqiang Li, Qingqing Gu, Fei Shao, Weijin Huang, Ronghua Jin, Zhongyang Shen, Youchun Wang, Xiangxi Wang, Junyu Xiao, Xiaoliang Sunney Xie
Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) Omicron sublineages BA.2.12.1, BA.4 and BA.5 exhibit higher transmissibility than the BA.2 lineage1. The receptor binding and immune-evasion capability of these recently emerged variants re
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c04bbe2b8fb766303ceed11223674f1c
https://doi.org/10.1101/2022.04.30.489997
https://doi.org/10.1101/2022.04.30.489997
Autor:
Xiaoliang Xie, Yunlong Cao, Ayijiang Yisimayi, Fanchong Jian, Weiliang Song, Tianhe Xiao, Lei Wang, Shuo Du, jing wang, Qianqian Li, Xiaosu Chen, Peng Wang, Zhiying Zhang, Pulan Liu, Ran An, Xiaohua Hao, Yao Wang, Jing Wang, Rui Feng, Haiyan Sun, Lijuan Zhao, Wen Zhang, Dong Zhao, Jiang Zheng, Lingling Yu, Can Li, Na Zhang, Rui Wang, Xiao Niu, Sijie Yang, Xuetao Song, Linlin Zheng, Zhiqiang Li, Qingqing Gu, Fei Shao, Weijin Huang, Jin ronghua, Zhongyang Shen, Youchun Wang, Xiangxi Wang, Junyu Xiao
Recent emergence of SARS-CoV-2 Omicron sublineages BA.2.12.1, BA.2.13, BA.4 and BA.5 all contain L452 mutations and show potential higher transmissibility over BA.2. The new variants’ receptor binding and immune evasion capability require immediate
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::af9296cbef9bc8386a0a59512dfa9800
https://doi.org/10.21203/rs.3.rs-1611421/v1
https://doi.org/10.21203/rs.3.rs-1611421/v1
Autor:
Yunlong Cao, Ayijiang Yisimayi, Fanchong Jian, Tianhe Xiao, Weiliang Song, Jing Wang, Shuo Du, Zhiying Zhang, Pulan Liu, Xiaohua Hao, Qianqian Li, Xiaosu Chen, Lei Wang, Peng Wang, Ran An, Yao Wang, Peng Yang, Haiyan Sun, Lijuan Zhao, Wen Zhang, Dong Zhao, Jiang Zheng, Lingling Yu, Can Li, Na Zhang, Rui Wang, Xiao Niu, Sijie Yang, Xuetao Song, Linlin Zheng, Zhiqiang Li, Qingqing Gu, Fei Shao, Weijin Huang, Youchun Wang, Zhongyang Shen, Xiangxi Wang, Ronghua Jin, Junyu Xiao, Xiaoliang Sunney Xie
Omicron sub-lineage BA.2 has rapidly surged globally, accounting for over 60% of recent SARS-CoV-2 infections. Newly acquired RBD mutations and high transmission advantage over BA.1 urge the investigation of BA.2’s immune evasion capability. Here,
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::7d2266f9cac71da58b5e22b9cf3c0cc6
https://doi.org/10.1101/2022.02.07.479349
https://doi.org/10.1101/2022.02.07.479349