Zobrazeno 1 - 10
of 47
pro vyhledávání: '"Tianhai Ji"'
Publikováno v:
Cell Death and Disease, Vol 15, Iss 3, Pp 1-10 (2024)
Abstract Recently, crystallographic studies have demonstrated that BMS-202, a small-molecule compound characterized by a methoxy-1-pyridine chemical structure, exhibits a high affinity to PD-L1 dimerization. However, its roles and mechanisms in gliob
Externí odkaz:
https://doaj.org/article/06502d0c243748e19c45710e9b4148a9
Autor:
Yu An, Jinchao Zhu, Qihui Xie, Jianzhou Feng, Yanli Gong, Qian Fan, Jiao Cao, Zhi Huang, Weixiong Shi, Qingyuan Lin, Lingling Wu, Chaoyong Yang, Tianhai Ji
Publikováno v:
Advanced Science, Vol 11, Iss 20, Pp n/a-n/a (2024)
Abstract To evade immune surveillance, tumor cells express ectonucleotide pyrophosphatase phosphodiesterase 1 (ENPP1) on the surface of their membrane, which degrades extracellular cyclic GMP‐AMP (cGAMP), thereby inhibiting the cyclic GMP‐AMP syn
Externí odkaz:
https://doaj.org/article/5eb262401ddb40739bc313b105a7ca39
Publikováno v:
Frontiers in Oncology, Vol 12 (2022)
BackgroundGlioma is an incurable malignant lesion with poor outcome characterized by easy recurrence after surgery with or without radiotherapy and chemotherapy. Studies have shown that COL6A2 is closely related to the tumorigenesis and development o
Externí odkaz:
https://doaj.org/article/5b2a64efb0f7448d9fe7e8426574fb2d
Publikováno v:
Frontiers in Oncology, Vol 12 (2022)
Penoscrotum extramammary Paget disease (pEMPD) is a rare cutaneous carcinoma with an unknown cell origin. pEMPD always presents as a tumor in situ with an indolent process, whereas some progress into invasive forms with more aggressive behavior. The
Externí odkaz:
https://doaj.org/article/72f4a9e36020412e91f44dd6b5b5725f
Autor:
Guopeng Yu, Bo Liang, Keneng Yin, Ming Zhan, Xin Gu, Jiangyi Wang, Shangqing Song, Yushan Liu, Qing Yang, Tianhai Ji, Bin Xu
Publikováno v:
Frontiers in Oncology, Vol 12 (2022)
Prostate cancer is still the main male health problem in the world. The role of metabolism in the occurrence and development of prostate cancer is becoming more and more obvious, but it is not clear. Here we firstly identified a metabolism-related ge
Externí odkaz:
https://doaj.org/article/988368ff56bb43c6ac2853f8f112ed96
Publikováno v:
Frontiers in Medicine, Vol 8 (2022)
BackgroundCoronavirus disease 2019 (COVID-19) pandemic continues to spread across the world. Specimens of blood, body fluids and excreta received in the department of pathology undoubtedly increased the risk of infection, especially in some hospitals
Externí odkaz:
https://doaj.org/article/25f5937be7014edb9f689bec02868722
Autor:
Kun Liu, Qing Zhang, Haitao Lan, Liping Wang, Pengfei Mou, Wei Shao, Dan Liu, Wensheng Yang, Zhen Lin, Qingyuan Lin, Tianhai Ji
Publikováno v:
International Journal of Molecular Sciences, Vol 16, Iss 9, Pp 21897-21910 (2015)
The general control of nucleotide synthesis 5 (GCN5), which is one kind of lysine acetyltransferases, regulates a number of cellular processes, such as cell proliferation, differentiation, cell cycle and DNA damage repair. However, its biological rol
Externí odkaz:
https://doaj.org/article/31e7347666ea444d9a5a7b3fbfbf9a25
Publikováno v:
Talanta. 235
An end-modified 2′-O-methyl molecular beacon (eMB) with unique nuclease resistance was designed and prepared. The eMB can resist the enzymatic digestion by DNase I, which would otherwise occur upon the hybridization of the eMB with a complementary
Publikováno v:
Applied Immunohistochemistry & Molecular Morphology. 26:e93-e100
Many tumors, especially gliomas, contain an isocitrate dehydrogenase (IDH) mutation that can be used for clinical diagnosis and prognosis. Our study aimed to develop a new reliable detection assay for IDH1 and IDH2 mutations for clinical diagnosis ba