Zobrazeno 1 - 10
of 149
pro vyhledávání: '"Tian-ci Yang"'
Autor:
Wei Li, Xi Luo, Xin-Qi Zheng, Qiu-Ling Li, Ze Li, Qing-Qi Meng, Yan-Li Zeng, Yu Lin, Tian-Ci Yang
Publikováno v:
Emerging Microbes and Infections, Vol 13, Iss 1 (2024)
The incompletely eliminated Treponema pallidum (T. pallidum) during primary syphilis chancre infection can result in the progression of secondary, tertiary, or latent syphilis in individuals, suggesting that T. pallidum has successfully evaded the im
Externí odkaz:
https://doaj.org/article/b56c22d471b84f879c2bd278613eb663
Autor:
Qiu-Yan Xu, Xin-Qi Zheng, Wei-Ming Ye, Dong-Yu Yi, Ze Li, Qing-Qi Meng, Man-Li Tong, Dan Liu, Tian-Ci Yang
Publikováno v:
Virulence, Vol 15, Iss 1 (2024)
ABSTRACTThe evasive tactics of Treponema pallidum pose a major challenge in combating and eradicating syphilis. Natural killer (NK) cells mediate important effector functions in the control of pathogenic infection, preferentially eliminating targets
Externí odkaz:
https://doaj.org/article/3912b4cc1d2942aa8d6314d367350f51
Publikováno v:
npj Vaccines, Vol 8, Iss 1, Pp 1-10 (2023)
Abstract Syphilis has resurged in many countries, which has called attention to vaccine development. Based on the immunization-based rabbit model of infection with the Nichols strain, this study explored the protective immune response of a controvers
Externí odkaz:
https://doaj.org/article/4d7117f3421d4be3bf7ea3c0a3b2659a
Publikováno v:
Biomedicine & Pharmacotherapy, Vol 167, Iss , Pp 115628- (2023)
The systemic immune response, including B- and T-cell reactions, plays a corresponding role in syphilis infections. The TP0136 protein is a target of the immune response in infected hosts and may mediate the immune response. Here, we developed a meth
Externí odkaz:
https://doaj.org/article/0daae3c7bac143fc99c8e4ac1246dcd1
Publikováno v:
International Journal of Infectious Diseases, Vol 127, Iss , Pp 36-44 (2023)
ABSTRACT: Objectives: To evaluate the possibility of using cerebrospinal fluid (CSF) ubiquitin C-terminal hydrolase L1 (UCH-L1), glial fibrillary acidic protein (GFAP), and neurofilament light protein (NF-L) for the diagnosis of neurosyphilis (NS). M
Externí odkaz:
https://doaj.org/article/da62c76091b6486394a0f745ae2599ed
Publikováno v:
Microbiology Spectrum, Vol 11, Iss 4 (2023)
ABSTRACT Heterogeneous tprK sequences have been hypothesized to be an important factor for persistent infection of Treponema pallidum subsp. pallidum (T. pallidum) in humans. Previous research has only explored tprK diversity using a rabbit model inf
Externí odkaz:
https://doaj.org/article/684d5de1c7ee4e148472f9226be6780f
Autor:
Huachun Zou, Zhen Lu, Wenjia Weng, Ligang Yang, Luoyao Yang, Xinying Leng, Junfeng Wang, Yi-Fan Lin, Jiaxin Wu, Leiwen Fu, Xiaohui Zhang, Yuwei Li, Liuyuan Wang, Xinsheng Wu, Xinyi Zhou, Tian Tian, Lixia Huang, Christina M. Marra, Bin Yang, Tian-Ci Yang, Wujian Ke
Publikováno v:
EClinicalMedicine, Vol 62, Iss , Pp 102080- (2023)
Summary: Background: The ability to accurately identify the absolute risk of neurosyphilis diagnosis for patients with syphilis would allow preventative and therapeutic interventions to be delivered to patients at high-risk, sparing patients at low-r
Externí odkaz:
https://doaj.org/article/3d66e18afc7c4d3c9fff785eb321b583
Publikováno v:
Microbiology Spectrum, Vol 11, Iss 3 (2023)
ABSTRACT TprK antigenic variation is acknowledged as an important strategy developed by Treponema pallidum to achieve immune evasion. Previous studies applied short-read sequencing to explore tprK gene sequence diversity in clinical samples; however,
Externí odkaz:
https://doaj.org/article/0c53a73caf2647a7b3a154a69a3805e4
Publikováno v:
Heliyon, Vol 9, Iss 6, Pp e17157- (2023)
Background: The cerebrospinal fluid (CSF) venereal disease research laboratory (VDRL) test remains the standard for the laboratory diagnosis of neurosyphilis. The toluidine red unheated serum test (TRUST) is an alternative to the VDRL test as a serol
Externí odkaz:
https://doaj.org/article/a9a3366540044ce1b1df1a5c1a3ec914
Publikováno v:
Journal of Infection and Public Health, Vol 15, Iss 12, Pp 1494-1496 (2022)
To evaluate the application of cycle threshold (Ct) values of coronavirus disease 2019 (COVID-19) patients in predicting epidemic dynamics and monitoring surface contamination. The Ct value of reverse transcriptase-polymerase chain reaction for SARS
Externí odkaz:
https://doaj.org/article/f7702e98dec047df8659a5ee4f8a4d7a