Zobrazeno 1 - 10 of 22 pro vyhledávání: '"Tian-Yu Cai"'
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Data from Synergistic Antitumor Activity of Gemcitabine and ABT-737 In Vitro and In Vivo through Disrupting the Interaction of USP9X and Mcl-1
Autor: Bo Yang, Qiao-jun He, Neng-ming Lin, Yong-zhou Hu, Xiao-wu Dong, Hai Jiang, Liu-qing Yang, Hong Zhu, Tian-yu Cai, Chong Zhang
The Bcl-2 antagonist ABT-737 targets Bcl-2/Bcl-xL, but not Mcl-1, which may confer resistance to this agent in various cancers with high levels of Mcl-1. Here, we showed that the combination of gemcitabine and ABT-737 exhibited synergistic cytotoxici
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::dc21bba522acfd16e1d4d2120bb3ad8b
https://doi.org/10.1158/1535-7163.c.6535453
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3
Supplementary Table 1 - 2 from Tirapazamine Sensitizes Hepatocellular Carcinoma Cells to Topoisomerase I Inhibitors via Cooperative Modulation of Hypoxia-Inducible Factor-1α
Autor: Bo Yang, Qiao-Jun He, Jian-Shu Lou, Ling Ding, Jun Zhang, Ji Cao, Hong Zhu, Xiao-Wen Liu, Tian-Yu Cai
PDF file - 135K, Supplementary Table S1. CI Values of SN-38 at Concentrations Applied in Combination with Tirapazamine in Different Liver Cell Lines; Supplementary Table S2. In Vivo Efficacy of CPT-11 in Combination with Tirapazamine; and supplementa
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::57c338e356a43e5fccadf7593aabcfd1
https://doi.org/10.1158/1535-7163.22500610
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7
Data from Tirapazamine Sensitizes Hepatocellular Carcinoma Cells to Topoisomerase I Inhibitors via Cooperative Modulation of Hypoxia-Inducible Factor-1α
Autor: Bo Yang, Qiao-Jun He, Jian-Shu Lou, Ling Ding, Jun Zhang, Ji Cao, Hong Zhu, Xiao-Wen Liu, Tian-Yu Cai
Topoisomerase I inhibitors are a class of anticancer drugs with a broad spectrum of clinical activity. However, they have limited efficacy in hepatocellular cancer. Here, we present in vitro and in vivo evidence that the extremely high level of hypox
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::096522284f042fe26aff132c2d4f393e
https://doi.org/10.1158/1535-7163.c.6536518.v1
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