Zobrazeno 1 - 8
of 8
pro vyhledávání: '"Tian-Kui Ma"'
Autor:
Xin Li, Tian-Kui Ma, Pu Wang, Hang Shi, Sang Hai, Yu Qin, Yun Zou, Wan-Ting Zhu, Hui-Min Li, Yan-Nong Li, Li Yin, Yan-Yan Xu, Qi Yang, Shuang Zhang, Hong Ding
Publikováno v:
Cell Death and Disease, Vol 15, Iss 6, Pp 1-14 (2024)
Abstract In chronic kidney disease (CKD), renal fibrosis is an unavoidable result of various manifestations. However, its pathogenesis is not yet fully understood. Here, we revealed the novel role of Homeobox D10 (HOXD10) in CKD-related fibrosis. HOX
Externí odkaz:
https://doaj.org/article/619153bcdf744036ad2a12ae00d8ca0c
Autor:
Xin Li, Qiu-Ling Fan, Tian-Kui Ma, Cong Liu, Hang Shi, Yuan-Yuan Sun, Yue Wang, Dong-Xue Ding, Ao Tang, Yu Qin, Qi Yang, Hong Ding, Hang-Yu Li, Wei-Neng Fu
Publikováno v:
iScience, Vol 26, Iss 9, Pp 107609- (2023)
Summary: Tubulointerstitial abnormalities contribute to the progression of diabetic kidney disease (DKD). However, the underlying mechanism of the pathobiology of tubulointerstitial disease is largely unknown. Here, we showed that MYCT1 expression wa
Externí odkaz:
https://doaj.org/article/fa9384a2c35a495994959e43f03b31ad
Autor:
Xin Li, Tian-Kui Ma, Min Wang, Xiao-Dan Zhang, Tian-Yan Liu, Yue Liu, Zhao-Hui Huang, Yong-Hong Zhu, Shuang Zhang, Li Yin, Yan-Yan Xu, Hong Ding, Cong Liu, Hang Shi, Qiu-Ling Fan
Publikováno v:
Frontiers in Pharmacology, Vol 14 (2023)
Objectives: Dimeric pyruvate kinase (PK) M2 (PKM2) plays an important role in promoting the accumulation of hypoxia-inducible factor (HIF)-1α, mediating aberrant glycolysis and inducing fibrosis in diabetic kidney disease (DKD). The aim of this work
Externí odkaz:
https://doaj.org/article/fd04f1bf6d07421e801e3eed6d7c477a
Autor:
Min Wang, Xin Li, Hang Mei, Zhao-Hui Huang, Yue Liu, Yong-Hong Zhu, Tian-Kui Ma, Qiu-Ling Fan
Publikováno v:
Frontiers in Genetics, Vol 13 (2022)
The aim of this study is to apply a Mendelian randomization (MR) design to investigate the potential causal associations between the body mass index (BMI), body fat mass such as trunk fat mass and waist circumference (WC), and diabetic kidney disease
Externí odkaz:
https://doaj.org/article/b38fc0cd304348369805c70980409779
Autor:
Si Wen, Cong Xiao Zhang, Xin Li, Tian Kui Ma, Lu Lu Li, Qiu Ling Fan, Li Xu, Xin Wang Zhu, Xu Wang, Nan Liu
Publikováno v:
Journal of Cellular and Molecular Medicine
The persistent transactivation of epidermal growth factor receptor (EGFR) causes subsequent activation of the TGF‐β/Smad3 pathway, which is closely associated with fibrosis and cell proliferation in diabetic nephropathy (DN), but the exact mechani
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::aa71a7c5043b56b5e91dbcbf1d56f95c
http://europepmc.org/articles/PMC7701572
http://europepmc.org/articles/PMC7701572
Publikováno v:
Diabetes, Metabolic Syndrome and Obesity: Targets and Therapy. 12:2597-2608
Purpose This study aimed to investigate whether ursolic acid (UA) mitigates renal inflammation, oxidative stress and fibrosis by regulating the angiotensin II type 1 receptor-associated protein (ARAP1)/angiotensin II type 1 receptor (AT1R) signaling
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::5be4dfaa6aefb1f67e2d28ef5b8d5615
https://doi.org/10.2147/dmso.s222323
https://doi.org/10.2147/dmso.s222323
Publikováno v:
Diabetes, Metabolic Syndrome and Obesity: Targets and Therapy. 12:1297-1309
Background Diabetic nephropathy (DN) is a lethal diabetic microvascular complication characterized by chronic low-grade inflammation. The NOD-like receptor pyrin domain-containing protein 3 (NLRP3) inflammasome is implicated in the progression of DN.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::c61cb09bcf2dfe842edd491ec45cdef4
https://doi.org/10.2147/dmso.s199802
https://doi.org/10.2147/dmso.s199802
Publikováno v:
Diabetes, Metabolic Syndrome and Obesity: Targets and Therapy
Purpose This study aimed to investigate whether ursolic acid (UA) mitigates renal inflammation, oxidative stress and fibrosis by regulating the angiotensin II type 1 receptor-associated protein (ARAP1)/angiotensin II type 1 receptor (AT1R) signaling
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::a9d20ae51dba566e0780ef6b6cb245cc
https://pubmed.ncbi.nlm.nih.gov/31849504
https://pubmed.ncbi.nlm.nih.gov/31849504