Zobrazeno 1 - 10
of 19
pro vyhledávání: '"Tian-Fang Jiang"'
Publikováno v:
Brazilian Journal of Medical and Biological Research, Vol 54, Iss 10 (2021)
The etiology of subacute combined degeneration (SCD) of the spinal cord is closely associated with vitamin B12 (VitB12) deficiency. The clinical manifestations of SCD are complex and vary substantially. Due to some SCD patients with atypical manifest
Externí odkaz:
https://doaj.org/article/e82781dc4d024be4b020c4f7cae2079c
Autor:
Chao Gao, Mei-Yu Quan, Qian-Jie Chen, Ruo Yang, Yuanyuan Wu, Jia-Yu Liu, Zhong-Yuan Lin, Xue Li, Jue-Ting Cai, Tian-Fang Jiang, Le Xu, Majid Mossahebi-Mohammadi, Qiang Guo, Jin-San Zhang
Publikováno v:
Frontiers in Oncology, Vol 11 (2021)
Pancreatic ductal adenocarcinoma (PDAC) is the most aggressive human malignancy and intrinsically resistant to conventional therapies. YAP1, as a key downstream effector of the Hippo pathway, plays an important role in tumorigenesis including PDAC. A
Externí odkaz:
https://doaj.org/article/761e36c1fb9f4f36b417c17589c29bf0
Autor:
Chuan-Ying Xu, Wen-Yan Kang, Yi-Meng Chen, Tian-Fang Jiang, Jia Zhang, Li-Na Zhang, Jian-Qing Ding, Jun Liu, Sheng-Di Chen
Publikováno v:
Frontiers in Aging Neuroscience, Vol 9 (2017)
α-Synuclein misfolding and aggregation play an important role in the pathogenesis of Parkinson’s disease (PD). Loss of function and mutation of the PARK7/DJ-1 gene cause early-onset familial PD. DJ-1 can inhibit α-synuclein aggregation, and may f
Externí odkaz:
https://doaj.org/article/db2f3e9fccec49a886b20403b9ef7acd
Autor:
Sheng-di CHEN, Tian-fang JIANG
Publikováno v:
Chinese Journal of Contemporary Neurology and Neurosurgery, Vol 13, Iss 7, Pp 551-554 (2013)
Externí odkaz:
https://doaj.org/article/19308a6e55394a6d827677bc727e545a
Autor:
Qiang Guo, Mei‐Yu Quan, Le Xu, Yaxin Cai, Jue‐Ting Cai, Xue Li, Guifeng Feng, Aiping Chen, Weiwei Yang, Qhaweni Dhlamini, Tian‐Fang Jiang, Chengguo Shen, Chengshui Chen, Jin‐San Zhang
Publikováno v:
Journal of cellular and molecular medicine. 26(4)
YAP1, a key mediator of the Hippo pathway, plays an important role in tumorigenesis. Alternative splicing of human YAP1 mRNA results in two major isoforms: YAP1-1, which contains a single WW domain, and YAP1-2, which contains two WW domains, respecti
Autor:
Jianqing Ding, Jake G. Hoekstra, Jing Zhang, Sheng-Di Chen, Xin Heng, Wenyan Kang, Jun Liu, Tian-Fang Jiang
Publikováno v:
Neurobiology of Aging. 36:2304-2318
Activated microglia are commonly observed in individuals with neurodegenerative disorders, including Parkinson's disease (PD) and are believed to contribute to neuronal death. This process occurs at least due partially to nicotinamide adenine dinucle
Autor:
Sheng-Di Chen, Yi-Meng Chen, Chuan-Ying Xu, Tian-Fang Jiang, Jun Liu, Jianqing Ding, Wenyan Kang, Lina Zhang, Jia Zhang
Publikováno v:
Frontiers in Aging Neuroscience
Frontiers in Aging Neuroscience, Vol 9 (2017)
Frontiers in Aging Neuroscience, Vol 9 (2017)
α-Synuclein misfolding and aggregation play an important role in the pathogenesis of Parkinson’s disease (PD). Loss of function and mutation of the PARK7/DJ-1 gene cause early-onset familial PD. DJ-1 can inhibit α-synuclein aggregation, and may f
Publikováno v:
Aging and Disease
Background Parkinson's disease (PD) patients with 10 years or more survival (PD-10) are not well characterized. The aim of this study was to evaluate the main issues facing PD-10 patients and identify factors that independently contributed to quality
Autor:
Ying Wang, Qin Xiao, Jun Liu, Qian Sun, Tian Wang, Pei Huang, Dunhui Li, Sheng-Di Chen, Tian-Fang Jiang
Publikováno v:
Aging and Disease
The G2385R variant of the leucine-rich repeat kinase 2 (LRRK2) is strongly associated with Parkinson's disease (PD) in Asian populations. However, it is still unclear whether the clinical phenotype of PD patients with the G2385R variant can be distin
Publikováno v:
Progress in neurobiology. 147
Oxidative stress reflects an imbalance between the overproduction and incorporation of free radicals and the dynamic ability of a biosystem to detoxify reactive intermediates. Free radicals produced by oxidative stress are one of the common features