Zobrazeno 1 - 10
of 15
pro vyhledávání: '"Tian-Fang Chang"'
Publikováno v:
Guoji Yanke Zazhi, Vol 23, Iss 11, Pp 1775-1780 (2023)
AIM: To investigate the effects of antitumor drug paclitaxel(PTX)on the proliferation, apoptosis, cell cycle, cell morphology, and related protein expression of Müller cells, and to evaluate its potential toxicity to the retina.METHODS:Müller cells
Externí odkaz:
https://doaj.org/article/54b9bc7e9d684a05aef6c59a4feefab4
Autor:
Zi-Yi Zhou, Tian-Fang Chang, Zhi-Bin Lin, Yu-Tong Jing, Li-Shi Wen, Ya-Li Niu, Qian Bai, Chang-Mei Guo, Jia-Xing Sun, Yu-Sheng Wang, Guo-Rui Dou
Publikováno v:
Cell Death and Disease, Vol 14, Iss 6, Pp 1-15 (2023)
Abstract Microglia were considered as immune cells in inflammation until their angiogenic role was widely understood. Although the pro-inflammatory role of microglia in retinal angiogenesis has been explored, little is known about its role in pro-ang
Externí odkaz:
https://doaj.org/article/5c6ff25cee404415ac2fd54247c7ceab
Publikováno v:
Guoji Yanke Zazhi, Vol 22, Iss 2, Pp 194-199 (2022)
AIM: To investigate the potential toxic effects of paclitaxel(PTX)on the proliferation, apoptosis, cell cycle, morphology, and blood-retinal barrier(BRB)of human retinal pigment epithelial cells(ARPE-19). METHODS: ARPE-19 cells were cultured in vitro
Externí odkaz:
https://doaj.org/article/de3ffeb280f4474ca4cf72bd1114c1ce
Autor:
Jia-Xing Sun, Guo-Rui Dou, Zi-Yan Yang, Liang Liang, Juan-Li Duan, Bai Ruan, Man-Hong Li, Tian-Fang Chang, Xin-Yuan Xu, Juan-Juan Chen, Yu-Sheng Wang, Xian-Chun Yan, Hua Han
Publikováno v:
Molecular Therapy: Nucleic Acids, Vol 25, Iss , Pp 554-566 (2021)
After angiogenesis-activated embryonic and early postnatal vascularization, endothelial cells (ECs) in most tissues enter a quiescent state necessary for proper tissue perfusion and EC functions. Notch signaling is essential for maintaining EC quiesc
Externí odkaz:
https://doaj.org/article/6b355598f6fc466e98e22b4d43c3b38d
Autor:
Xian‐Chun Yan, Jing Cao, Liang Liang, Li Wang, Fang Gao, Zi‐Yan Yang, Juan‐Li Duan, Tian‐Fang Chang, San‐Ming Deng, Yuan Liu, Guo‐Rui Dou, Jian Zhang, Qi‐Jun Zheng, Ping Zhang, Hua Han
Publikováno v:
Journal of the American Heart Association: Cardiovascular and Cerebrovascular Disease, Vol 5, Iss 2 (2016)
BackgroundEndothelial cells (ECs) form blood vessels through angiogenesis that is regulated by coordination of vascular endothelial growth factor (VEGF), Notch, transforming growth factor β, and other signals, but the detailed molecular mechanisms r
Externí odkaz:
https://doaj.org/article/eef58ee14aa048468431e50968e09608
Autor:
Manhong Li, Guo-Rui Dou, Juan-Juan Chen, Bai Ruan, Jia-Xing Sun, Liang Liang, Hua Han, Xin-Yuan Xu, Zi-Yan Yang, Tian-Fang Chang, Juan-Li Duan, Xian-Chun Yan, Yusheng Wang
Publikováno v:
Molecular Therapy. Nucleic Acids
Molecular Therapy: Nucleic Acids, Vol 25, Iss, Pp 554-566 (2021)
Molecular Therapy: Nucleic Acids, Vol 25, Iss, Pp 554-566 (2021)
After angiogenesis-activated embryonic and early postnatal vascularization, endothelial cells (ECs) in most tissues enter a quiescent state necessary for proper tissue perfusion and EC functions. Notch signaling is essential for maintaining EC quiesc
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a4e7508a41354581fd1fbf8d755a3dad
https://doi.org/10.1016/j.omtn.2021.07.023
https://doi.org/10.1016/j.omtn.2021.07.023
Autor:
Wei Ye, Yafen Wang, Yan-Nian Hui, Tong Wu, Guo-Rui Dou, Hong-Jun Du, Chang-Mei Guo, Yusheng Wang, Tian-Fang Chang
Publikováno v:
Molecular Medicine Reports
Proliferative vitreoretinopathy (PVR) is a disease leading to the formation of contractile preretinal membranes (PRMs) and is one of the leading causes of blindness. Connective tissue growth factor (CTGF) has been identified as a possible key determi
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4a5ea08517f65ceb50eb46567b7f1d6d
https://pubmed.ncbi.nlm.nih.gov/33760200
https://pubmed.ncbi.nlm.nih.gov/33760200
Autor:
Hua Han, Zi-Yan Yang, Tian-Fang Chang, Juan-Li Duan, San-Ming Deng, Li Wang, Liang Liang, Qijun Zheng, Yuan Liu, Bai Ruan, Xian-Chun Yan
Publikováno v:
Biochemical and Biophysical Research Communications. 483:488-494
Although it has been suggested that Dll3, one of the Notch ligands, promotes the proliferation and inhibits the apoptosis of cancer cells, the role of Dll3 in cancers remains unclear. In this study, we found that in the murine Lewis lung carcinoma (L
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::232a25093f560ecf82fedf15877ba931
https://doi.org/10.1016/j.bbrc.2016.12.117
https://doi.org/10.1016/j.bbrc.2016.12.117
Publikováno v:
Cell and tissue research. 380(3)
Macrophages promote vasculogenesis during retinal neovascularization (RNV) by increasing the recruitment and differentiation of bone marrow-derived cells (BMCs). Different subtypes of macrophages (M1 and M2 macrophages) are associated with RNV. Howev
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::cc24ada928623c9f2526d21a60a6dece
https://pubmed.ncbi.nlm.nih.gov/31989253
https://pubmed.ncbi.nlm.nih.gov/31989253
Autor:
Hong Li, Wen-Gang Dong, Tian-Fang Chang, Guo-Rui Dou, Xiao-Yan Pan, Jia-Xing Sun, Manhong Li, Wenqin Xu, Yang Lv, Li-Juan Sun, Yusheng Wang
Publikováno v:
Experimental eye research. 193
Choroidal neovascularization (CNV) is an acknowledged pathogenic mechanism of various ocular diseases, and in situ cells and mobilized bone marrow-derived cells (BMCs) are thought to participate in this process. We aimed to evaluate the roles of inte
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b0120762a9ffa5f3bb7537ee06ddab5f
https://pubmed.ncbi.nlm.nih.gov/32142723
https://pubmed.ncbi.nlm.nih.gov/32142723