Zobrazeno 1 - 10
of 17
pro vyhledávání: '"Tian X. Zhao"'
Autor:
Akimichi Inaba, Zewen Kelvin Tuong, Tian X. Zhao, Andrew P. Stewart, Rebeccah Mathews, Lucy Truman, Rouchelle Sriranjan, Jane Kennet, Kourosh Saeb-Parsy, Linda Wicker, Frank Waldron-Lynch, Joseph Cheriyan, John A. Todd, Ziad Mallat, Menna R. Clatworthy
Publikováno v:
Nature Communications, Vol 14, Iss 1, Pp 1-11 (2023)
Abstract Dysfunction of interleukin-10 producing regulatory B cells has been associated with the pathogenesis of autoimmune diseases, but whether regulatory B cells can be therapeutically induced in humans is currently unknown. Here we demonstrate th
Externí odkaz:
https://doaj.org/article/733547fe76a040a4be8f3da2878d86c9
Autor:
Muhammad Aetesam-ur-Rahman, Joel P. Giblett, Bharat Khialani, Stephen Kyranis, Sophie J. Clarke, Tian X. Zhao, Denise M. Braganza, Sarah C. Clarke, Nick E. J. West, Martin R. Bennett, Stephen P. Hoole
Publikováno v:
BMC Cardiovascular Disorders, Vol 21, Iss 1, Pp 1-9 (2021)
Abstract Background Incretin therapies appear to provide cardioprotection and improve cardiovascular outcomes in patients with diabetes, but the mechanism of this effect remains elusive. We have previously shown that glucagon-like peptide (GLP)-1 is
Externí odkaz:
https://doaj.org/article/d286fb542d1246fc8a722b0a04ccca0b
Autor:
Muhammad Aetesam‐ur‐Rahman, Tian X. Zhao, Kitty Paques, Joana Oliveira, Bharat Khialani, Stephen Kyranis, Denise M. Braganza, Sarah C. Clarke, Martin R. Bennett, Nick E. J. West, Stephen P. Hoole
Publikováno v:
Journal of the American Heart Association: Cardiovascular and Cerebrovascular Disease, Vol 11, Iss 9 (2022)
Background Post–percutaneous coronary intervention (PCI) fractional flow reserve ≥0.90 is an accepted marker of procedural success, and a cutoff of ≥0.95 has recently been proposed for post‐PCI instantaneous wave‐free ratio. However, stabil
Externí odkaz:
https://doaj.org/article/511ad4b921144eb2af6456dc040dda07
Autor:
Muhammad Aetesam‐ur‐Rahman, Adam J. Brown, Catherine Jaworski, Joel P. Giblett, Tian X. Zhao, Denise M. Braganza, Sarah C. Clarke, Bobby S. K. Agrawal, Martin R. Bennett, Nick E. J. West, Stephen P. Hoole
Publikováno v:
Journal of the American Heart Association: Cardiovascular and Cerebrovascular Disease, Vol 10, Iss 13 (2021)
Background Adenosine is used to treat no‐reflow in the infarct‐related artery (IRA) during ST‐segment–elevation myocardial infarction intervention. However, the physiological effect of adenosine in the IRA is variable. Coronary steal—a redu
Externí odkaz:
https://doaj.org/article/a277b79727b44ff2b4e9731824378745
Autor:
Tian X. Zhao, Ziad Mallat
Publikováno v:
Nature Cardiovascular Research. 2:97-99
Autor:
Simon Bond, Joseph Cheriyan, Jean-Sébastien Silvestre, Brian Y.H. Lam, Yanyi Sun, James H.F. Rudd, Yuning Lu, Marcella Ma, Ziad Mallat, Meritxell Nus, James Harrison, Rouchelle Sriranjan, Andrew S. Sage, Xian Yu, Stephen A. Newland, Tian X. Zhao, Xiang Cheng
Publikováno v:
Journal of the American College of Cardiology. 78:1127-1142
BACKGROUND: Innate lymphoid cells type 2 (ILC2s) play critical homeostatic functions in peripheral tissues. ILC2s reside in perivascular niches and limit atherosclerosis development. OBJECTIVES: ILC2s also reside in the pericardium but their role in
Autor:
Andrew P. Sage, Tian X. Zhao, Laia Cros-Brunsó, James Harrison, Dimitrios Tsiantoulas, Ziad Mallat, Frederic Geissmann, Leanne Masters, Meritxell Nus, Christoph J. Binder, Nichola Figg, María Galán, Gemma Basatemur
Publikováno v:
Arteriosclerosis, Thrombosis, and Vascular Biology
Supplemental Digital Content is available in the text.
Objective: NR4A orphan receptors have been well studied in vascular and myeloid cells where they play important roles in the regulation of inflammation in atherosclerosis. NR4A1 (nerve growt
Objective: NR4A orphan receptors have been well studied in vascular and myeloid cells where they play important roles in the regulation of inflammation in atherosclerosis. NR4A1 (nerve growt
Publikováno v:
European Heart Journal. 42
Introduction Fabry disease is a lysosomal storage disorder resulting in multisystemic effects due to deposition and accumulation of glycosphingolipids. Although an X linked disorder, it is recognised that female heterozygotes can express clinical man
Autor:
Martin R. Bennett, Nick E.J. West, Muhammad Aetesam-Ur-Rahman, Bobby Agrawal, Stephen P. Hoole, Catherine Jaworski, Adam J. Brown, Tian X. Zhao, Denise Braganza, Joel P. Giblett, Sarah C. Clarke
Publikováno v:
Journal of the American Heart Association. 10
Background Adenosine is used to treat no‐reflow in the infarct‐related artery (IRA) during ST‐segment–elevation myocardial infarction intervention. However, the physiological effect of adenosine in the IRA is variable. Coronary steal—a redu
Autor:
Ziad Mallat, Tian X. Zhao
Publikováno v:
Journal of the American College of Cardiology. 73:1691-1706
Atherosclerosis has long been known as an inflammatory disease. However, whether targeting inflammation improves outcomes was unproven until the recent results of CANTOS (Canakinumab Anti-Inflammatory Thrombosis Outcomes Study). In this review, we re