Zobrazeno 1 - 10
of 19
pro vyhledávání: '"Tian Min Chen"'
Autor:
Xiaojia Guo, Valerie Blanc, Nicholas O. Davidson, Heino Velazquez, Tian-min Chen, Dennis G. Moledina, Gilbert W. Moeckel, Robert L. Safirstein, Gary V. Desir
Publikováno v:
Scientific Reports, Vol 13, Iss 1, Pp 1-14 (2023)
Abstract Cisplatin (CP) induces acute kidney injury (AKI) whereby proximal tubules undergo regulated necrosis. Repair is almost complete after a single dose. We now demonstrate a role for Apolipoprotein B mRNA editing enzyme, catalytic polypeptide 1
Externí odkaz:
https://doaj.org/article/cbd6c09daa0349ee9f062655e85219b0
Autor:
Yasheen Gao, Melinda Wang, Xiaojia Guo, Joanna Hu, Tian-Min Chen, Sade M B Finn, Jill Lacy, John W Kunstman, Charles H Cha, Melena D Bellin, Marie E Robert, Gary V Desir, Fred S Gorelick
Publikováno v:
PLoS ONE, Vol 16, Iss 9, p e0250539 (2021)
Dysregulated expression of the secretory protein renalase can promote pancreatic ductal adenocarcinoma (PDAC) growth in animal models. We characterized renalase expression in premalignant and malignant PDAC tissue and investigated whether plasma rena
Externí odkaz:
https://doaj.org/article/df608288a0c2416eaf83a695166bb52d
Autor:
Xiaojia Guo, Leyuan Xu, Heino Velazquez, Tian-Min Chen, Ryan M. Williams, Daniel A. Heller, Barbara Burtness, Robert Safirstein, Gary V. Desir
Publikováno v:
J Am Soc Nephrol
Repeated administration of cisplatin causes CKD. In previous studies, we reported that the kidney-secreted survival protein renalase (RNLS) and an agonist peptide protected mice from cisplatin-induced AKI.To investigate whether kidney-targeted delive
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3cb19dcae7016e2e5e613f13d72f23d0
https://doi.org/10.1681/asn.2021040439
https://doi.org/10.1681/asn.2021040439
Autor:
Fred S. Gorelick, John W. Kunstman, Charles Cha, Yasheen Gao, Jill Lacy, Xiaojia Guo, Sade´ M. B. Finn, Melinda Wang, Gary V. Desir, Tian-min Chen, Joanna Hu, Melena D. Bellin, Marie E. Robert
Publikováno v:
PLoS ONE, Vol 16, Iss 9, p e0250539 (2021)
PLoS ONE
PLoS ONE
Dysregulated expression of the secretory protein renalase can promote pancreatic ductal adenocarcinoma (PDAC) growth in animal models. We characterized renalase expression in premalignant and malignant PDAC tissue and investigated whether plasma rena
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1be7feca7b255d8f7e4853ac29fceee0
https://doi.org/10.1371/journal.pone.0250539
https://doi.org/10.1371/journal.pone.0250539
Autor:
Yang Wang, Lindsay Hollander, Heino Velazquez, John T. Chang, Robert Safirstein, Gary V. Desir, Jian‐jun Mu, Tian-Min Chen, Xiao-Jia Guo
Publikováno v:
Journal of Cellular and Molecular Medicine
Renalase was discovered as a protein synthesized by the kidney and secreted in blood where it circulates at a concentration of approximately 3–5 μg/ml. Initial reports suggested that it functioned as an NAD(P)H oxidase and could oxidize catecholam
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5f485e4de22207d40620337addc6f3ef
https://doi.org/10.1111/jcmm.13062
https://doi.org/10.1111/jcmm.13062
Publikováno v:
Nucleic Acids Research
Therapeutic small interfering RNAs (siRNAs) are composed of chemically modified nucleotides, which enhance RNA stability and increase affinity in Watson-Crick base pairing. However, the precise fate of such modified nucleotides once the siRNA is degr
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::262a2d341de03658e518fe2bcbb158ef
https://doi.org/10.1093/nar/gkt120
https://doi.org/10.1093/nar/gkt120
Publikováno v:
Journal of Laparoendoscopic & Advanced Surgical Techniques. 19:405-408
The aim of this study was to evaluate the effect of a self-releasing biliary stent antegradely placed during laparoscopic common bile duct exploration (LCBDE) for choledocholithiasis.The soft biliary stent, made of polyurethane, was designed as a J-u
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::305cbf217a6ab5a56e00308ef1c1c477
https://doi.org/10.1089/lap.2008.0048
https://doi.org/10.1089/lap.2008.0048
Publikováno v:
Biochemical and Biophysical Research Communications. 369:795-800
Human dihydrofolate reductase (DHFR) is a critical target in cancer chemotherapy. Previous studies showed that an 82-nt RNA fragment within the DHFR mRNA protein-coding region functions as a DHFR cis-acting response element. In this study, we further
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b6ba45f992e90700c605c104b2a27349
https://doi.org/10.1016/j.bbrc.2007.09.044
https://doi.org/10.1016/j.bbrc.2007.09.044
Autor:
Wu Yan, Ningwen Tai, Jun Liu, Michael H. Farrell, John C. Schmitz, Michelle Bailly, Edward Chu, Tian Min Chen, Xiukun Lin
Publikováno v:
Biochimica et Biophysica Acta (BBA) - Molecular Basis of Disease. 1587(2-3):174-182
Studies from our laboratory have shown that the folate-dependent enzyme, thymidylate synthase (TS), functions as an RNA binding protein. There is evidence that TS, in addition to interacting with its own TS mRNA, forms a ribonucleoprotein complex wit
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a71b1357e54b050fdeea3d3da6f8410a
Autor:
Wu Yan, John C. Schmitz, Xiukun Lin, Ashwin Gollerkeri, Edward Chu, Tian Min Chen, Ningwen Tai, Jun Liu
Publikováno v:
Cancer and Metastasis Reviews. 20:33-41
Cellular drug resistance is one of the principal obstacles to the clinical efficacy of cancer chemotherapy. In this review, we describe the potential role for translational regulation as a novel mechanism for modulating chemosensitivity. The evidence
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::f73fcffed0e4a856554f3c0068b9c307
https://doi.org/10.1023/a:1013100306315
https://doi.org/10.1023/a:1013100306315