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ZNT1 and Zn 2+ control TLR4 and PD-L1 endocytosis in macrophages to improve chemotherapy efficacy against liver tumor.

Autor: Yang D; State Key Laboratory of Virology, Wuhan Institute of Virology, Chinese Academy of Sciences, Wuhan, China.; School of Life Sciences, Shanghai University, Shanghai, China.; University of Chinese Academy of Sciences, Beijing, China., Tian T; School of Life Sciences, Shanghai University, Shanghai, China., Li X; School of Life Sciences, Shanghai University, Shanghai, China., Zhang B; School of Life Sciences, Shanghai University, Shanghai, China., Qi L; State Key Laboratory of Virology, Wuhan Institute of Virology, Chinese Academy of Sciences, Wuhan, China.; School of Life Sciences, Shanghai University, Shanghai, China.; University of Chinese Academy of Sciences, Beijing, China., Zhang F; State Key Laboratory of Virology, Wuhan Institute of Virology, Chinese Academy of Sciences, Wuhan, China.; Cancer Center, Shanghai Tenth People's Hospital, School of Medicine, Tongji University, Shanghai, China., Han M; State Key Laboratory of Cell Biology, Shanghai Institute of Biochemistry and Cell Biology, Center for Excellence in Molecular Cell Science, Chinese Academy of Sciences, Shanghai, China., Wang S; State Key Laboratory of Cell Biology, Shanghai Institute of Biochemistry and Cell Biology, Center for Excellence in Molecular Cell Science, Chinese Academy of Sciences, Shanghai, China., Xiao J; State Key Laboratory of Cell Biology, Shanghai Institute of Biochemistry and Cell Biology, Center for Excellence in Molecular Cell Science, Chinese Academy of Sciences, Shanghai, China., Gou Y; School of Life Sciences, Shanghai University, Shanghai, China., Zhang R; State Key Laboratory of Virology, Wuhan Institute of Virology, Chinese Academy of Sciences, Wuhan, China.; University of Chinese Academy of Sciences, Beijing, China., Liu Q; State Key Laboratory of Virology, Wuhan Institute of Virology, Chinese Academy of Sciences, Wuhan, China.; University of Chinese Academy of Sciences, Beijing, China., Su S; Department of Liver Surgery and Transplantation, Liver Cancer Institute, Zhongshan Hospital, Fudan University, Shanghai, China., Liu J; State Key Laboratory of Genetic Engineering, Zhongshan Hospital and School of Life Sciences, Metabolomics and Systems Biology Laboratory, Human Phenome Institute, Fudan University, Shanghai, China., Huang X; Department of Liver Surgery and Transplantation, Liver Cancer Institute, Zhongshan Hospital, Fudan University, Shanghai, China., Gao Q; Department of Liver Surgery and Transplantation, Liver Cancer Institute, Zhongshan Hospital, Fudan University, Shanghai, China., Hui L; University of Chinese Academy of Sciences, Beijing, China.; State Key Laboratory of Cell Biology, Shanghai Institute of Biochemistry and Cell Biology, Center for Excellence in Molecular Cell Science, Chinese Academy of Sciences, Shanghai, China.; School of Life Science, Hangzhou Institute for Advanced Study, University of Chinese Academy of Sciences, Hangzhou, China., Tang H; State Key Laboratory of Genetic Engineering, Zhongshan Hospital and School of Life Sciences, Metabolomics and Systems Biology Laboratory, Human Phenome Institute, Fudan University, Shanghai, China., Chen Y; State Key Laboratory of Coordination Chemistry, Chemistry and Biomedicine Innovation Center (ChemBIC ), School of Chemistry and Chemical Engineering, Nanjing University., Wang H; University of Chinese Academy of Sciences, Beijing, China.; State Key Laboratory of Cell Biology, Shanghai Institute of Biochemistry and Cell Biology, Center for Excellence in Molecular Cell Science, Chinese Academy of Sciences, Shanghai, China.; School of Life Science, Hangzhou Institute for Advanced Study, University of Chinese Academy of Sciences, Hangzhou, China., Wei B; State Key Laboratory of Virology, Wuhan Institute of Virology, Chinese Academy of Sciences, Wuhan, China.; School of Life Sciences, Shanghai University, Shanghai, China.; University of Chinese Academy of Sciences, Beijing, China.; Cancer Center, Shanghai Tenth People's Hospital, School of Medicine, Tongji University, Shanghai, China.

Publikováno v: Hepatology (Baltimore, Md.) [Hepatology] 2024 Aug 01; Vol. 80 (2), pp. 312-329. Date of Electronic Publication: 2023 Oct 09.