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Akademický článek

Genetic Variants Underlying Risk of Intracranial Aneurysms: Insights from a GWAS in Portugal.

Autor: Patrícia Abrantes, Maria M Santos, Inês Sousa, Joana M Xavier, Vânia Francisco, Tiago Krug, João Sobral, Mafalda Matos, Madalena Martins, António Jacinto, Domingos Coiteiro, Sofia A Oliveira

Publikováno v: PLoS ONE, Vol 10, Iss 7, p e0133422 (2015)

Subarachnoid hemorrhage (SAH) is a life-threatening event that most frequently leads to severe disability and death. Its most frequent cause is the rupture of a saccular intracranial aneurysm (IA), which is a blood vessel dilation caused by disease o

Externí odkaz: https://doaj.org/article/f37417765fe94084ac51b63e5abb7cd5

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Variants in the Inflammatory IL6 and MPO Genes Modulate Stroke Susceptibility Through Main Effects and Gene—Gene Interactions

Autor: Isabel Albergaria, José M. Ferro, Astrid M. Vicente, Helena Manso, Sofia A. Oliveira, Gisela Gaspar, Tiago Krug, João Sobral

Publikováno v: Journal of Cerebral Blood Flow & Metabolism. 31:1751-1759

There is substantial evidence that inflammation within the central nervous system contributes to stroke risk and recovery. Inflammatory conditions increase stroke risk, and the inflammatory response is of major importance in recovery and healing proc

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::76426544f27bd7f81a9a3b0aab88da67
https://doi.org/10.1038/jcbfm.2011.27

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Association of a Genetic Variant in the ALOX5AP with Higher Risk of Ischemic Stroke: A Case-Control, Meta-Analysis and Functional Study

Publikováno v: Cerebrovascular Diseases. 29:528-537

Background: Variants in the 5-lipoxygenase-activating protein (ALOX5AP) and phosphodiesterase 4D (PDE4D) genes have first been associated with ischemic stroke (IS) through whole-genome linkage screens. However, association studies obtained conflictin

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::7ed5bb6f7602019637ca50760c2f5ffd
https://doi.org/10.1159/000302738

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Poorly differentiated and anaplastic thyroid carcinomas: chromosomal and oligo-array profile of five new cell lines

Autor: Tiago Krug, Valeriano Leite, Raquel Rodrigues, Lúcia Roque

Publikováno v: British Journal of Cancer

Information on gene alterations associated to poorly differentiated (PDTC) and anaplastic thyroid carcinomas (ATC) is scarce. Using human cancer cell lines as a tool for gene discovery, we performed a cytogenetic and oligo-array analysis in five new

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::19876118d7dba0b55ed302f9ddca446d
http://europepmc.org/articles/PMC2360140

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Genetic variants underlying risk of intracranial aneurysms: Insights from a GWAS in Portugal

Autor: António Jacinto, Tiago Krug, João Sobral, Inês Sousa, Patrícia Abrantes, Mafalda Matos, Domingos Coiteiro, Joana M. Xavier, Madalena Martins, Vânia Francisco, Maria M. M. Santos, Sofia Oliveira

Publikováno v: Repositório Científico de Acesso Aberto de Portugal
Repositório Científico de Acesso Aberto de Portugal (RCAAP)
instacron:RCAAP
PLoS ONE, Vol 10, Iss 7, p e0133422 (2015)
PLoS ONE

This work was supported by the Fundacao para a Ciencia e Tecnologia (FCT-Portugal) through several grants (PTDC/SAU-GMG/101537/2008, PTDC/IIM-GES/5015/2012 and CMUP-ERI/TPE/0028/2013), fellowships and research contracts (SFRH/BPD/35737/2007 to PA, SF

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a329ba3aee5766ae4b42d290b7b0bd82
https://hdl.handle.net/10362/21490

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Evidence for epistatic gene interactions between growth factor genes in stroke outcome

Autor: Helena Manso, Gisela Gaspar, José M. Ferro, João Sobral, Sofia A. Oliveira, Tiago Krug, Isabel Albergaria, Astrid M. Vicente

Publikováno v: European Journal of Neurology. 19:1151-1153

Background and purpose: Growth factors are thought to modulate neurological function in stroke recovery through effects in angiogenesis, neurogenesis, and neuroprotection. Methods: We tested the association of variants in the brain-derived neurotroph

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::d5bb3f4c27f6807b82b4414309367149
https://doi.org/10.1111/j.1468-1331.2011.03625.x

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Subject Index Vol. 29, 2010

Autor: Christopher F. Bladin, D. Dormont, Masafumi Harada, Astrid M. Vicente, Kenneth Butcher, Delphine Michel-Monigadon, Kristina Szabo, Sofia A. Oliveira, Marta Rubiera, Heinz G. Endres, Jeroen Hendrikse, Sophie Domingues-Montanari, Klaus Berger, S. Crozier, Marc Ribó, Gerhart Tepohl, Natalia Corbeto, Marimar Freijo, Christophe Bonny, Joan Martí-Fàbregas, Christopher R Levi, A. Drier, K.M. Kasius, Jens-Rainer Allenberg, Nikolai Steffenhagen, G.J.E. Rinkel, Jessica Fernández-Morales, Joan Montaner, C. van Heugten, Willem P.Th.M. Mali, Bruce Ovbiagele, Imanuel Dzialowski, Dirk Sander, Naomi Morita, S. Deltour, Ryuuji Kaji, Junichiro Satomi, Maite Mendioroz, Georg Bohner, Joaquín Serena, Angelika Alonso, Lorenz Hirt, M. Coudert, Shelagh B. Coutts, Hiromu Nishitani, C.J.M. Frijns, Stephen M. Davis, Jochen B. Fiebach, José Alvarez-Sabín, P. Renou, D. Galanaud, Kotaro Asanuma, Israel Fernandez-Cadenas, Masaaki Uno, Roman L. Haberl, Geoffrey A. Donnan, A. Algra, Soren Christensen, Stefano Ricci, Markus Schwertfeger, Sarah J. Foster, P. Alan Barber, Curt Diehm, Ina Burghaus, Helena Manso, Saskia H. Meves, Patricia Desmond, David Pittrow, Michael G. Hennerici, José M. Ferro, Y. Samson, T. Tourdias, Andrew M. Demchuk, Meng Lee, Victor Obach, Alberto del Rio-Espinola, Frans L. Moll, Lisa M. Jongen, Christine O'Reilly, Shinji Nagahiro, H. Bart van der Worp, João Sobral, Volker Puetz, M.W.M. Post, Bruce C.V. Campbell, Tiago Krug, M.J.E. van Zandvoort, I. Sibon, Stefan H. Kreisel, C. Rosso, J.M.A. Visser-Meily, Harald Darius, Liliana Gouveia, P.E.C.A. Passier, F. Rouanet, Michael D. Hill, Yuishin Izumi, Mark W Parsons, Hans-Joachim Trampisch

Publikováno v: Cerebrovascular Diseases. 29:614-616

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::8bb75388434e3a9f6816219c56efe871
https://doi.org/10.1159/000314828

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Gene expression profiling and association studies implicate the neuregulin signaling pathway in Behçet's disease susceptibility

Autor: Fahmida Ghaderibarmi, Joana Vedes, Joana M. Xavier, Jorge Crespo, Bahar Sadeghi Abdollahi, Farhad Shahram, Sofia A. Oliveira, Benedita V. Fonseca, Gorete Jesus, Filipe Barcelos, Niloofar Mojarad Shafiee, Tiago Krug, Maria Francisca Moraes-Fontes, Manuel Salgado, Abdolhadi Nadji, Fereydoun Davatchi, José Vaz Patto

Publikováno v: Repositório Científico de Acesso Aberto de Portugal
Repositório Científico de Acesso Aberto de Portugal (RCAAP)
instacron:RCAAP
Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos)
Agência para a Sociedade do Conhecimento (UMIC)-FCT-Sociedade da Informação
Europe PubMed Central

© Springer-Verlag Berlin Heidelberg 2013
Behçet's disease (BD) is a complex disease with genetic and environmental risk factors implicated in its etiology; however, its pathophysiology is poorly understood. To decipher BD's genetic underpinnin

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c4c90570ddf1aae940f3b503a540d9af

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