Zobrazeno 1 - 10
of 32
pro vyhledávání: '"Tiago J. Costa"'
Autor:
Luiz Felipe Martucci, Rosangela A.S. Eichler, Renée N.O. Silva, Tiago J. Costa, Rita C. Tostes, Geraldo F. Busatto, Marilia C.L. Seelaender, Alberto J.S. Duarte, Heraldo P. Souza, Emer S. Ferro
Publikováno v:
iScience, Vol 26, Iss 9, Pp 107542- (2023)
Summary: Intracellular peptides (InPeps) generated by the orchestrated action of the proteasome and intracellular peptidases have biological and pharmacological significance. Here, human plasma relative concentration of specific InPeps was compared b
Externí odkaz:
https://doaj.org/article/ed16d2f3b9724f018b9b9ae7854fda46
Autor:
Tiago J. Costa, Júlio Cezar De Oliveira, Fernanda Regina Giachini, Victor Vitorino Lima, Rita C. Tostes, Gisele Facholi Bomfim
Publikováno v:
Frontiers in Physiology, Vol 13 (2022)
A growing body of evidence highlights that several insults during pregnancy impact the vascular function and immune response of the male and female offspring. Overactivation of the immune system negatively influences cardiovascular function and contr
Externí odkaz:
https://doaj.org/article/64f2944e77514d019610067a4997260f
Publikováno v:
Frontiers in Aging, Vol 2 (2021)
Increasing scientific interest has been directed to sex as a biological and decisive factor on several diseases. Several different mechanisms orchestrate vascular function, as well as vascular dysfunction in cardiovascular and metabolic diseases in m
Externí odkaz:
https://doaj.org/article/87e65d68b1314f29ac667f0b0ee74c19
Autor:
Tiago J. Costa, Josiane F. Silva, Renée de Nazaré O. da Silva, Paula R. Barros, Juliana Bolsoni, Daniel Rodrigues, Eliana H. Akamine, Rita Tostes
Publikováno v:
Artery Research, Vol 25, Iss 1 (2020)
The glycosylation with O-linked-N-acetylglucosamine (O-GlcNAc) is an enzymatic process found on nuclear and cytoplasmic proteins. Augmented levels of O-GlcNAc-modified proteins have been associated to cardiovascular disease (CD) in male. However, the
Externí odkaz:
https://doaj.org/article/4b61a77854cc44c5ab704496ee59139c
Autor:
Daniel Rodrigues, Tiago J. Costa, Josiane F. Silva, José Teles de Oliveira Neto, Juliano V. Alves, Aline G. Fedoce, Rafael Menezes Costa, Rita C. Tostes
Publikováno v:
International Journal of Molecular Sciences, Vol 22, Iss 11, p 6154 (2021)
High levels of aldosterone (Aldo) trigger oxidative stress and vascular dysfunction independent of effects on blood pressure. We sought to determine whether Aldo disrupts Nrf2 signaling, the main transcriptional factor involved in antioxidant respons
Externí odkaz:
https://doaj.org/article/9685e41940d94f83817e1ed3443f4d77
Autor:
Tiago J. Costa, Graziela S. Ceravolo, Cinthya Echem, Carolina M. Hashimoto, Beatriz P. Costa, Rosangela A. Santos-Eichler, Maria Aparecida Oliveira, Francesc Jiménez-Altayó, Eliana H. Akamine, Ana Paula Dantas, Maria Helena C. Carvalho
Publikováno v:
Frontiers in Physiology, Vol 9 (2018)
Postmenopausal period has been associated to different symptoms such as hot flashes, vulvovaginal atrophy, hypoactive sexual desire disorder (HSDD) and others. Clinical studies have described postmenopausal women presenting HSDD can benefit from the
Externí odkaz:
https://doaj.org/article/a1dbf904d2e1496395afad85210092a7
Autor:
Tiago J. Costa, Paula R. Barros, Diego A. Duarte, Júlio A. Silva-Neto, Sara Cristina Hott, Thamyris Santos-Silva, Claudio M. Costa-Neto, Felipe V. Gomes, Eliana H. Akamine, Cameron G. McCarthy, Francesc Jimenez-Altayó, Ana Paula Dantas, Rita C. Tostes
Publikováno v:
American Journal of Physiology-Heart and Circulatory Physiology. 324:H417-H429
The present study provides evidence that senescence induces hyperreactivity of α1-adrenoceptor-mediated contraction of the common carotid. Impairment of α1-adrenoceptor responses is linked to increased Ca2+ influx and release of COX-derived vasocon
Autor:
Tiago J. Costa, Braxton A. Linder, Seth Hester, Milene Fontes, Laena Pernomian, Camilla F. Wenceslau, Austin T. Robinson, Cameron G. McCarthy
Publikováno v:
Journal of Hypertension. 40:2111-2119
Hypertension is the most important risk factor for the development of terminal cardiovascular diseases, such as heart failure, chronic kidney disease, and atherosclerosis. Lifestyle interventions to lower blood pressure are generally desirable prior
Autor:
Tiago J. Costa, Ian Montandon, Emily Wilson, Milene Fontes, Laena Pernomian, Joseph McQuail, Clinton Webb, Wenceslau Camilla, Cameron McCarthy
Publikováno v:
Physiology. 38
Age-associated structural and functional changes in the aorta, including stiffness, loss of elasticity, and reduced vasodilatation, are known to hamper stable peripheral circulation and lead to organ dysfunction. The extracellular matrix (ECM) is a n
Autor:
Luiz Felipe Martucci, Rosangela A. S. Eichler, Tiago J. Costa, Rita C. Tostes, Geraldo F. Busatto, Marilia C.L. Seelaender, Alberto José da Silva Duarte, Heraldo Possolo de Sousa, Emer S. Ferro
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::cb58ac2dd1f4aaa316236b1255c8524c
https://doi.org/10.2139/ssrn.4383075
https://doi.org/10.2139/ssrn.4383075