Zobrazeno 1 - 10
of 21
pro vyhledávání: '"Tiago, Maié"'
Autor:
Kristin Holl, Nicolas Chatain, Susanne Krapp, Julian Baumeister, Tiago Maié, Sarah Schmitz, Anja Scheufen, Nathalie Brock, Steffen Koschmieder, Daniel Moreno-Andrés
Publikováno v:
Scientific Reports, Vol 14, Iss 1, Pp 1-18 (2024)
Abstract Myeloproliferative neoplasms (MPNs) encompass a diverse group of hematologic disorders driven by mutations in JAK2, CALR, or MPL. The prevailing working model explaining how these driver mutations induce different disease phenotypes is based
Externí odkaz:
https://doaj.org/article/16908be3238c4f509fba9b2239b81661
Autor:
Can Bora Yildiz, Tathagata Kundu, Julia Gehrmann, Jannis Koesling, Amin Ravaei, Philip Wolff, Florian Kraft, Tiago Maié, Mira Jakovcevski, Daniel Pensold, Olav Zimmermann, Giulia Rossetti, Ivan G. Costa, Geraldine Zimmer-Bensch
Publikováno v:
Epigenetics & Chromatin, Vol 16, Iss 1, Pp 1-19 (2023)
Abstract Cell–cell communication is mediated by membrane receptors and their ligands, such as the Eph/ephrin system, orchestrating cell migration during development and in diverse cancer types. Epigenetic mechanisms are key for integrating external
Externí odkaz:
https://doaj.org/article/243a1b4e0c1c4caf93c65b9f83fff63e
Publikováno v:
Genome Biology, Vol 24, Iss 1, Pp 1-28 (2023)
Abstract DNA methylation signatures are usually based on multivariate approaches that require hundreds of sites for predictions. Here, we propose a computational framework named CimpleG for the detection of small CpG methylation signatures used for c
Externí odkaz:
https://doaj.org/article/44fe6c4f6b214e30a67685fc48045617
Autor:
Henrike Jacobi, Margherita Vieri, Carolina Y. Namasu, Laura Flüter, Ivan G. Costa, Tiago Maié, Nicolas Chatain, Fabian Beier, Michael Huber, Martina Crysandt, Tim H. Brümmendorf, Mirle Schemionek-Reinders
Publikováno v:
HemaSphere, Vol 7, p e8231722 (2023)
Externí odkaz:
https://doaj.org/article/76f95e3c7a8948be84aeebe6a888ad80
Autor:
Henrike Jacobi, Margherita Vieri, Marlena Bütow, Carolina Y. Namasu, Laura Flüter, Ivan G. Costa, Tiago Maié, Katharina Lindemann-Docter, Nicolas Chatain, Fabian Beier, Michael Huber, Wolfgang Wagner, Martina Crysandt, Tim H. Brümmendorf, Mirle Schemionek
Publikováno v:
Frontiers in Pharmacology, Vol 14 (2023)
The management of patients with chronic myeloid leukemia (CML) has been revolutionized by the introduction of tyrosine kinase inhibitors (TKIs), which induce deep molecular responses so that treatment can eventually be discontinued, leading to treatm
Externí odkaz:
https://doaj.org/article/1bcfdb9e48a74693a9367baef6ba229c
Autor:
Marlena Bütow, Fabio J. Testaquadra, Julian Baumeister, Tiago Maié, Nicolas Chatain, Timo Jaquet, Stefan Tillmann, Martina Crysandt, Ivan G. Costa, Tim H. Brümmendorf, Mirle Schemionek
Publikováno v:
Haematologica, Vol 108, Iss 4 (2022)
Externí odkaz:
https://doaj.org/article/812b73c5e1934e12ae3523cb4a8c88ae
Autor:
Marcelo A. S. de Toledo, Xuhuang Fu, Tiago Maié, Eva M. Buhl, Katrin Götz, Susanne Schmitz, Anne Kaiser, Peter Boor, Till Braunschweig, Nicolas Chatain, Ivan G. Costa, Tim H. Brümmendorf, Steffen Koschmieder, Martin Zenke
Publikováno v:
International Journal of Molecular Sciences, Vol 24, Iss 6, p 5275 (2023)
Mast cells (MCs) represent a population of hematopoietic cells with a key role in innate and adaptive immunity and are well known for their detrimental role in allergic responses. Yet, MCs occur in low abundance, which hampers their detailed molecula
Externí odkaz:
https://doaj.org/article/8f14a930f50b4e6d9eb9211c0b3f5662
Autor:
Claudia Schubert, Manuel Allhoff, Stefan Tillmann, Tiago Maié, Ivan G. Costa, Daniel B. Lipka, Mirle Schemionek, Kristina Feldberg, Julian Baumeister, Tim H. Brümmendorf, Nicolas Chatain, Steffen Koschmieder
Publikováno v:
Journal of Hematology & Oncology, Vol 12, Iss 1, Pp 1-16 (2019)
Abstract Background Interferon alpha (IFNa) monotherapy is recommended as the standard therapy in polycythemia vera (PV) but not in chronic myeloid leukemia (CML). Here, we investigated the mechanisms of IFNa efficacy in JAK2V617F- vs. BCR-ABL-positi
Externí odkaz:
https://doaj.org/article/f04572cd8a7a47c1b8bb12f8129e168b
Autor:
Melanie Langhammer, Julia Schöpf, Timo Jaquet, Katharina Horn, Moritz Angel, Corinna Spohr, Daniel Christen, Franziska Maria Uhl, Tiago Maié, Henrike Jacobi, Thorsten B. Feyerabend, Julia Huber, Marcus Panning, Cassian Sitaru, Ivan Costa, Robert Zeiser, Konrad Aumann, Heiko Becker, Till Braunschweig, Steffen Koschmieder, Khalid Shoumariyeh, Michael Huber, Mirle Schemionek-Reinders, Tilman Brummer, Sebastian Halbach
Publikováno v:
Leukemia.
The persistence of leukemic stem cells (LSCs) represents a problem in the therapy of chronic myeloid leukemia (CML). Hence, it is of utmost importance to explore the underlying mechanisms to develop new therapeutic approaches to cure CML. Using the g
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::e61c6ce08d2879c97feb43239336d547
https://doi.org/10.1038/s41375-023-01916-x
https://doi.org/10.1038/s41375-023-01916-x
Throughout Earth’s natural history, habitats have undergone drastic changes in quality and extent, influencing the distribution of species and their diversity. In the last few hundred years, human activities have destroyed natural habitats at an un
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::148a5036284616a13df2b12db41384f5
https://doi.org/10.1101/2022.10.26.513874
https://doi.org/10.1101/2022.10.26.513874
