Zobrazeno 1 - 6
of 6
pro vyhledávání: '"Tia R. Tidwell"'
Publikováno v:
Cancer Medicine, Vol 13, Iss 11, Pp n/a-n/a (2024)
Abstract Background In vitro drug screening that is more translatable to the in vivo tumor environment can reduce both time and cost of cancer drug development. Here we address some of the shortcomings in screening and show how treatment with 5‐flu
Externí odkaz:
https://doaj.org/article/bfc85fff93b440fda293eb1b3e1ab301
Publikováno v:
Cancer & Metabolism, Vol 10, Iss 1, Pp 1-16 (2022)
Abstract Background Most in vitro cancer cell experiments have been performed using 2D models. However, 3D spheroid cultures are increasingly favored for being more representative of in vivo tumor conditions. To overcome the translational challenges
Externí odkaz:
https://doaj.org/article/47445122c8994eeb9ab62454994fb187
Autor:
Abdelnour H. Alhourani, Tia R. Tidwell, Ansooya A. Bokil, Gro V. Røsland, Karl Johan Tronstad, Kjetil Søreide, Hanne R. Hagland
Publikováno v:
Scientific Reports, Vol 11, Iss 1, Pp 1-10 (2021)
Abstract Cancer cells exhibit altered metabolism, a phenomenon described a century ago by Otto Warburg. However, metabolic drug targeting is considered an underutilized and poorly understood area of cancer therapy. Metformin, a metabolic drug commonl
Externí odkaz:
https://doaj.org/article/6d775d6752384370af9c1a1651d89e30
Autor:
Abdelnour H. Alhourani, Tia R. Tidwell, Ansooya A. Bokil, Gro V. Røsland, Karl Johan Tronstad, Kjetil Søreide, Hanne R. Hagland
Publikováno v:
Scientific Reports, Vol 12, Iss 1, Pp 1-1 (2022)
Externí odkaz:
https://doaj.org/article/f8759eeba33b427bb6ebebb86ad5e97e
Autor:
Gro V. Røsland, Kjetil Søreide, Tia R. Tidwell, Ansooya Avinash Bokil, Abdelnour H. Alhourani, Karl Johan Tronstad, Hanne R. Hagland
Publikováno v:
Scientific Reports
Scientific Reports, Vol 11, Iss 1, Pp 1-10 (2021)
Scientific Reports, Vol 11, Iss 1, Pp 1-10 (2021)
Cancer cells exhibit altered metabolism, a phenomenon described a century ago by Otto Warburg. However, metabolic drug targeting is considered an underutilized and poorly understood area of cancer therapy. Metformin, a metabolic drug commonly used to
Publikováno v:
Aging and Disease
Medical advances made over the last century have increased our lifespan, but age-related diseases are a fundamental health burden worldwide. Aging is therefore a major risk factor for cardiovascular disease, cancer, diabetes, obesity, and neurodegene