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Sarén-Koivuniemi, T J M, Yli-Hankala, A M & van Gils, M 2011, ' Increased variation of the response index of nociception during noxious stimulation in patients during general anaesthesia ', Computer Methods and Programs in Biomedicine, vol. 104, no. 2, pp. 154-160 . https://doi.org/10.1016/j.cmpb.2010.10.001
Objective: Analgesia is an important part of general anaesthesia, but no direct indicators of nociceptive–anti-nociceptive balance have been validated in detail. The Response Index of Nociception (RN) is a multiparameter approach which combines pho