Zobrazeno 1 - 9
of 9
pro vyhledávání: '"Tia Hirvonen"'
Autor:
Saara Laitinen, Tero Satomaa, Annamari Heiskanen, Juhani Saarinen, Sari Tiitinen, Leena Valmu, Annika Kotovuori, Ilja Ritamo, Tia Hirvonen, Heidi Anderson, Jarkko Räbinä, Pertti Sistonen, Suvi Natunen, Heli Suila
Publikováno v:
Stem Cells and Development. 21:455-464
Multipotent mesenchymal stem cells (MSCs) offer great promise for future regenerative and anti-inflammatory therapies. However, there is a lack of methods to quickly and efficiently isolate, characterize, and ex vivo expand desired cell populations f
Autor:
Annamari Heiskanen, Juhani Saarinen, Maria Blomqvist, Leena Valmu, Tia Hirvonen, Johanna Nystedt, Tero Satomaa, Jarmo Laine, Petri Lehenkari, Heidi Anderson, Taina Jaatinen, Jari Natunen, Ulla Impola
Publikováno v:
Stem Cells. 28:258-267
Human stem cells contain substantial amounts of the xenoantigen N-glycolylneuraminic acid (Neu5Gc), although the levels of Neu5Gc are low or undetectable in human body fluids and most other human tissues. The lack of Neu5Gc in human tissues has been
Autor:
Jarkko Räbinä, Jarno Tuimala, Ilja Ritamo, Johanna Nystedt, Tia Hirvonen, Heidi Anderson, Leena Valmu, Suvi Natunen, Heli Suila, Saara Laitinen
Publikováno v:
BioResearch Open Access
BioResearch Open Access, Vol 3, Iss 2, Pp 39-44 (2014)
BioResearch Open Access, Vol 3, Iss 2, Pp 39-44 (2014)
Stem cells have a unique ability to self-renew and differentiate into diverse cell types. Currently, stem cells from various sources are being explored as a promising new treatment for a variety of human diseases. A diverse set of functional and phen
Autor:
Suvi Natunen, Tia Hirvonen, Heli Suila, Leena Valmu, Johanna Nystedt, A. Kotovuori, Saara Laitinen, Ilja Ritamo, Jarkko Räbinä, Jarno Tuimala, Heidi Anderson, Erja Kerkelä
Publikováno v:
Scandinavian journal of immunology. 80(1)
Human multipotent mesenchymal stromal/stem cells (MSCs) have been shown to exert immunomodulatory properties that have great potential in therapies for various inflammatory and autoimmune disorders. However, intravenous delivery of these cells is fol
Autor:
Johanna Nystedt, Siri Lehtonen, Tia Hirvonen, Petri Lehenkari, Heidi Anderson, Tanja Hakkarainen, Leena Valmu, Jonne Tikkanen, Tero Satomaa, Mika Pietilä, Annamari Heiskanen, Matti Korhonen, Reijo Takalo, Suvi Natunen, Saara Laitinen
Publikováno v:
Stem cells (Dayton, Ohio). 31(2)
The promising clinical effects of mesenchymal stromal/stem cells (MSCs) rely especially on paracrine and nonimmunogenic mechanisms. Delivery routes are essential for the efficacy of cell therapy and systemic delivery by infusion is the obvious goal f
Autor:
Anita Laitinen, Tero Satomaa, Leena Valmu, Jari Natunen, Saara Laitinen, Halina Miller-Podraza, Heidi Anderson, Annamari Heiskanen, Tia Hirvonen, Suvi Natunen, Virve Pitkänen, Heli Suila
Publikováno v:
Journal of molecular cell biology. 3(2)
Umbilical cord blood (UCB) is an efficient and valuable source of hematopoietic stem cells (HSCs) for transplantation. In addition to HSCs it harbours low amounts of mesenchymal stem cells (MSCs). No single marker to identify cord blood-derived stem
Autor:
Juhani Saarinen, Leena Valmu, Anita Laitinen, Sari Tiitinen, Tia Hirvonen, Jari Natunen, Manfred Wuhrer, Annamari Heiskanen, Hanna Salo, Jarmo Laine, Tero Satomaa, André M. Deelder, Anne Olonen, Suvi Natunen, Petri Lehenkari, Olli Aitio, Ulla Impola, Halina Miller-Podraza
Publikováno v:
Glycoconjugate journal. 26(3)
Human mesenchymal stem cells (MSCs) are adult multipotent progenitor cells. They hold an enormous therapeutic potential, but at the moment there is little information on the properties of MSCs, including their surface structures. In the present study
Publikováno v:
Journal of leukocyte biology. 82(6)
Lysophosphatidylcholine (LPC) is the most abundant lysophospholipid in plasma and tissues, and its level increases in ischemia and inflammation. LPC induces various proinflammatory actions in leukocytes, endothelial cells, and smooth muscle cells, bu
Autor:
Martin Hermansson, Tia Hirvonen, Ulla Impola, Jaakko Parkkinen, Matti Jauhiainen, Kirsi Polvinen, Martti Tolvanen, Pentti Somerharju, Pauli J. Ojala
Publikováno v:
Biochemistry. 45(47)
Alpha-1 acid glycoprotein (AGP, orosomucoid), a major acute phase protein in plasma, displays potent cytoprotective and anti-inflammatory activities whose molecular mechanisms are largely unknown. Because AGP binds various exogenous drugs, we have se