Zobrazeno 1 - 10
of 23
pro vyhledávání: '"Ti-Hsuan Ku"'
Publikováno v:
Sensors, Vol 15, Iss 7, Pp 16281-16313 (2015)
Detection of small molecules or proteins of living cells provides an exceptional opportunity to study genetic variations and functions, cellular behaviors, and various diseases including cancer and microbial infections. Our aim in this review is to g
Externí odkaz:
https://doaj.org/article/18b2df4b551548acaeb62cd54035a6dd
Autor:
Ti-Hsuan Ku, 顧迪璿
94
Oral squamous cell carcinoma (OSCC) is the 4th leading malignancy in incidence and mortality rate in male population of Taiwan. Previously, our laboratory has found the high expression of lysyl oxidase (LOX) in OSCC tissues. The roles of LOX
Oral squamous cell carcinoma (OSCC) is the 4th leading malignancy in incidence and mortality rate in male population of Taiwan. Previously, our laboratory has found the high expression of lysyl oxidase (LOX) in OSCC tissues. The roles of LOX
Externí odkaz:
http://ndltd.ncl.edu.tw/handle/90985017866989441213
Purpose: Areca nut use is the major cause of oral squamous cell carcinoma (OSCC) in Southern Asians. Areca nut contains a high level of free copper ions. Lysyl oxidase (LOX) is a copper-activated enzyme critical for extracellular matrix organization.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8d55a3573ccfbd1df286debb44747780
https://doi.org/10.1158/1078-0432.c.6518667
https://doi.org/10.1158/1078-0432.c.6518667
Supplementary Methods, Tables 1-3, Figures 1-3 from Association of Expression Aberrances and Genetic Polymorphisms of Lysyl Oxidase with Areca-Associated Oral Tumorigenesis
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::848c844a840c3cb386d40a25a10129f4
https://doi.org/10.1158/1078-0432.22441707.v1
https://doi.org/10.1158/1078-0432.22441707.v1
Publikováno v:
ACS Nano. 9:10655-10663
Nucleic acid detection and quantification technologies have made remarkable progress in recent years. Among existing platforms, hybridization-based assays have the advantages of being amplification free, low instrument cost, and high throughput, but
Publikováno v:
Sensors (Basel, Switzerland)
Sensors, Vol 15, Iss 7, Pp 16281-16313 (2015)
Sensors, Vol 15, Iss 7, Pp 16281-16313 (2015)
Detection of small molecules or proteins of living cells provides an exceptional opportunity to study genetic variations and functions, cellular behaviors, and various diseases including cancer and microbial infections. Our aim in this review is to g
Autor:
Nathan C. Gianneschi, Matthew P. Thompson, Christopher V. Barback, David J. Hall, Ti-Hsuan Ku, Miao-Ping Chien
Publikováno v:
Advanced Materials. 25:3599-3604
The goal of targeted therapeutics and molecular diagnostics is to accumulate drugs or probes at the site of disease in higher quantities relative to other locations in the body. To achieve this, there is tremendous interest in the development of nano
Transient Induced Molecular Electronic Spectroscopy (TIMES) for study of protein-ligand interactions
Autor:
Ramkumar Subramanian, Yu-Hwa Lo, Yuanyuan Han, Hua Luo, Tiantian Zhang, Jian-Jang Huang, Ti-Hsuan Ku, Derrick Chang, Iftikhar Ahmad Niaz
Publikováno v:
Scientific Reports
We present a method, Transient Induced Molecular Electronic Spectroscopy (TIMES), to detect protein-ligand interactions without any protein engineering or chemical modification. We developed a physics model for the TIMES signal and mathematically for
Autor:
Matthew P. Thompson, Norman H. Olson, Ti-Hsuan Ku, Robert S. Sinkovits, Timothy S. Baker, Nathan C. Gianneschi, Miao-Ping Chien
Publikováno v:
Journal of the American Chemical Society. 133:8392-8395
Micelles were prepared from polymer-peptide block copolymer amphiphiles containing substrates for protein kinase A, protein phosphatase-1, and matrix metalloproteinases 2 and 9. We examine reversible switching of the morphology of these micelles thro
Publikováno v:
Journal of Oral Pathology & Medicine. 38:109-113
Objective: Areca use is the major cause for oral squamous cell carcinoma and oral submucous fibrosis (OSF) in South Asians. Lysyl oxidase (LOX) is a copper-activated enzyme critical for collagen cross-linking and organization of extracellular matrix.