Zobrazeno 1 - 10
of 115
pro vyhledávání: '"Ti-Cheng Chang"'
Autor:
Carolyn M Jablonowski, Waise Quarni, Shivendra Singh, Haiyan Tan, Dhanushka Hewa Bostanthirige, Hongjian Jin, Jie Fang, Ti-Cheng Chang, David Finkelstein, Ji-Hoon Cho, Dongli Hu, Vishwajeeth Pagala, Sadie Miki Sakurada, Shondra M Pruett-Miller, Ruoning Wang, Andrew Murphy, Kevin Freeman, Junmin Peng, Andrew M Davidoff, Gang Wu, Jun Yang
Publikováno v:
eLife, Vol 12 (2024)
Dysregulated pre-mRNA splicing and metabolism are two hallmarks of MYC-driven cancers. Pharmacological inhibition of both processes has been extensively investigated as potential therapeutic avenues in preclinical and clinical studies. However, how p
Externí odkaz:
https://doaj.org/article/56c3296c6a1943a796dba4f0a49cdf21
Autor:
Zemin Yang, Bryan A. Johnson, Victoria A. Meliopoulos, Xiaohui Ju, Peipei Zhang, Michael P. Hughes, Jinjun Wu, Kaitlin P. Koreski, Jemma E. Clary, Ti-Cheng Chang, Gang Wu, Jeff Hixon, Jay Duffner, Kathy Wong, Rene Lemieux, Kumari G. Lokugamage, R. Elias Alvarado, Patricia A. Crocquet-Valdes, David H. Walker, Kenneth S. Plante, Jessica A. Plante, Scott C. Weaver, Hong Joo Kim, Rachel Meyers, Stacey Schultz-Cherry, Qiang Ding, Vineet D. Menachery, J. Paul Taylor
Publikováno v:
Cell Reports, Vol 43, Iss 3, Pp 113965- (2024)
Summary: G3BP1/2 are paralogous proteins that promote stress granule formation in response to cellular stresses, including viral infection. The nucleocapsid (N) protein of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) inhibits stress g
Externí odkaz:
https://doaj.org/article/34285ee87dee48f994909c7562854676
Autor:
Michael R. Clay, Anand Patel, Quynh Tran, Dale J. Hedges, Ti-Cheng Chang, Elizabeth Stewart, Greg Charville, Cynthia Cline, Michael A. Dyer, Brent A. Orr
Publikováno v:
Scientific Reports, Vol 11, Iss 1, Pp 1-10 (2021)
Abstract Rhabdomyosarcomas (RMS) represent a family of aggressive soft tissue sarcomas that present in both children and adults. Pathologic risk stratification for RMS has been based on histologic subtype, with poor outcomes observed in alveolar rhab
Externí odkaz:
https://doaj.org/article/2a65920f1718448eb362b6a801462e28
Autor:
Jocelyn G. Labombarde, Meenu R. Pillai, Marie Wehenkel, Chun-Yang Lin, Rachael Keating, Scott A. Brown, Jeremy Chase Crawford, David C. Brice, Ashley H. Castellaw, Alexandra H. Mandarano, Clifford S. Guy, Juan R. Mejia, Carlessia D. Lewis, Ti-Cheng Chang, Christine M. Oshansky, Sook-San Wong, Richard J. Webby, Mei Yan, Quan–Zhen Li, Tony N. Marion, Paul G. Thomas, Maureen A. McGargill
Publikováno v:
Cell Reports, Vol 38, Iss 10, Pp 110482- (2022)
Summary: Infection and vaccination repeatedly expose individuals to antigens that are conserved between influenza virus subtypes. Nevertheless, antibodies recognizing variable influenza epitopes greatly outnumber antibodies reactive against conserved
Externí odkaz:
https://doaj.org/article/ca04b47d87454606930f357a2413f564
Autor:
Seungjae Lee, Ti-Cheng Chang, Patrick Schreiner, Yiping Fan, Neeraj Agarwal, Charles Owens, Reinhard Dummer, John M. Kirkwood, Raymond L. Barnhill, Dan Theodorescu, Gang Wu, Armita Bahrami
Publikováno v:
Cancers, Vol 14, Iss 16, p 4018 (2022)
Background: TERT promoter methylation, located several hundred base pairs upstream of the transcriptional start site, is cancer specific and correlates with increased TERT mRNA expression and poorer patient outcome. Promoter methylation, however, is
Externí odkaz:
https://doaj.org/article/cce0a52b8eb0422db4daf8a1f405b2b1
Autor:
Ti-Cheng Chang, Robert A. Carter, Yongjin Li, Yuxin Li, Hong Wang, Michael N. Edmonson, Xiang Chen, Paula Arnold, Terrence L. Geiger, Gang Wu, Junmin Peng, Michael Dyer, James R. Downing, Douglas R. Green, Paul G. Thomas, Jinghui Zhang
Publikováno v:
Genome Medicine, Vol 9, Iss 1, Pp 1-12 (2017)
Abstract Background Neoepitopes derived from tumor-specific somatic mutations are promising targets for immunotherapy in childhood cancers. However, the potential for such therapies in targeting these epitopes remains uncertain due to a lack of knowl
Externí odkaz:
https://doaj.org/article/867cf2f09dff4b2da29143808be434ba
Autor:
Sandra Mosquera, Li-Hung Chen, Brenna Aegerter, Eugene Miyao, Anthony Salvucci, Ti-Cheng Chang, Lynn Epstein, Ioannis Stergiopoulos
Publikováno v:
Frontiers in Microbiology, Vol 10 (2019)
Leveillula taurica is a major pathogen of tomato and several other crops that can cause substantial yield losses in favorable conditions for the fungus. Quinone outside inhibitor fungicides (QoIs) are routinely used for the control of the pathogen in
Externí odkaz:
https://doaj.org/article/f82f8ba7634b4fa2a5ea5cd52c69106e
Autor:
Valerie Cortez, Enrique Canal, J Catherine Dupont-Turkowsky, Tatiana Quevedo, Christian Albujar, Ti-Cheng Chang, Gabriela Salmon-Mulanovich, Maria C Guezala-Villavicencio, Mark P Simons, Elisa Margolis, Stacey Schultz-Cherry, Víctor Pacheco, Daniel G Bausch
Publikováno v:
PLoS ONE, Vol 13, Iss 10, p e0205068 (2018)
BACKGROUND:The southern Amazon Basin in the Madre de Dios region of Peru has undergone rapid deforestation and habitat disruption, leading to an unknown zoonotic risk to the growing communities in the area. METHODOLOGY/PRINCIPAL FINDINGS:We surveyed
Externí odkaz:
https://doaj.org/article/c4407d9fac4c4c6f96505f28efebab02
Autor:
Haley Echlin, Matthew W Frank, Amy Iverson, Ti-Cheng Chang, Michael D L Johnson, Charles O Rock, Jason W Rosch
Publikováno v:
PLoS Pathogens, Vol 12, Iss 10, p e1005951 (2016)
The pneumococcus is one of the most prodigious producers of hydrogen peroxide amongst bacterial pathogens. Hydrogen peroxide production by the pneumococcus has been implicated in antibiotic synergism, competition between other bacterial colonizers of
Externí odkaz:
https://doaj.org/article/ffeece64e7d94d6f8aead0dd2553d91f
Publikováno v:
PLoS Genetics, Vol 12, Iss 8, p e1005904 (2016)
The Sigatoka disease complex, caused by the closely-related Dothideomycete fungi Pseudocercospora musae (yellow sigatoka), Pseudocercospora eumusae (eumusae leaf spot), and Pseudocercospora fijiensis (black sigatoka), is currently the most devastatin
Externí odkaz:
https://doaj.org/article/d71dc615b9f547fa8aa9b333ffc17598