Zobrazeno 1 - 10
of 249
pro vyhledávání: '"Thys Van der Molen"'
Autor:
Salman Siddiqui, Thys van der Molen, Huib A M Kerstjens, Dave Singh, Chris Brightling, Maarten van den Berge, Alberto Papi, Klaus F Rabe, Leonardo M Fabbri, Monica Kraft, Martijn C Nawijn, Susan Muiser, Tessa M Kole
Publikováno v:
BMJ Open Respiratory Research, Vol 11, Iss 1 (2024)
Background Asthma is a heterogeneous disease with a prevalence and severity that differs between male and female patients.Question What are differences between male and female patients with asthma with regard to asthma control, lung function, inflamm
Externí odkaz:
https://doaj.org/article/9bc70945e83b454984afcfa5cfa39b16
Autor:
Bruce J. Kirenga, MBChB, MMed, PhD, Jeremiah Chakaya, MBChB, MMed, Getnet Yimer, MD, PhD, George Nyale, MBChB, MMed, Tewodros Haile, MD, Winters Muttamba, MBChB, MPH, Levicatus Mugenyi, PhD, Winceslaus Katagira, MBChB, MMed, William Worodria, MBChB, MMed, PhD, Hellen Aanyu-Tukamuhebwa, MBChB, MMed, Njira Lugogo, MD, Moses Joloba, MBChB, MS, PhD, Tesfaye B. Mersha, PhD, Amsalu Bekele, MD, Fred Makumbi, PhD, Amha Mekasha, PhD, Cynthia L. Green, PhD, Corina de Jong, PhD, Moses Kamya, MBChB, MMed, MPH, PhD, Thys van der Molen, MD, PhD
Publikováno v:
Journal of Allergy and Clinical Immunology: Global, Vol 3, Iss 2, Pp 100209- (2024)
Background: Severe asthma is associated with high morbidity, mortality, and health care utilization, but its burden in Africa is unknown. Objective: We sought to determine the burden (prevalence, mortality, and activity and work impairment) of severe
Externí odkaz:
https://doaj.org/article/ca118668ad9c49588bcccb294bad0081
Autor:
Zaid W. El-Husseini, Dmitry Khalenkow, Andy Lan, Thys van der Molen, Chris Brightling, Alberto Papi, Klaus F. Rabe, Salman Siddiqui, Dave Singh, Monica Kraft, Bianca Beghe, Maarten van den Berge, Djoke van Gosliga, Martijn C. Nawijn, Stefan Rose-John, Gerard H. Koppelman, Reinoud Gosens
Publikováno v:
Respiratory Research, Vol 24, Iss 1, Pp 1-12 (2023)
Abstract Background Asthma is stratified into type 2-high and type 2-low inflammatory phenotypes. Limited success has been achieved in developing drugs that target type 2-low inflammation. Previous studies have linked IL-6 signaling to severe asthma.
Externí odkaz:
https://doaj.org/article/e4d93162eadc447d86daca4b0d26e0df
Autor:
Corina de Jong, Job F. M. van Boven, Michiel R. de Boer, Janwillem W. H. Kocks, Marjolein Y. Berger, Thys van der Molen
Publikováno v:
European Journal of General Practice, Vol 28, Iss 1, Pp 66-74 (2022)
Background Chronic obstructive pulmonary disease (COPD) is a prevalent lung disease. It is assumed that severe patients will receive better treatment in specialised care centres but the prevalence of severe COPD in primary care is high. Integrated pr
Externí odkaz:
https://doaj.org/article/6cac3d7fd6be48348041b0e0cad33e1f
Autor:
Boudewijn J. H. Dierick, Bertine M. J. Flokstra-de Blok, Thys van der Molen, Núria Toledo-Pons, Miguel Román-Rodríguez, Borja G. Cosío, Joan B. Soriano, Janwillem W. H. Kocks, Job F. M. van Boven
Publikováno v:
npj Primary Care Respiratory Medicine, Vol 31, Iss 1, Pp 1-7 (2021)
Abstract Chronic obstructive pulmonary disease (COPD) and asthma impact on work productivity, but their population-based burden and clinical predictors are understudied. In this observational, real-life study, work absence of 14,383 asthma and/or COP
Externí odkaz:
https://doaj.org/article/713c2a2688a741509cbff262ed86fc7a
Autor:
Bruce J. Kirenga, Corina de Jong, Winceslaus Katagira, Samuel Kasozi, Levicatus Mugenyi, Marike Boezen, Thys van der Molen, Moses R. Kamya
Publikováno v:
BMC Public Health, Vol 19, Iss 1, Pp 1-9 (2019)
Abstract Background Recent large-scale population data on the prevalence of asthma and its risk factors are lacking in Uganda. This survey was conducted to address this data gap. Methods A general population based survey was conducted among people
Externí odkaz:
https://doaj.org/article/7fe3e14e44c1490295ff936b9792b184
Autor:
Alexânia de Rê, Fernanda Rodrigues Fonseca, Ana Paula Queiroz, Cardine Martins dos Reis, Marina Mônica Bahl, Janwillem Kocks, Thys van der Molen, Rosemeri Maurici
Publikováno v:
Jornal Brasileiro de Pneumologia, Vol 47, Iss 3 (2021)
ABSTRACT Objective: To test the reliability, validity, and interpretability of the Brazilian version of the Clinical COPD Questionnaire (CCQ) in patients with COPD. Methods: Fifty patients with COPD completed the CCQ by interview on two occasions. At
Externí odkaz:
https://doaj.org/article/082d5bb3cae24c889e9a7eac8f827968
Autor:
Thys van der Molen, Tjip S van der Werf, Hendrik Johannes Prins, Ruud Duijkers, Johannes M A Daniels, Wim Boersma
Publikováno v:
BMJ Open Respiratory Research, Vol 8, Iss 1 (2021)
Background We developed the chronic obstructive pulmonary disease (COPD)-Lower Respiratory Tract Infection-Visual Analogue Score (c-LRTI-VAS) in order to easily quantify symptoms during exacerbations in patients with COPD. This study aimed to validat
Externí odkaz:
https://doaj.org/article/7e94220e30454cd6a410c71aebfa594a
Autor:
Bruce Kirenga, Corina de Jong, Thys van der Molen, Jeremiah Chakaya, Getnet Yimer, George Nyale, Tewodros Haile, Levicatus Mugenyi, Winceslaus Katagira, William Worodria, Njira Lugogo, Moses Joloba, Amsalu Bekele, Fred Makumbi, Cindy Green, Moses Kamya
Publikováno v:
BMJ Open Respiratory Research, Vol 7, Iss 1 (2020)
Rationale The relationship between clinical and biomarker characteristics of asthma and its severity in Africa is not well known.Methods Using the Expert Panel Report 3, we assessed for asthma severity and its relationship with key phenotypic charact
Externí odkaz:
https://doaj.org/article/477a477beea84c2d944c9b37d0a7ef8d
Publikováno v:
Frontiers in Pharmacology, Vol 11 (2020)
Externí odkaz:
https://doaj.org/article/3fbea1edb00b40c8a9716fbb588084cd