Zobrazeno 1 - 4
of 4
pro vyhledávání: '"Thymocytes/metabolism"'
Autor:
Kent Riemondy, Anjana Rao, Brian P. O'Connor, S. Harsha Krovi, Laurent Gapin, Adam R. Lefferts, Jay R. Hesselberth, Leonard L. Dragone, Catherine Halluszczak, Philippa Marrack, Jingjing Zhang, Lisa K. Peterson, Kathryn D. Tuttle, Laura Harmacek, James P. Scott-Browne, Romain Bedel
Publikováno v:
Nature Communications, Vol 9, Iss 1, Pp 1-13 (2018)
Nature Communications
Nature communications, vol. 9, no. 1, pp. 2650
Nature Communications
Nature communications, vol. 9, no. 1, pp. 2650
During development in the thymus, invariant natural killer T (iNKT) cells commit to one of three major functionally different subsets, iNKT1, iNKT2, and iNKT17. Here, we show that T cell antigen receptor (TCR) signal strength governs the development
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f89e4c35d3becfa75c6b45c62a82a633
http://link.springer.com/article/10.1038/s41467-018-05026-6
http://link.springer.com/article/10.1038/s41467-018-05026-6
Autor:
Cosway, E.J., Ohigashi, I., Schauble, K., Parnell, S.M., Jenkinson, W.E., Luther, S., Takahama, Y., Anderson, G.
Publikováno v:
Journal of immunology, vol. 201, no. 2, pp. 516-523
During αβ T cell development in the thymus, migration of newly selected CD4 + and CD8 + thymocytes into medullary areas enables tolerance mechanisms to purge the newly selected αβ TCR repertoire of autoreactive specificities. Thymic dendritic cel
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=od______1900::3f18223b70babaa3106bcebe120dad68
https://serval.unil.ch/notice/serval:BIB_48963E6B5F26
https://serval.unil.ch/notice/serval:BIB_48963E6B5F26
Autor:
Ciarlo, Eleonora, Heinonen, Tytti, Lugrin, Jerome, Acha-Orbea, Hans, Le Roy, Didier, Auwerx, Johan, Roger, Thierry
Publikováno v:
Scientific reports, vol. 7, no. 1, pp. 3853
Scientific Reports
Scientific Reports, Vol 7, Iss 1, Pp 1-10 (2017)
Scientific Reports
Scientific Reports, Vol 7, Iss 1, Pp 1-10 (2017)
Sirtuin 3 (SIRT3) is the main mitochondrial deacetylase. SIRT3 regulates cell metabolism and redox homeostasis, and protects from aging and age-associated pathologies. SIRT3 may drive both oncogenic and tumor-suppressive effects. SIRT3 deficiency has
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid_dedup__::f50ce9b5c1368e584e9197b0db37cefa
https://serval.unil.ch/resource/serval:BIB_CE9836DB152C.P001/REF.pdf
https://serval.unil.ch/resource/serval:BIB_CE9836DB152C.P001/REF.pdf
Publikováno v:
Journal of immunology (Baltimore Md. : 1950)
The Journal of Immunology
Journal of Immunology, Vol. 190, No 2 (2013) pp. 586-96
The Journal of Immunology
Journal of Immunology, Vol. 190, No 2 (2013) pp. 586-96
Lymphoid organs exhibit complex structures tightly related to their function. Surprisingly, although the thymic medulla constitutes a specialized microenvironment dedicated to the induction of T cell tolerance, its three-dimensional topology remains
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::025a0e9ff0cf0d20fee97a76c1217563