Zobrazeno 1 - 10
of 96
pro vyhledávání: '"Thymidine diphosphate"'
Autor:
Hue Thi Nguyen, Yeong So Oh, Kye Woon Cho, Tuoi Thi Le, Ramesh Prasad Pandey, Tae-Su Kim, Jae Kyung Sohng
Publikováno v:
Journal of Microbiology and Biotechnology. 29:268-273
The specificity of a Bacillus licheniformis uridine diphosphate (UDP) glycosyltransferase, YjiC, was increased towards thymidine diphosphate (TDP)-sugar by site-directed mutagenesis. The Arg-282 of YjiC was identified and investigated by substituting
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::8afc8021fb29edff7ee61156f0b89f48
https://doi.org/10.4014/jmb.1811.11009
https://doi.org/10.4014/jmb.1811.11009
Publikováno v:
Acta Crystallographica Section D Structural Biology. 74:341-354
Thymidylate kinase is an important enzyme in DNA synthesis. It catalyzes the conversion of thymidine monophosphate to thymidine diphosphate, with ATP as the preferred phosphoryl donor, in the presence of Mg2+. In this study, the dynamics of the activ
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::26c88d6cbea753001823fc8c0953f572
https://doi.org/10.1107/s2059798318002267
https://doi.org/10.1107/s2059798318002267
Publikováno v:
Journal of Industrial and Engineering Chemistry. 43:13-19
Escherichia coli BL21(DE3)/ΔpgiΔzwfΔgalU mutant was engineered by overexpressing thymidine diphosphate (dTDP)- d -glucose synthase (tgs), dTDP- d -glucose 4,6-dehydratase (dh), and a sugar aminotransferase (wecE) from different sources to produce
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::152572f64ba58e2e2734a2f99691c608
https://doi.org/10.1016/j.jiec.2016.07.054
https://doi.org/10.1016/j.jiec.2016.07.054
Publikováno v:
Tetrahedron Letters. 57:4484-4487
In this study, a competitive assay based on a colorimetric sensing system for thymidine triphosphate (TTP) was developed using 11-mercaptoundecylphosphoric acid functionalized gold nanoparticles (Phos-AuNPs) and a p -xylyl-bis(metal 2+ -cyclen) compl
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::ccaa4f28a6d4d7b70e0e702c18de244f
https://doi.org/10.1016/j.tetlet.2016.08.075
https://doi.org/10.1016/j.tetlet.2016.08.075
Publikováno v:
Acta Crystallographica Section F Structural Biology Communications. 71:1205-1214
The anthracyclines are a class of highly effective natural product chemotherapeutics and are used to treat a range of cancers, including leukemia. The toxicity of the anthracyclines has stimulated efforts to further diversify the scaffold of the natu
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2b9f60ddbe458f81ac8acc2c4460d837
https://doi.org/10.1107/s2053230x15014272
https://doi.org/10.1107/s2053230x15014272
Autor:
Jae Kyung Sohng, Ramesh Prasad Pandey, Luan Luong Chu, Sumangala Darsandhari, Prakash Parajuli
Publikováno v:
Biochemical Engineering Journal. 101:191-199
a b s t r a c t Escherichia coli BL21(DE3) was engineered to divert the flow of carbon flux from glucose-1-phosphate to thymidine diphosphate 4-keto 4,6-dideoxy-D-glucose (dTKDG), an intermediate of various dTDP-sugars. Glucose phosphate isomerase (p
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::c7764969963202e41cd745146e992605
https://doi.org/10.1016/j.bej.2015.05.017
https://doi.org/10.1016/j.bej.2015.05.017
Autor:
Michel Gilbert, Jianjun Li, Evgeny Vinogradov, Alexander S. Riegert, Hazel M. Holden, Anna M Cunningham, Zack Li, Ian C. Schoenhofen, James B. Thoden, Marie-France Goneau
The Gram-negative bacterium Campylobacter jejuni 81116 (Penner serotype HS:6) has a class E lipooligosaccharide (LOS) biosynthesis locus containing 19 genes, which encode for 11 putative glycosyltransferases, 1 lipid A acyltransferase and 7 enzymes t
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::168074fcd17b45c8622ccda4d6956ccb
https://europepmc.org/articles/PMC5441919/
https://europepmc.org/articles/PMC5441919/
Autor:
Hazel M. Holden, James B. Thoden
Publikováno v:
Protein Science. 23:683-692
Unusual di- and trideoxysugars are often found on the O-antigens of Gram-negative bacteria, on the S-layers of Gram-positive bacteria, and on various natural products. One such sugar is 3-acetamido-3,6-dideoxy-d-glucose. A key step in its biosynthesi
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::0bab7509e4585ba2ae549ee1d084bac8
https://doi.org/10.1002/pro.2451
https://doi.org/10.1002/pro.2451
Autor:
Kunal Roy, Probir Kumar Ojha
Publikováno v:
Biosystems. 113:177-195
With the emergence of multi-drug resistance of the currently available antimalarial drugs including the "magic bullet" artemisinin derivatives in the market, there is an urgent need for discovery and development of new potent antimalarial molecules.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9e43cd79f33a293d4634bef69b64a69c
https://doi.org/10.1016/j.biosystems.2013.07.005
https://doi.org/10.1016/j.biosystems.2013.07.005
Publikováno v:
Biochemistry. 52:6114-6126
The outer membranes of Gram-negative bacteria are characterized by a complex lipoglycan referred to as the lipopolysaccharide, or LPS. It can be envisioned in terms of three components: (1) lipid A, which serves to anchor the LPS to the outer membran
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f785f244498ebc18c4d8134254820ae0
https://doi.org/10.1021/bi4009006
https://doi.org/10.1021/bi4009006