Existe-t-il une dose seuil pour les effets génotoxiques ?

Autor: Thybaud, V.

Publikováno v: In Archives des Maladies Professionnelles et de l'Environnement September 2012 73(4):658-666

Derivation of point of departure (PoD) estimates in genetic toxicology studies and their potential applications in risk assessment

Autor: Johnson, G.E., Soeteman‐Hernández, L.G., Gollapudi, B.B., Bodger, O.G., Dearfield, K.L., Heflich, R.H., Hixon, J.G., Lovell, D.P., MacGregor, J.T., Pottenger, L.H., Thompson, C.M., Abraham, L., Thybaud, V., Tanir, J.Y., Zeiger, E., van Benthem, J., White, P.A.

Publikováno v: Environmental and Molecular Mutagenesis

Genetic toxicology data have traditionally been employed for qualitative, rather than quantitative evaluations of hazard. As a continuation of our earlier report that analyzed ethyl methanesulfonate (EMS) and methyl methanesulfonate (MMS) dose–resp

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmid________::4a1ffcf8f8aff4ed74681cb667cd41c5
http://europepmc.org/articles/PMC6710644

SFTG international collaborative study on in vitro micronucleus test. II. Using human lymphocytes

Autor: Clare, M.G., Lorenzon, G., Akhurst, L.C., Marzin, D., van Delft, J.H.M., Montero, R., Botta, A., Bertens, A., Cinelli, S., Thybaud, V., Lorge, E.

Publikováno v: Mutation Research-Genetic Toxicology and Environmental Mutagenesis, 1, 607, 37-60
Mutation Research-Genetic Toxicology and Environmental Mutagenesis, 607(1), 37-60. Elsevier

This study on the in vitro micronucleus assay, comprising 11 laboratories using human lymphocytes, was coordinated by an organizing committee supported by the SFTG (the French branch of the European Environmental Mutagen Society). Nine coded substanc

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=dedup_wf_001::3480d6234c52f29c40d8828a82001aea
http://resolver.tudelft.nl/uuid:82c5f277-8045-4d51-832b-e0e3e2ef2538

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