Zobrazeno 1 - 10
of 19
pro vyhledávání: '"Thutrang T. Nguyen"'
Autor:
Yingleong Chan, Oddgeir L Holmen, Andrew Dauber, Lars Vatten, Aki S Havulinna, Frank Skorpen, Kirsti Kvaløy, Kaisa Silander, Thutrang T Nguyen, Cristen Willer, Michael Boehnke, Markus Perola, Aarno Palotie, Veikko Salomaa, Kristian Hveem, Timothy M Frayling, Joel N Hirschhorn, Michael N Weedon
Publikováno v:
PLoS Genetics, Vol 7, Iss 12, p e1002439 (2011)
Common genetic variants have been shown to explain a fraction of the inherited variation for many common diseases and quantitative traits, including height, a classic polygenic trait. The extent to which common variation determines the phenotype of h
Externí odkaz:
https://doaj.org/article/f9d23eb4bed141c0b87dc27c88ba5d61
Autor:
Charleston W K Chiang, Zofia K Z Gajdos, Joshua M Korn, Finny G Kuruvilla, Johannah L Butler, Rachel Hackett, Candace Guiducci, Thutrang T Nguyen, Rainford Wilks, Terrence Forrester, Christopher A Haiman, Katherine D Henderson, Loic Le Marchand, Brian E Henderson, Mark R Palmert, Colin A McKenzie, Helen N Lyon, Richard S Cooper, Xiaofeng Zhu, Joel N Hirschhorn
Publikováno v:
PLoS Genetics, Vol 6, Iss 3, p e1000866 (2010)
As we move forward from the current generation of genome-wide association (GWA) studies, additional cohorts of different ancestries will be studied to increase power, fine map association signals, and generalize association results to additional popu
Externí odkaz:
https://doaj.org/article/dd8333722d85479091e08623ee749a13
Publikováno v:
Clinical Genetics. 84:213-222
Whole exome sequencing and chromosomal microarrays are two powerful technologies that have transformed the ability of researchers to search for potentially causal variants in human disease. This study combines these tools to search for causal variant
Autor:
Berenice B. Mendonca, Sonir Roberto Rauber Antonini, Brian E. Henderson, Ana Claudia S. Reis, Leticia Ferro Leal, Richard I. Gregory, Thutrang T. Nguyen, Amy B. Emerman, Elena Piskounova, A. P. Silveira-Neto, Vinicius Nahime Brito, Joel N. Hirschhorn, Leticia Ferreira Gontijo Silveira, Ana Claudia Latronico, Cintia Tusset, Mark R. Palmert, Katherine D. Henderson, Daiane Beneduzzi
Publikováno v:
Hormone Research in Paediatrics. 78:144-150
Aim: To investigate LIN28B gene variants in children with idiopathic central precocious puberty (CPP). Patients and Methods: We studied 178 Brazilian children with CPP (171 girls, 16.8% familial cases). A large multiethnic group (1,599 subjects; Mult
Autor:
Helen N. Lyon, Rachel Hackett, Xiaofeng Zhu, Ilze Berzins, Johannah L. Butler, Bamidele O. Tayo, Kristin G. Ardlie, Joel N. Hirschhorn, Charleston W. K. Chiang, Richard S. Cooper, Colin A. McKenzie, Rainford J. Wilks, Amy Luke, Candace Guiducci, Guillaume Lettre, Thutrang T. Nguyen, Cameron D. Palmer, Adebowale Adeyemo, Terrence Forrester, Sun J. Kang, Daniel Shriner, Charles N. Rotimi, Tao Feng
Publikováno v:
Human Molecular Genetics. 19:2725-2738
Genome-wide association (GWA) studies have identified common variants that are associated with a variety of traits and diseases, but most studies have been performed in European-derived populations. Here, we describe the first genome-wide analyses of
Autor:
Alison M. Stuebe, Amy H. Herring, Patricia M. Lenhart, Thutrang T. Nguyen, Kathleen M. Caron, Alison Wise
OBJECTIVE Reduced maternal plasma levels of the peptide vasodilator adrenomedullin have been associated with adverse pregnancy outcomes. We measured the extent to which genetic polymorphisms in the adrenomedullin signaling pathway are associated with
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f7df5f3161457530b28a33fd8c70c231
https://europepmc.org/articles/PMC3982866/
https://europepmc.org/articles/PMC3982866/
Autor:
Alison M. Stuebe, Kari E. North, Amy H. Herring, Thutrang T. Nguyen, Anna Maria Siega-Riz, Alison Wise
Objective To determine whether genetic variants associated with glucose homeostasis are associated with gestational diabetes (GDM). Study Design We genotyped 899 self-identified Caucasian women and 386 self-identified African-American women in the Pr
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::71fd8aef406c866710f63dcfa3e8f789
https://europepmc.org/articles/PMC3884679/
https://europepmc.org/articles/PMC3884679/
Autor:
Acácio P, Silveira-Neto, Leticia Ferro, Leal, Amy B, Emerman, Katherine D, Henderson, Elena, Piskounova, Brian E, Henderson, Richard I, Gregory, Letícia F Gontijo, Silveira, Joel N, Hirschhorn, Thutrang T, Nguyen, Daiane, Beneduzzi, Cintia, Tusset, Ana Claudia S, Reis, Vinicius N, Brito, Berenice B, Mendonca, Mark R, Palmert, Sonir R, Antonini, Ana Claudia, Latronico
Publikováno v:
Hormone research in paediatrics. 78(3)
To investigate LIN28B gene variants in children with idiopathic central precocious puberty (CPP).We studied 178 Brazilian children with CPP (171 girls, 16.8% familial cases). A large multiethnic group (1,599 subjects; Multiethnic Cohort, MEC) was use
Autor:
Kirsti Kvaløy, Aki S. Havulinna, Andrew Dauber, Veikko Salomaa, Yingleong Chan, Kristian Hveem, Thutrang T. Nguyen, Cristen J. Willer, Frank Skorpen, Michael Boehnke, Aarno Palotie, Timothy M. Frayling, Markus Perola, Oddgeir L. Holmen, Lars J. Vatten, Michael N. Weedon, Kaisa Silander, Joel N. Hirschhorn
Publikováno v:
PLoS Genetics
PLoS Genetics, Vol 7, Iss 12, p e1002439 (2011)
PLoS Genetics, Vol 7, Iss 12, p e1002439 (2011)
Common genetic variants have been shown to explain a fraction of the inherited variation for many common diseases and quantitative traits, including height, a classic polygenic trait. The extent to which common variation determines the phenotype of h
Autor:
Thomas O. Carpenter, Etienne Sochett, Steven A. Abrams, Thutrang T. Nguyen, Andrew Dauber, Ronald L. Horst, Joel N. Hirschhorn, David E. C. Cole
Publikováno v:
The Journal of clinical endocrinology and metabolism. 97(2)
Idiopathic infantile hypercalcemia (IIH) is a disorder the genetic etiology and physiological basis of which are not well understood.The objective of the study was to describe the underlying physiology and genetic cause of hypercalcemia in an infant