Zobrazeno 1 - 10
of 216
pro vyhledávání: '"Thushan I. de Silva"'
Autor:
Sheikh Jarju, Rhys D. Wenlock, Madikoi Danso, Dawda Jobe, Ya Jankey Jagne, Alansana Darboe, Michelle Kumado, Yusupha Jallow, Mamlie Touray, Ebrima A. Ceesay, Hoja Gaye, Biran Gaye, Abdoulie Tunkara, Sheriff Kandeh, Marie Gomes, Ellen Lena Sylva, Fatoumata Toure, Hailey Hornsby, Benjamin B. Lindsey, Martin J. Nicklin, Jon R. Sayers, Abdul K. Sesay, Adam Kucharski, David Hodgson, Beate Kampmann, Thushan I. de Silva
Publikováno v:
Nature Communications, Vol 15, Iss 1, Pp 1-10 (2024)
Abstract Little is known about SARS-CoV-2 infection risk in African countries with high levels of infection-driven immunity and low vaccine coverage. We conducted a prospective cohort study of 349 participants from 52 households in The Gambia between
Externí odkaz:
https://doaj.org/article/5435db193440454e888a10f2e338f5cf
Autor:
Oliver Galgut, Fiona Ashford, Alexandra Deeks, Andeep Ghataure, Mimia Islam, Tanvir Sambhi, Yiu Wayn Ker, Christopher J.A. Duncan, Thushan I. de Silva, Susan Hopkins, Victoria Hall, Paul Klenerman, Susanna Dunachie, Alex Richter
Publikováno v:
Vaccine: X, Vol 20, Iss , Pp 100546- (2024)
Introduction: Health care workers (HCWs) have been at increased risk of infection during the SARS-CoV-2 pandemic and as essential workers have been prioritised for vaccination. Due to increased exposure HCW are considered a predictor of what might ha
Externí odkaz:
https://doaj.org/article/710f17acd2cc4dde818cbddcf6dc8c18
Autor:
Bakary Sanyang, Thushan I. de Silva, Bully Camara, Nathalie Beloum, Abdoulie Kanteh, Jarra Manneh, Wouter A.A. de Steenhuijsen Piters, Debby Bogaert, Abdul Karim Sesay, Anna Roca
Publikováno v:
iScience, Vol 27, Iss 9, Pp 110626- (2024)
Summary: Intrapartum azithromycin prophylaxis has shown the potential to reduce maternal infections but showed no effect on neonatal sepsis and mortality. Antibiotic exposure early in life may affect gut microbiota development, leading to undesired c
Externí odkaz:
https://doaj.org/article/103f9ccbbb384ade9fba0b849fddb5f4
Autor:
Hailey Hornsby, Alexander R. Nicols, Stephanie Longet, Chang Liu, Adriana Tomic, Adrienn Angyal, Barbara Kronsteiner, Jessica K. Tyerman, Tom Tipton, Peijun Zhang, Marta Gallis, Piyada Supasa, Muneeswaran Selvaraj, Priyanka Abraham, Isabel Neale, Mohammad Ali, Natalie A. Barratt, Jeremy M. Nell, Lotta Gustafsson, Scarlett Strickland, Irina Grouneva, Timothy Rostron, Shona C. Moore, Luisa M. Hering, Susan L. Dobson, Sagida Bibi, Juthathip Mongkolsapaya, Teresa Lambe, Dan Wootton, Victoria Hall, Susan Hopkins, Tao Dong, Eleanor Barnes, Gavin Screaton, The PITCH Consortium, Alex Richter, Lance Turtle, Sarah L. Rowland-Jones, Miles Carroll, Christopher J. A. Duncan, Paul Klenerman, Susanna J. Dunachie, Rebecca P. Payne, Thushan I. de Silva
Publikováno v:
Nature Communications, Vol 14, Iss 1, Pp 1-16 (2023)
Abstract Pronounced immune escape by the SARS-CoV-2 Omicron variant has resulted in many individuals possessing hybrid immunity, generated through a combination of vaccination and infection. Concerns have been raised that omicron breakthrough infecti
Externí odkaz:
https://doaj.org/article/b703690a29154c058004a652610402dd
Autor:
Saikou Y. Bah, Mariama A. Kujabi, Saffiatou Darboe, Ngange Kebbeh, Bunja F. K. Kebbeh, Abdoulie Kanteh, Ramatouille Bojang, Joy E. Lawn, Beate Kampmann, Abdul K. Sesay, Thushan I. de Silva, Helen Brotherton
Publikováno v:
Communications Medicine, Vol 3, Iss 1, Pp 1-10 (2023)
Abstract Background This detailed genomic study characterised multi-drug resistant-Gram negative bacilli (MDR-GNB) carriage in neonates
Externí odkaz:
https://doaj.org/article/2c741db2beb54dfca225cfa59159c1be
Autor:
Maria Suau Sans, Muhammed Manneh, Isatou Ceesay, Amat Bittaye, Gabrielle de Crombrugghe, Alexander J Keeley, Thushan I de Silva, Jennifer Palmer, Edwin P Armitage, Michael Marks, MRCG Strep A Study Group
Publikováno v:
PLOS Global Public Health, Vol 4, Iss 3, p e0002257 (2024)
Group A Streptococcus (Strep A) bacteria causes a broad spectrum of diseases. The most common manifestations of Strep A infection are sore throat and pus-producing skin infections such as impetigo. Complications of Strep A infection can lead to infla
Externí odkaz:
https://doaj.org/article/bd95419ba3f046889936fdf808b6c17d
Autor:
Edwin P. Armitage, Gabrielle de Crombrugghe, Alex J. Keeley, Fatoumatta E. Camara, Elina Senghore, Amat Bittaye, Musukoi Jammeh, Adam Kucharski, Isatou Ceesay, Haddy Ceesay, Muhammed Manneh, Bunja Samateh, Thushan I. de Silva, Abdul Karim Sesay, Beate Kampmann, Michael Marks
Publikováno v:
Wellcome Open Research, Vol 8 (2023)
Background Streptococcus pyogenes (StrepA) causes a significant burden of disease globally from superficial infections to invasive disease. It is responsible for over 500,000 deaths each year, predominantly in low- and middle-income countries (LMIC).
Externí odkaz:
https://doaj.org/article/0f0cf0039ad24356afaeb9f92a071cee
Autor:
Isabel Neale, Mohammad Ali, Barbara Kronsteiner, Stephanie Longet, Priyanka Abraham, Alexandra S. Deeks, Anthony Brown, Shona C. Moore, Lizzie Stafford, Susan L. Dobson, Megan Plowright, Thomas A. H. Newman, Mary Y. Wu, Edward J. Carr, Rupert Beale, Ashley D. Otter, Susan Hopkins, Victoria Hall, Adriana Tomic, Rebecca P. Payne, Eleanor Barnes, Alex Richter, Christopher J. A. Duncan, Lance Turtle, Thushan I. de Silva, Miles Carroll, Teresa Lambe, Paul Klenerman, Susanna Dunachie
Publikováno v:
mBio, Vol 14, Iss 5 (2023)
ABSTRACT Serological correlates of protection against severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) infection after vaccination (“vaccine breakthrough”) have been described. However, T cell correlates of protection against breakthr
Externí odkaz:
https://doaj.org/article/62986889a29d4d32b1477e895ca6b6cd
Autor:
Daniel M. Williams, Hailey R. Hornsby, Ola M. Shehata, Rebecca Brown, Marta Gallis, Naomi Meardon, Thomas A.H. Newman, Megan Plowright, Domen Zafred, Amber S.M. Shun-Shion, Anthony J. Hodder, Deepa Bliss, Andrew Metcalfe, James R. Edgar, David E. Gordon, Jon R. Sayers, Martin J. Nicklin, Miles Carroll, Paul J. Collini, Stephen Brown, Thushan I. de Silva, Andrew A. Peden
Publikováno v:
iScience, Vol 26, Iss 7, Pp 107056- (2023)
Summary: The prevalence and strength of serological responses mounted toward SARS-CoV-2 proteins other than nucleocapsid (N) and spike (S), which may be of use as additional serological markers, remains underexplored. Using high-content microscopy to
Externí odkaz:
https://doaj.org/article/a5aaa277264a4ecb94d42f577aa50143
Autor:
Matthew D. Parker, Hazel Stewart, Ola M. Shehata, Benjamin B. Lindsey, Dhruv R. Shah, Sharon Hsu, Alexander J. Keeley, David G. Partridge, Shay Leary, Alison Cope, Amy State, Katie Johnson, Nasar Ali, Rasha Raghei, Joe Heffer, Nikki Smith, Peijun Zhang, Marta Gallis, Stavroula F. Louka, Hailey R. Hornsby, Hatoon Alamri, Max Whiteley, Benjamin H. Foulkes, Stella Christou, Paige Wolverson, Manoj Pohare, Samantha E. Hansford, Luke R. Green, Cariad Evans, Mohammad Raza, Dennis Wang, Andrew E. Firth, James R. Edgar, Silvana Gaudieri, Simon Mallal, The COVID-19 Genomics UK (COG-UK) consortium, Mark O. Collins, Andrew A. Peden, Thushan I. de Silva
Publikováno v:
Communications Biology, Vol 5, Iss 1, Pp 1-10 (2022)
Matthew Parker et al. use the ARTIC network tiled amplicon PCR and Oxford Nanopore sequencing of thousands of SARS-CoV-2 samples to detect subgenomic RNA changes in the B.1.1.7 lineage endemic in the UK in late 2020/early 2021. They discovered higher
Externí odkaz:
https://doaj.org/article/a4136fc5fe3f462ca4c6714d58abfce9