Zobrazeno 1 - 10
of 2 950
pro vyhledávání: '"Thursz"'
Autor:
Fardad Soltani, David A. Jenkins, Amit Kaura, Joshua Bradley, Nicholas Black, John P. Farrant, Simon G. Williams, Abdulrahim Mulla, Benjamin Glampson, Jim Davies, Dimitri Papadimitriou, Kerrie Woods, Anoop D. Shah, Mark R. Thursz, Bryan Williams, Folkert W. Asselbergs, Erik K. Mayer, Christopher Herbert, Stuart Grant, Nick Curzen, Iain Squire, Thomas Johnson, Kevin O’Gallagher, Ajay M. Shah, Divaka Perera, Rajesh Kharbanda, Riyaz S. Patel, Keith M. Channon, Richard Lee, Niels Peek, Jamil Mayet, Christopher A. Miller
Publikováno v:
BMC Cardiovascular Disorders, Vol 24, Iss 1, Pp 1-10 (2024)
Abstract Background Heart failure (HF) with preserved or mildly reduced ejection fraction includes a heterogenous group of patients. Reclassification into distinct phenogroups to enable targeted interventions is a priority. This study aimed to identi
Externí odkaz:
https://doaj.org/article/7f7bb0fa6ce44cb6909bc25ffc0b83f6
Autor:
R. Forlano, L. Martinez-Gili, P. Takis, J. Miguens-Blanco, T. Liu, E. Triantafyllou, C. Skinner, R Loomba, M. Thursz, J. R. Marchesi, B.H. Mullish, P. Manousou
Publikováno v:
Gut Microbes, Vol 16, Iss 1 (2024)
ABSTRACTAberration of the “gut-liver axis” contributes to the development and progression of metabolic dysfunction-associated steatotic liver disease (MASLD). Here, we use multi-omics to analyze the gut microbiota composition and metabolic profil
Externí odkaz:
https://doaj.org/article/1939502f166a4f319e35ca45cc3e68b2
Autor:
Tong Liu, Gang Wu, Cathrin L.C. Gudd, Francesca M. Trovato, Thomas Barbera, Yan Liu, Evangelos Triantafyllou, Mark J.W. McPhail, Mark R. Thursz, Wafa Khamri
Publikováno v:
EBioMedicine, Vol 108, Iss , Pp 105336- (2024)
Summary: Background: Immune dysfunction contributes to a high rate of infection in patients with acute decompensation of cirrhosis. CD52 is a glycoprotein prominently expressed in lymphocytes. Immune regulation by CD52 may be involved in adaptive imm
Externí odkaz:
https://doaj.org/article/ba85926b98244f02a120cb26e57cd74a
Autor:
Liu, Tong, Wu, Gang, Gudd, Cathrin L.C., Trovato, Francesca M., Barbera, Thomas, Liu, Yan, Triantafyllou, Evangelos, McPhail, Mark J.W., Thursz, Mark R., Khamri, Wafa
Publikováno v:
In eBioMedicine October 2024 108
Autor:
Amie Ceesay, Sainabou Drammeh, Gibril Ndow, Alpha Omar A. Jallow, Haddy Nyang, Baboucarr Bittaye, Francis S. Mendy, Ousman Secka, Umberto D’Alessandro, Yusuke Shimakawa, Erwan Vo-Quang, Barbara Testoni, Mark Thursz, Maud Lemoine, Isabelle Chemin
Publikováno v:
Microorganisms, Vol 12, Iss 11, p 2273 (2024)
The GeneXpert HBV Viral Load test is a simplified tool to scale up screening and HBV monitoring in resource-limited settings, where HBV is endemic and where molecular techniques to quantify HBV DNA are expensive and scarce. However, the accuracy of f
Externí odkaz:
https://doaj.org/article/3fa41425f9d74f4a8d93c861c48d4df9
Autor:
Charlotte Hateley, Antoni Olona, Laura Halliday, Matthew L. Edin, Jeong-Hun Ko, Roberta Forlano, Ximena Terra, Fred B. Lih, Raúl Beltrán-Debón, Penelopi Manousou, Sanjay Purkayastha, Krishna Moorthy, Mark R. Thursz, Guodong Zhang, Robert D. Goldin, Darryl C. Zeldin, Enrico Petretto, Jacques Behmoaras
Publikováno v:
EBioMedicine, Vol 103, Iss , Pp 105127- (2024)
Summary: Background: Obesity drives maladaptive changes in the white adipose tissue (WAT) which can progressively cause insulin resistance, type 2 diabetes mellitus (T2DM) and metabolic dysfunction-associated liver disease (MASLD). Obesity-mediated l
Externí odkaz:
https://doaj.org/article/f522db65b00f4ac6b5690aad31edc432
Autor:
Nick Powell, Mark R Thursz, Kevin J Woollard, James Larkin, Samra Turajlic, Stephen R Atkinson, Robert D Goldin, Evangelos Triantafyllou, Lucia A Possamai, Charalambos G Antoniades, Cathrin L C Gudd, Eoin Mitchell, Marie-Anne Mawhin
Publikováno v:
Journal for ImmunoTherapy of Cancer, Vol 12, Iss 4 (2024)
Background Checkpoint inhibitor-induced hepatitis (CPI-hepatitis) is an emerging problem with the widening use of CPIs in cancer immunotherapy. Here, we developed a mouse model to characterize the mechanism of CPI-hepatitis and to therapeutically tar
Externí odkaz:
https://doaj.org/article/ef7d49df3e824b6ba015b5adda0e950e
Autor:
Hateley, Charlotte, Olona, Antoni, Halliday, Laura, Edin, Matthew L., Ko, Jeong-Hun, Forlano, Roberta, Terra, Ximena, Lih, Fred B., Beltrán-Debón, Raúl, Manousou, Penelopi, Purkayastha, Sanjay, Moorthy, Krishna, Thursz, Mark R., Zhang, Guodong, Goldin, Robert D., Zeldin, Darryl C., Petretto, Enrico, Behmoaras, Jacques
Publikováno v:
In eBioMedicine May 2024 103
Autor:
Vergis, Nikhil, Patel, Vishal, Bogdanowicz, Karolina, Czyzewska-Khan, Justyna, Keshinro, Rosemary, Fiorentino, Francesca, Day, Emily, Middleton, Paul, Atkinson, Stephen, Tranah, Thomas, Cross, Mary, Babalis, Daphne, Foster, Neil, Lord, Emma, Quaglia, Alberto, Lloyd, Josephine, Goldin, Robert, Rosenberg, William, Parker, Richard, Richardson, Paul, Masson, Steven, Whitehouse, Gavin, Sieberhagan, Cyril, Patch, David, Naoumov, Nikolai, Dhanda, Ashwin, Forrest, Ewan, Thursz, Mark
Publikováno v:
In Clinical Gastroenterology and Hepatology
Autor:
Nguyen, Liem B Luong *, Lemoine, Maud *, Ndow, Gibril, Ward, Zachary J, Hallet, Timothy B, D’Alessandro, Umberto, Thursz, Mark, Nayagam, Shevanthi, Shimakawa, Yusuke *
Publikováno v:
In The Lancet Global Health January 2024 12(1):e66-e78