Zobrazeno 1 - 10
of 20
pro vyhledávání: '"Thulani H. Palpagama"'
Autor:
Andrea Kwakowsky, Thulani H. Palpagama
Publikováno v:
Neural Regeneration Research, Vol 20, Iss 3, Pp 817-818 (2025)
Externí odkaz:
https://doaj.org/article/3d45c682ba8343249d84dbab01e495c3
Autor:
Thulani H. Palpagama, Andrea Kwakowsky
Publikováno v:
Neural Regeneration Research, Vol 20, Iss 1, Pp 207-208 (2025)
Externí odkaz:
https://doaj.org/article/553ee0b4124e43c4ae8b2f26fa09ccc8
Autor:
Mackenzie W. Ferguson, Connor J. Kennedy, Thulani H. Palpagama, Henry J. Waldvogel, Richard L. M. Faull, Andrea Kwakowsky
Publikováno v:
Journal of Central Nervous System Disease, Vol 14 (2022)
Huntington’s disease (HD) is an autosomal neurodegenerative disease that is characterized by an excessive number of CAG trinucleotide repeats within the huntingtin gene ( HTT). HD patients can present with a variety of symptoms including chorea, be
Externí odkaz:
https://doaj.org/article/3ab47fb0ae23401182f6158359918c55
Autor:
Jason H. Y. Yeung, Thulani H. Palpagama, Oliver W. G. Wood, Clinton Turner, Henry J. Waldvogel, Richard L. M. Faull, Andrea Kwakowsky
Publikováno v:
Frontiers in Cellular Neuroscience, Vol 15 (2021)
Alzheimer’s disease (AD) is a neuropathological disorder characterized by the presence and accumulation of amyloid-beta plaques and neurofibrillary tangles. Glutamate dysregulation and the concept of glutamatergic excitotoxicity have been frequentl
Externí odkaz:
https://doaj.org/article/3bb30c1bcc304d64a0d256779681e445
Autor:
Madhavi Pandya, Thulani H. Palpagama, Clinton Turner, Henry J. Waldvogel, Richard L. Faull, Andrea Kwakowsky
Publikováno v:
Biology of Sex Differences, Vol 10, Iss 1, Pp 1-16 (2019)
Abstract Gamma-aminobutyric acid (GABA) is the primary inhibitory neurotransmitter in the nervous system. Previous studies have shown fluctuations in expression levels of GABA signaling components—glutamic acid decarboxylase (GAD), GABA receptor (G
Externí odkaz:
https://doaj.org/article/137fbc50885a45d591a0177aafb03b41
Autor:
Jason H. Y. Yeung, Thulani H. Palpagama, Warren P. Tate, Katie Peppercorn, Henry J. Waldvogel, Richard L. M. Faull, Andrea Kwakowsky
Publikováno v:
Frontiers in Neuroscience, Vol 13 (2020)
Alzheimer’s disease (AD) is the leading type of dementia worldwide. Despite an increasing burden of disease due to a rapidly aging population, there is still a lack of complete understanding of the precise pathological mechanisms which drive its pr
Externí odkaz:
https://doaj.org/article/1203577d0ae94a71a76225c2dd8f9502
Publikováno v:
Frontiers in Molecular Neuroscience, Vol 12 (2019)
Huntington’s disease (HD) is an autosomal dominant neurodegenerative disease. HD patients present with movement disorders, behavioral and psychiatric symptoms and cognitive decline. This review summarizes the contribution of microglia and astrocyte
Externí odkaz:
https://doaj.org/article/c325c6ef58f040bd8ecb34aa1db4d054
Autor:
Thulani H. Palpagama, Henry J Waldvogel, Warren P. Tate, Beatriz Calvo-Flores Guzmán, Jayarjun Ethiraj, Andrea Kwakowsky, Jason H. Y. Yeung, Ying Zhai, Richard L.M. Faull, Katie Peppercorn
Publikováno v:
Journal of Neurochemistry. 155:62-80
Alzheimer's disease (AD) is the leading type of dementia worldwide. With an increasing burden of an aging population coupled with the lack of any foreseeable cure, AD warrants the current intense research effort on the toxic effects of an increased c
Autor:
Richard Faull, Jayarjun Ethiraj, Andrea Kwakowsky, Clinton Turner, Henry J. Waldvogel, Thulani H. Palpagama, Bert van der Werf
Publikováno v:
Scientific Reports
Scientific Reports, Vol 11, Iss 1, Pp 1-14 (2021)
Scientific Reports, Vol 11, Iss 1, Pp 1-14 (2021)
Gamma-aminobutyric acid (GABA) is the primary inhibitory neurotransmitter in the nervous system. The GABA signaling system in the brain is comprised of GABA synthesizing enzymes, transporters, GABAA and GABAB receptors (GABAAR and GABABR). Alteration
Autor:
Andrea Kwakowsky, Oliver W. G. Wood, Richard L.M. Faull, Henry J. Waldvogel, Jason H. Y. Yeung, Clinton Turner, Thulani H. Palpagama
Publikováno v:
Frontiers in Cellular Neuroscience
Frontiers in Cellular Neuroscience, Vol 15 (2021)
Frontiers in Cellular Neuroscience, Vol 15 (2021)
Alzheimer’s disease (AD) is a neuropathological disorder characterized by the presence and accumulation of amyloid-beta plaques and neurofibrillary tangles. Glutamate dysregulation and the concept of glutamatergic excitotoxicity have been frequentl