Zobrazeno 1 - 10
of 94
pro vyhledávání: '"Thuc T Le"'
Publikováno v:
PLoS ONE, Vol 11, Iss 1, p e0146994 (2016)
Uridine is a pyrimidine nucleoside that exerts restorative functions in tissues under stress. Short-term co-administration of uridine with multiple unrelated drugs prevents drug-induced liver lipid accumulation. Uridine has the ability to modulate li
Externí odkaz:
https://doaj.org/article/925e966c72cc4f22a79d6329a451599f
Publikováno v:
PLoS ONE, Vol 10, Iss 7, p e0132105 (2015)
Profiling cellular proteome is critical to understanding signal integration during cell fate determination. In this study, the capability of capillary isoelectric focusing (cIEF) immunoassays to detect post-translational modifications (PTM) of protei
Externí odkaz:
https://doaj.org/article/31b4867d89ea4fe4a35a0449345dac31
Publikováno v:
PLoS ONE, Vol 9, Iss 6, p e99728 (2014)
Purines and pyrimidines are complementary bases of the genetic code. The roles of purines and their derivatives in cellular signal transduction and energy metabolism are well-known. In contrast, the roles of pyrimidines and their derivatives in cellu
Externí odkaz:
https://doaj.org/article/b993d2cd6c944eb495c9a4386f0b9128
Publikováno v:
PLoS ONE, Vol 9, Iss 1, p e87179 (2014)
Uridine, a pyrimidine nucleoside, can modulate liver lipid metabolism although its specific acting targets have not been identified. Using mice with fenofibrate-induced fatty liver as a model system, the effects of uridine on liver lipid metabolism a
Externí odkaz:
https://doaj.org/article/0129ad1792734b31917336946face18e
Publikováno v:
PLoS ONE, Vol 7, Iss 11, p e51092 (2012)
Hepatic microvesicular steatosis is a hallmark of drug-induced hepatotoxicity and early-stage fatty liver disease. Current histopathology techniques are inadequate for the clinical evaluation of hepatic microvesicular steatosis. In this paper, we exp
Externí odkaz:
https://doaj.org/article/6edf65e81f274f7eb06b0b29df533a98
Publikováno v:
PLoS ONE, Vol 7, Iss 6, p e38418 (2012)
Visceral adipose tissue (VAT) inflammation is recognized as a mechanism by which obesity is associated with metabolic diseases. The communication between adipose tissue macrophages (ATMs) and adipocytes is important to understanding the interaction b
Externí odkaz:
https://doaj.org/article/4d098e04e02b409f90268c347069e5e0
Publikováno v:
PLoS ONE, Vol 5, Iss 9 (2010)
The nematode Caenorhabditis elegans has been employed as a model organism to study human obesity due to the conservation of the pathways that regulate energy metabolism. To assay for fat storage in C. elegans, a number of fat-soluble dyes have been e
Externí odkaz:
https://doaj.org/article/231490ea6b74439aa90f562f21ab407e
Autor:
Thuc T Le, Ji-Xin Cheng
Publikováno v:
PLoS ONE, Vol 4, Iss 4, p e5189 (2009)
Phenotypic heterogeneity in a clonal cell population is a well-observed but poorly understood phenomenon. Here, a single-cell approach is employed to investigate non-mutative causes of phenotypic heterogeneity during the differentiation of 3T3-L1 cel
Externí odkaz:
https://doaj.org/article/dc461d7c42f443cba2b15453a1cf6990
Autor:
Yasuyo Urasaki, Thuc T. Le
Publikováno v:
Nutrients; Volume 14; Issue 20; Pages: 4325
Obesity is an established risk factor for metabolic disease. This study explores the functional complementation of anti-adipogenic phytonutrients for obesity prevention and management. Nine phytonutrients were selected based on their ability to affec
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d4dffd0b233cefb2c6e425f3419b1bad
https://pubmed.ncbi.nlm.nih.gov/36297009
https://pubmed.ncbi.nlm.nih.gov/36297009
Publikováno v:
International Journal of Molecular Sciences
Volume 21
Issue 8
International Journal of Molecular Sciences, Vol 21, Iss 2851, p 2851 (2020)
Volume 21
Issue 8
International Journal of Molecular Sciences, Vol 21, Iss 2851, p 2851 (2020)
This study reports a relationship between Akt3 expression and tissue-specific regulation of the pI3K/Akt/mTOR signaling pathway by copaiba essential oil. Akt3, a protein kinase B isoform important for the regulation of neuronal development, exhibited
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6bad3cf9b11a27172549d9ce473fa500