Zobrazeno 1 - 10
of 22
pro vyhledávání: '"Thuan H, Nguyen"'
Autor:
Kunal Reshamwala, Gordon Y. C. Cheung, Roger C. Hsieh, Ryan Liu, Hwang-Soo Joo, Yue Zheng, Justin S. Bae, Thuan H. Nguyen, Amer E. Villaruz, Alfonso S. Gozalo, William R. Elkins, Michael Otto
Publikováno v:
Frontiers in Immunology, Vol 13 (2022)
In contrast to the virulent human skin commensal Staphylococcus aureus, which secretes a plethora of toxins, other staphylococci have much reduced virulence. In these species, commonly the only toxins are those of the phenol-soluble modulin (PSM) fam
Externí odkaz:
https://doaj.org/article/1ab25afc56a24339b5e2705178dfccee
Publikováno v:
Computational and Structural Biotechnology Journal, Vol 18, Iss , Pp 3324-3334 (2020)
Exopolysaccharide is a key part of the extracellular matrix that contributes to important mechanisms of bacterial pathogenicity, most notably biofilm formation and immune evasion. In the human pathogens Staphylococcus aureus and S. epidermidis, as we
Externí odkaz:
https://doaj.org/article/7bb22e705d2c4008bac03099bace4d92
Autor:
Li Qin, Fei Da, Emilie L Fisher, Daniel C S Tan, Thuan H Nguyen, Chih-Lung Fu, Vee Y Tan, Joshua W McCausland, Daniel E Sturdevant, Hwang-Soo Joo, Shu Y Queck, Gordon Y C Cheung, Michael Otto
Publikováno v:
PLoS Pathogens, Vol 13, Iss 2, p e1006153 (2017)
Bacterial sepsis is a major killer in hospitalized patients. Coagulase-negative staphylococci (CNS) with the leading species Staphylococcus epidermidis are the most frequent causes of nosocomial sepsis, with most infectious isolates being methicillin
Externí odkaz:
https://doaj.org/article/0232038b1b1e4dd497951e084a965e80
Publikováno v:
Computational and Structural Biotechnology Journal, Vol 18, Iss, Pp 3324-3334 (2020)
Computational and Structural Biotechnology Journal
Computational and Structural Biotechnology Journal
Graphical abstract
Highlights • PIA is a key extracellular matrix component in staphylococci and other bacteria. • PIA is a cationic, partially deacetylated N-acetylglucosamine polymer. • PIA has a major role in bacterial biofilms and biof
Highlights • PIA is a key extracellular matrix component in staphylococci and other bacteria. • PIA is a cationic, partially deacetylated N-acetylglucosamine polymer. • PIA has a major role in bacterial biofilms and biof
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e77b0ca2e7fa440f6cc6e8afb945e956
http://www.sciencedirect.com/science/article/pii/S2001037020304499
http://www.sciencedirect.com/science/article/pii/S2001037020304499
Autor:
Lei He, Gordon Y. C. Cheung, Thuan H. Nguyen, Trung V. Ho, Anthony J. Yeh, Hwang-Soo Joo, Yue Zheng, Katherine Y. Le, Emilie L. Fisher, Michael Otto, Amer E. Villaruz
Publikováno v:
Journal of Molecular Biology. 431:3015-3027
Phenol-soluble modulins (PSMs) are amphipathic, alpha-helical peptides that are secreted by staphylococci in high amounts in a quorum-sensing-controlled fashion. Studies performed predominantly in Staphylococcus aureus showed that PSMs structure biof
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9fd10539aa4534591cf7332f03089594
https://doi.org/10.1016/j.jmb.2019.03.030
https://doi.org/10.1016/j.jmb.2019.03.030
Autor:
Katherine Y. Le, Thuan H. Nguyen, Rachelle L. Hunt, Gordon Y. C. Cheung, Yue Zheng, Burhan Khan, Michael Otto, Min Li, Lei He, Juraj Kabat, Justin S. Bae
Publikováno v:
Nature Microbiology. 4:1114-1119
Social interactions play an increasingly recognized key role in bacterial physiology1. One of the best studied is quorum sensing (QS), a mechanism by which bacteria sense and respond to the status of cell density2. While QS is generally deemed crucia
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::5debce9d664b82cb8eb7f3b364e98b7f
https://doi.org/10.1038/s41564-019-0413-x
https://doi.org/10.1038/s41564-019-0413-x
Autor:
Thuan H. Nguyen, Gordon Y. C. Cheung, Kevin M. Rigby, Olena Kamenyeva, Juraj Kabat, Daniel E. Sturdevant, Amer E. Villaruz, Ryan Liu, Pipat Piewngam, Adeline R. Porter, Saba Firdous, Janice Chiou, Matthew D. Park, Rachelle L. Hunt, Fawaz M. F. Almufarriji, Vee Y. Tan, Titus K. Asiamah, Joshua W. McCausland, Emilie L. Fisher, Anthony J. Yeh, Justin S. Bae, Scott D. Kobayashi, Ji Ming Wang, Daniel L. Barber, Frank R. DeLeo, Michael Otto
Publikováno v:
Nature microbiology. 7(1)
Swift recruitment of phagocytic leucocytes is critical in preventing infection when bacteria breach through the protective layers of the skin. According to canonical models, this occurs via an indirect process that is initiated by contact of bacteria
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::15ec1ec79a80843d86420c709b55c342
https://pubmed.ncbi.nlm.nih.gov/34952942
https://pubmed.ncbi.nlm.nih.gov/34952942
Autor:
Lei, He, Katherine Y, Le, Burhan A, Khan, Thuan H, Nguyen, Rachelle L, Hunt, Justin S, Bae, Juraj, Kabat, Yue, Zheng, Gordon Y C, Cheung, Min, Li, Michael, Otto
Publikováno v:
Nature microbiology. 4(7)
Social interactions play an increasingly recognized key role in bacterial physiology
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::0adb8e06b396ebb12f565f302f541d1c
https://pubmed.ncbi.nlm.nih.gov/31222172
https://pubmed.ncbi.nlm.nih.gov/31222172
Akademický článek
Tento výsledek nelze pro nepřihlášené uživatele zobrazit.
K zobrazení výsledku je třeba se přihlásit.
K zobrazení výsledku je třeba se přihlásit.
Autor:
Michael Otto, Amer E. Villaruz, Hwang-Soo Joo, Yue Zheng, Kyle A. Glose, Janice Chiou, Seth W. Dickey, Sujiraphong Pharkjaksu, Thuan H. Nguyen, Pattarachai Kiratisin, Gordon Y. C. Cheung, Emilie L. Fisher, Pipat Piewngam, Sunisa Khongthong, Barry Li, Rachelle L. Hunt
Publikováno v:
Nature. 562(7728)
Probiotic nutrition is frequently claimed to improve human health. In particular, live probiotic bacteria obtained with food are thought to reduce intestinal colonization by pathogens, and thus to reduce susceptibility to infection. However, the mech
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::af7f5adb2ffcaecd5fab0e27c9bcd7ca
https://pubmed.ncbi.nlm.nih.gov/30607015
https://pubmed.ncbi.nlm.nih.gov/30607015